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Cullin 4B Produkte

(Cullin 4B (CUL4B))

Kategorien

This gene is a member of the cullin family. The encoded protein forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell. The protein interacts with a ring finger protein, and is required for the proteolysis of several regulators of DNA replication including chromatin licensing and DNA replication factor 1 and cyclin E. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Ausgewählte Cullin 4B Kategorien

Cullin 4B Antikörper

High quality antibodies with extensive validation data.

Cullin 4B Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene Cullin 4B Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, ELISA, IHC (p)
Validierungen
  • (6)
Kat. Nr. ABIN3187726
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, IF
Validierungen
  • (6)
Kat. Nr. ABIN6139255
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Dog, Human, Mouse
Applikation WB, IHC, IHC (p)
Validierungen
  • (6)
Kat. Nr. ABIN1490724
Menge 100 μL
Datenblatt Datenblatt

Empfohlene Cullin 4B ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6215470
Menge 96 tests
Datenblatt Datenblatt

Empfohlene Cullin 4B Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1350769
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr. ABIN3091967
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Mouse
Source Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr. ABIN3130673
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren Cullin 4B Produkten

Aggarwal, Vaites, Kim, Mellert, Gurung, Nakagawa, Herlyn, Hua, Rustgi, McMahon, Diehl: "Nuclear cyclin D1/CDK4 kinase regulates CUL4 expression and triggers neoplastic growth via activation of the PRMT5 methyltransferase." in: Cancer cell, Vol. 18, Issue 4, pp. 329-40, (2010) (PubMed).

Kerzendorfer, Whibley, Carpenter, Outwin, Chiang, Turner, Schwartz, El-Khamisy, Raymond, ODriscoll: "Mutations in Cullin 4B result in a human syndrome associated with increased camptothecin-induced topoisomerase I-dependent DNA breaks." in: Human molecular genetics, Vol. 19, Issue 7, pp. 1324-34, (2010) (PubMed).

Gascoin-Lachambre, Buffat, Rebourcet, Chelbi, Rigourd, Mondon, Mignot, Legras, Simeoni, Vaiman, Barbaux: "Cullins in human intra-uterine growth restriction: expressional and epigenetic alterations." in: Placenta, Vol. 31, Issue 2, pp. 151-7, (2010) (PubMed).

Badura-Stronka, Jamsheer, Materna-Kiryluk, Sowińska, Kiryluk, Budny, Latos-Bieleńska: "A novel nonsense mutation in CUL4B gene in three brothers with X-linked mental retardation syndrome." in: Clinical genetics, Vol. 77, Issue 2, pp. 141-4, (2010) (PubMed).

Abbas, Shibata, Park, Jha, Karnani, Dutta: "CRL4(Cdt2) regulates cell proliferation and histone gene expression by targeting PR-Set7/Set8 for degradation." in: Molecular cell, Vol. 40, Issue 1, pp. 9-21, (2010) (PubMed).

Tarpey, Raymond, OMeara, Edkins, Teague, Butler, Dicks, Stevens, Tofts, Avis, Barthorpe, Buck, Cole, Gray, Halliday, Harrison, Hills, Jenkinson, Jones, Menzies, Mironenko, Perry, Raine, Richardson et al.: "Mutations in CUL4B, which encodes a ubiquitin E3 ligase subunit, cause an X-linked mental retardation syndrome associated with aggressive outbursts, seizures, relative macrocephaly, central obesity, ..." in: American journal of human genetics, Vol. 80, Issue 2, pp. 345-52, (2007) (PubMed).

Zou, Liu, Chen, Zhang, Guo, Zhou, Li, Gao, Guo, Yan, Wei, Shao, Gong: "Mutation in CUL4B, which encodes a member of cullin-RING ubiquitin ligase complex, causes X-linked mental retardation." in: American journal of human genetics, Vol. 80, Issue 3, pp. 561-6, (2007) (PubMed).

Ohtake, Baba, Takada, Okada, Iwasaki, Miki, Takahashi, Kouzmenko, Nohara, Chiba, Fujii-Kuriyama, Kato: "Dioxin receptor is a ligand-dependent E3 ubiquitin ligase." in: Nature, Vol. 446, Issue 7135, pp. 562-6, (2007) (PubMed).

Synonyme und alternative Namen zu Cullin 4B

cullin 4B (CUL4B), cullin 4B (Cul4b), cullin 4B (cul4b), cullin 4B S homeolog (cul4b.S), cullin 4B (Tb927.3.1290), 2700050M05Rik, AA409770, CUL-4B, im:7140950, im:7150765, MGC115611, mKIAA0695, MRXHF2, mrxhf2, MRXS15, MRXSC, mrxsc, RGD1564494, SFM2, sfm2, Tb03.1J15.620

Bezeichner auf Proteinebene für Cullin 4B

  • CUL-4B
  • cullin-4B
  • cullin 4B
  • cullin-4B-like
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