CXCR2 Produkte
(Chemokine (C-X-C Motif) Receptor 2 (CXCR2))
Kategorien
The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. This receptor also binds to chemokine (C-X-C motif) ligand 1 (CXCL1/MGSA), a protein with melanoma growth stimulating activity, and has been shown to be a major component required for serum-dependent melanoma cell growth. This receptor mediates neutrophil migration to sites of inflammation. The angiogenic effects of IL8 in intestinal microvascular endothelial cells are found to be mediated by this receptor. Knockout studies in mice suggested that this receptor controls the positioning of oligodendrocyte precursors in developing spinal cord by arresting their migration. This gene, IL8RA, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36. Alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Nov 2009].
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Ausgewählte CXCR2 Kategorien
CXCR2 Antikörper
High quality antibodies with extensive validation data.
CXCR2 ELISA Kits
Reliable ELISA kits for a wide range of species.
CXCR2 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene CXCR2 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, ELISA
Validierungen
- (5)
- (4)
Kat. Nr.
ABIN732218
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC, FACS, ICC, Neut
Validierungen
- (5)
Kat. Nr.
ABIN7193273
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, ELISA, IHC, IF, ICC
Validierungen
- (5)
Kat. Nr.
ABIN6256283
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene CXCR2 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6965748
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6962628
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6954691
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene CXCR2 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (2)
Kat. Nr.
ABIN7491621
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1350835
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (1)
Kat. Nr.
ABIN6964253
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren CXCR2 Produkten
: "Role of ceramide synthase 2 in G-CSF signaling and G-CSF-R translocation into detergent-resistant membranes." in: Scientific reports, Vol. 9, Issue 1, pp. 747, (2020) (PubMed).: "Mesenchymal Stem Cells Ameliorate Hepatic Ischemia/Reperfusion Injury via Inhibition of Neutrophil Recruitment." in: Journal of immunology research, Vol. 2018, pp. 7283703, (2019) (PubMed).
: "Direct Macromolecular Drug Delivery to Cerebral Ischemia Area using Neutrophil-Mediated Nanoparticles." in: Theranostics, Vol. 7, Issue 13, pp. 3260-3275, (2018) (PubMed).
: "Synergistic IL-6 and IL-8 paracrine signalling pathway infers a strategy to inhibit tumour cell migration." in: Nature communications, Vol. 8, pp. 15584, (2017) (PubMed).
: "Interleukin-8 and Its Receptors in Human Milk from Mothers of Full-Term and Premature Infants." in: Breastfeeding medicine : the official journal of the Academy of Breastfeeding Medicine, Vol. 11, pp. 247-51, (2017) (PubMed).
: "NFATc1 regulates cell proliferation, migration, and invasion of ovarian cancer SKOV3 cells in vitro and in vivo." in: Oncology reports, Vol. 36, Issue 2, pp. 918-28, (2017) (PubMed).
: "Chemotaxis-driven disease-site targeting of therapeutic adult stem cells in dystrophic epidermolysis bullosa." in: Stem cell research & therapy, Vol. 7, Issue 1, pp. 124, (2016) (PubMed).
: "Rac GTPase Activating Protein ARHGAP25 Regulates Leukocyte Transendothelial Migration in Mice." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 197, Issue 7, pp. 2807-15, (2016) (PubMed).
: "B7H3 ameliorates LPS-induced acute lung injury via attenuation of neutrophil migration and infiltration." in: Scientific reports, Vol. 6, pp. 31284, (2016) (PubMed).
: "Evidence for chemokine synergy during neutrophil migration in ARDS." in: Thorax, Vol. 72, Issue 1, pp. 66-73, (2016) (PubMed).
Synonyme und alternative Namen zu CXCR2
C-X-C motif chemokine receptor 2 (Cxcr2), C-X-C motif chemokine receptor 2 (CXCR2), chemokine (C-X-C motif) receptor 2 (Cxcr2), CD128, CD182, CDw128, CDw128b, CMKAR2, Cmkar2, CXC-R2, CXCR-2, Gpcr16, IL-8rb, IL-8Rh, IL8R2, IL8RA, IL8RB, Il8rb, mIL-8RHBezeichner auf Proteinebene für CXCR2
- C-X-C chemokine receptor type 2
- interleukin 8 receptor beta
- interleukin-8 receptor CXCR2
- CXC-R2
- CXCR-2
- CXCR2 gene for IL8 receptor type B
- GRO/MGSA receptor
- IL-8 receptor type 2
- IL-8R B
- chemokine (CXC) receptor 2
- high affinity interleukin-8 receptor B
- interleukin 8 receptor B
- interleukin 8 receptor type 2
- interleukin 8 receptor, beta
- interleukin-8 receptor type B
- chemokine receptor CXCR2
- interleukin 8 receptor, alpha
- IL-8 receptor alpha chain
- chemokine (C-X-C) receptor 2
- IL-8 receptor
- High affinity interleukin-8 receptor B
- interleukin-8 receptor, beta
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