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CYP26A1 Produkte

(Cytochrome P450, Family 26, Subfamily A, Polypeptide 1 (CYP26A1))

Kategorien

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein acts on retinoids, including all-trans-retinoic acid (RA), with both 4-hydroxylation and 18-hydroxylation activities. This enzyme regulates the cellular level of retinoic acid which is involved in regulation of gene expression in both embryonic and adult tissues. Two alternatively spliced transcript variants of this gene, which encode the distinct isoforms, have been reported. [provided by RefSeq, Jul 2008].

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Ausgewählte CYP26A1 Kategorien

CYP26A1 Antikörper

High quality antibodies with extensive validation data.

CYP26A1 ELISA Kits

Reliable ELISA kits for a wide range of species.

CYP26A1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene CYP26A1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC, IF
Validierungen
  • (5)
Kat. Nr. ABIN7266654
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse
Applikation WB, ELISA, IHC, FACS
Validierungen
  • (5)
Kat. Nr. ABIN3030691
Menge 0.4 mL
Datenblatt Datenblatt
Reaktivität Human, Mouse
Applikation WB, IHC (p), FACS
Validierungen
  • (3)
Kat. Nr. ABIN650717
Menge 400 μL
Datenblatt Datenblatt

Empfohlene CYP26A1 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6966246
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6955254
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validierungen
Kat. Nr. ABIN5648174
Menge 96 tests
Datenblatt Datenblatt

Empfohlene CYP26A1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7397558
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Mouse
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7406557
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr. ABIN3078000
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren CYP26A1 Produkten

Brown, Cash, Blihoghe, Johansson, Alnabulsi, Murray: "The expression and prognostic significance of retinoic acid metabolising enzymes in colorectal cancer." in: PLoS ONE, Vol. 9, Issue 3, pp. e90776, (2014) (PubMed).

Lau, Lee, Chang: "Conserved sex-specific timing of meiotic initiation during sex differentiation in the protandrous black porgy Acanthopagrus schlegelii." in: Biology of reproduction, Vol. 88, Issue 6, pp. 150, (2013) (PubMed).

Quere, Baudet, Cassinat, Bertrand, Marti, Manchon, Piquemal, Chomienne, Commes: "Pharmacogenomic analysis of acute promyelocytic leukemia cells highlights CYP26 cytochrome metabolism in differential all-trans retinoic acid sensitivity." in: Blood, Vol. 109, Issue 10, pp. 4450-60, (2007) (PubMed).

Lee, Perera, Coulter, Mohrenweiser, Jetten, Goldstein: "The discovery of new coding alleles of human CYP26A1 that are potentially defective in the metabolism of all-trans retinoic acid and their assessment in a recombinant cDNA expression system." in: Pharmacogenetics and genomics, Vol. 17, Issue 3, pp. 169-80, (2007) (PubMed).

Heise, Mey, Neis, Marquardt, Joussen, Ott, Wiederholt, Kurschat, Megahed, Bickers, Merk, Baron: "Skin retinoid concentrations are modulated by CYP26AI expression restricted to basal keratinocytes in normal human skin and differentiated 3D skin models." in: The Journal of investigative dermatology, Vol. 126, Issue 11, pp. 2473-80, (2006) (PubMed).

Osanai, Petkovich: "Expression of the retinoic acid-metabolizing enzyme CYP26A1 limits programmed cell death." in: Molecular pharmacology, Vol. 67, Issue 5, pp. 1808-17, (2005) (PubMed).

Kumarakulasingham, Rooney, Dundas, Telfer, Melvin, Curran, Murray: "Cytochrome p450 profile of colorectal cancer: identification of markers of prognosis." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 11, Issue 10, pp. 3758-65, (2005) (PubMed).

Sakai, Luo, McCaffery, Hamada, Dräger: "CYP26A1 and CYP26C1 cooperate in degrading retinoic acid within the equatorial retina during later eye development." in: Developmental biology, Vol. 276, Issue 1, pp. 143-57, (2004) (PubMed).

Synonyme und alternative Namen zu CYP26A1

cytochrome P450 family 26 subfamily A member 1 (CYP26A1), cytochrome P450, family 26, subfamily a, polypeptide 1 (Cyp26a1), cytochrome P450 family 26 subfamily A member 1 S homeolog (cyp26a1.S), cytochrome P450 family 26 subfamily A member 1 L homeolog (cyp26a1.L), cytochrome P450, family 26, subfamily A, polypeptide 1 (CYP26A1), cytochrome P450 family 26 subfamily A member 1 (cyp26a1), cytochrome P450, family 26, subfamily A, polypeptide 1 (cyp26a1), cb24, CP26, cp26, CYP26, Cyp26, cyp26, CYP26A, id:ibd5061, P450RA, P450RAI, p450rai, P450RAI1, p450rai1, RACE, RAH, wu:fb81e05, xCYP26, XCYP26A1

Bezeichner auf Proteinebene für CYP26A1

  • P450, retinoic acid-inactivating, 1
  • cytochrome P450 26A1
  • cytochrome P450 retinoic acid-inactivating 1
  • cytochrome P450, subfamily XXVIA, polypeptide 1
  • cytochrome P450RAI
  • hP450RAI
  • retinoic acid 4-hydroxylase
  • retinoic acid-metabolizing cytochrome
  • cytochrome P450, 26, retinoic acid A1
  • retinoic acid hydrolase
  • RACE
  • retinoic acid-converting enzyme
  • retinoic acid-degrading enzyme CYP26
  • xCYP26
  • cytochrome P450, 26, retinoic acid
  • retinoic acid hydroxylase
  • retinoic acid converting enzyme
  • cytochrome P450 retinoic acid hydroxylase
  • cytochrome P450 26
  • etID42255.12
  • gir
  • giraffe
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