Cyclin D2 Produkte
(Cyclin D2 (CCND2))
Kategorien
The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. Knockout studies of the homologous gene in mouse suggest the essential roles of this gene in ovarian granulosa and germ cell proliferation. High level expression of this gene was observed in ovarian and testicular tumors. [provided by RefSeq, Oct 2008].
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Ausgewählte Cyclin D2 Kategorien
Cyclin D2 Antikörper
High quality antibodies with extensive validation data.
Cyclin D2 ELISA Kits
Reliable ELISA kits for a wide range of species.
Cyclin D2 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene Cyclin D2 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro)
Validierungen
- (1)
- (6)
Kat. Nr.
ABIN738366
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Mouse
Applikation
WB, IHC, IP, ICC
Validierungen
- (6)
Kat. Nr.
ABIN7439681
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC, IF
Validierungen
- (6)
Kat. Nr.
ABIN7153389
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene Cyclin D2 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6966159
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6966158
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6966157
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene Cyclin D2 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1348447
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1348449
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7505225
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren Cyclin D2 Produkten
: "Myeloid leukemia factor-1 is a novel modulator of neonatal rat cardiomyocyte proliferation." in: Biochimica et biophysica acta, Vol. 1864, Issue 4, pp. 634-644, (2017) (PubMed).: "CD274 promotes cell cycle entry of leukemia-initiating cells through JNK/Cyclin D2 signaling." in: Journal of hematology & oncology, Vol. 9, Issue 1, pp. 124, (2017) (PubMed).
: "The Silencing of CCND2 by Promoter Aberrant Methylation in Renal Cell Cancer and Analysis of the Correlation between CCND2 Methylation Status and Clinical Features." in: PLoS ONE, Vol. 11, Issue 9, pp. e0161859, (2016) (PubMed).
: "Reduced expression of microRNA‑206 regulates cell proliferation via cyclinD2 in gliomas." in: Molecular medicine reports, Vol. 11, Issue 5, pp. 3295-300, (2016) (PubMed).
: "miR-198 Represses the Proliferation of HaCaT Cells by Targeting Cyclin D2." in: International journal of molecular sciences, Vol. 16, Issue 8, pp. 17018-28, (2016) (PubMed).
: "Characterization of the human oncogene SCL/TAL1 interrupting locus (Stil) mediated Sonic hedgehog (Shh) signaling transduction in proliferating mammalian dopaminergic neurons." in: Biochemical and biophysical research communications, Vol. 449, Issue 4, pp. 444-8, (2014) (PubMed).
: "HNF4? is a therapeutic target that links AMPK to WNT signalling in early-stage gastric cancer." in: Gut, (2014) (PubMed).
: "Elevated toll-like receptor 3 inhibits pancreatic ?-cell proliferation through G1 phase cell cycle arrest." in: Molecular and cellular endocrinology, Vol. 377, Issue 1-2, pp. 112-22, (2013) (PubMed).
: "RNA deep sequencing as a tool for selection of cell lines for systematic subcellular localization of all human proteins." in: Journal of proteome research, Vol. 12, Issue 1, pp. 299-307, (2013) (PubMed).
: "Mouse development and cell proliferation in the absence of D-cyclins." in: Cell, Vol. 118, Issue 4, pp. 477-91, (2004) (PubMed).
Synonyme und alternative Namen zu Cyclin D2
cyclin D2, b (ccnd2b), cyclin D2 S homeolog (ccnd2.S), cyclin D2 (CCND2), cyclin D2 (ccnd2), G1/S-specific cyclin-D2 (ccnd2), cyclin D2, a (ccnd2a), cyclin D2 (Ccnd2), cyclin D2 L homeolog (ccnd2.L), 2600016F06Rik, AI256817, BF642806, C86853, ccnd2, CCND2, cD2, kiak0002, KIAK0002, LOC100224096, si:ch211-240j22.2, Vin-1, Vin1, zgc:162280Bezeichner auf Proteinebene für Cyclin D2
- cyclin D2
- G1/S-specific cyclin-D2
- ccnd2
- G1/S-specific cyclin D2
- vin-1 proto-oncogene
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