CYP11B2 Produkte
(Cytochrome P450, Family 11, Subfamily B, Polypeptide 2 (CYP11B2))
Kategorien
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane. The enzyme has steroid 18-hydroxylase activity to synthesize aldosterone and 18-oxocortisol as well as steroid 11 beta-hydroxylase activity. Mutations in this gene cause corticosterone methyl oxidase deficiency. [provided by RefSeq, Jul 2008].
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Ausgewählte CYP11B2 Kategorien
CYP11B2 Antikörper
High quality antibodies with extensive validation data.
CYP11B2 ELISA Kits
Reliable ELISA kits for a wide range of species.
CYP11B2 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene CYP11B2 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IF
Validierungen
- (5)
Kat. Nr.
ABIN1679468
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, IHC (p), FACS
Validierungen
- (4)
Kat. Nr.
ABIN655163
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
IHC, IF
Validierungen
- (3)
Kat. Nr.
ABIN7257862
Menge
200 μL
Datenblatt
Datenblatt
Empfohlene CYP11B2 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6955237
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6955238
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Sandwich ELISA
Validierungen
Kat. Nr.
ABIN424543
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene CYP11B2 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Rat
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7392893
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Yeast
Validierungen
Kat. Nr.
ABIN5623843
Menge
500 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN5623846
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren CYP11B2 Produkten
: "The E3 ubiquitin ligase Siah1 regulates adrenal gland organization and aldosterone secretion." in: JCI insight, Vol. 2, Issue 23, (2019) (PubMed).: "[Differences in adrenal steroid hormones production in pubertal rats exposed to low doses of endocrine disruptor DDT during prenatal and postnatal development]." in: Biomeditsinskaia khimiia, Vol. 63, Issue 4, pp. 306-311, (2018) (PubMed).
: "Regulation of CYP11B1 and CYP11B2 steroidogenic genes by hypoxia-inducible miR-10b in H295R cells." in: Marine pollution bulletin, Vol. 85, Issue 2, pp. 344-51, (2014) (PubMed).
: "Isoform-specific monoclonal antibodies against 3β-hydroxysteroid dehydrogenase/isomerase family provide markers for subclassification of human primary aldosteronism." in: The Journal of clinical endocrinology and metabolism, Vol. 99, Issue 2, pp. E257-62, (2014) (PubMed).
: "Structural insights into aldosterone synthase substrate specificity and targeted inhibition." in: Molecular endocrinology (Baltimore, Md.), Vol. 27, Issue 2, pp. 315-24, (2013) (PubMed).
: "The renin-angiotensin-aldosterone system in cerebral small vessel disease." in: Journal of neurology, Vol. 255, Issue 7, pp. 993-1000, (2008) (PubMed).
Synonyme und alternative Namen zu CYP11B2
cytochrome P450 family 11 subfamily B member 2 (CYP11B2), cytochrome P450, family 11, subfamily b, polypeptide 2 (Cyp11b2), aldosterone synthase (Cyp11b2), cytochrome P450, family 11, subfamily B, polypeptide 2 (CYP11B2), cytochrome P450, subfamily XIB (steroid 11-beta-hydroxylase), polypeptide 2 (CYP11B2), ALDOS, Cp45as, CPN2, Cpn2, CYP11B, Cyp11b, Cyp11b-2, Cyp11b3, CYP11BL, CYPXIB2, P-450C18, P450aldo, P450C18, RNCP45ASBezeichner auf Proteinebene für CYP11B2
- aldosterone synthase
- aldosterone-synthesizing enzyme
- cytochrome P-450Aldo
- cytochrome P-450C18
- cytochrome P450 11B2, mitochondrial
- cytochrome P450, subfamily XIB (steroid 11-beta-hydroxylase), polypeptide 2
- mitochondrial cytochrome P450, family 11, subfamily B, polypeptide 2
- steroid 11-beta-monooxygenase
- steroid 11-beta/18-hydroxylase
- steroid 18-hydroxylase, aldosterone synthase, P450C18, P450aldo
- CYPXIB2
- cytochrome P450C11
- steroid 11-beta-hydroxylase
- steroid-11-beta-hydroxylase
- CYPXIB3
- Cytochrome P450 subfamily XIB polypeptide 2 (aldosterone synthase)
- Cytochrome P450, subfamily XIB, polypeptide 2 (aldosterone synthase)
- P450-Aldo-1
- P450-Aldo-2
- cytochrome P450 11B3, mitochondrial
- cytochrome P450, subfamily 11B, polypeptide 2
- cytochrome P450-Aldo-1
- cytochrome P450-Aldo-2
- mitochondrial cytochrome P450 11B2
- cytochrome P450, family 11, subfamily B, polypeptide 2
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