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CYP26B1 Produkte

(Cytochrome P450, Family 26, Subfamily B, Polypeptide 1 (CYP26B1))

Kategorien

This gene encodes a member of the cytochrome P450 superfamily. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The encoded protein is localized to the endoplasmic reticulum, and functions as a critical regulator of all-trans retinoic acid levels by the specific inactivation of all-trans retinoic acid to hydroxylated forms. Mutations in this gene are associated with radiohumeral fusions and other skeletal and craniofacial anomalies, and increased levels of the encoded protein are associated with atherosclerotic lesions. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2013].

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Ausgewählte CYP26B1 Kategorien

CYP26B1 Antikörper

High quality antibodies with extensive validation data.

CYP26B1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene CYP26B1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation ELISA, IHC, FACS
Validierungen
  • (5)
Kat. Nr. ABIN185731
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IF
Validierungen
  • (4)
Kat. Nr. ABIN527926
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC (p)
Validierungen
  • (3)
Kat. Nr. ABIN392528
Menge 400 μL
Datenblatt Datenblatt

Empfohlene CYP26B1 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6214669
Menge 96 tests
Datenblatt Datenblatt

Empfohlene CYP26B1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1350948
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1350946
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7415386
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren CYP26B1 Produkten

Foti, Isoherranen, Zelter, Dickmann, Buttrick, Diaz, Douguet: "Identification of Tazarotenic Acid as the First Xenobiotic Substrate of Human Retinoic Acid Hydroxylase CYP26A1 and CYP26B1." in: The Journal of pharmacology and experimental therapeutics, Vol. 357, Issue 2, pp. 281-92, (2016) (PubMed).

Chen, Lee, Hsu, Chen, Wang, Chen, Wang, Huang, Huang: "Expression of a splice variant of CYP26B1 in betel quid-related oral cancer." in: TheScientificWorldJournal, Vol. 2014, pp. 810561, (2014) (PubMed).

Elmabsout, Kumawat, Saenz-Méndez, Krivospitskaya, Sävenstrand, Olofsson, Eriksson, Strid, Valen, Törmä, Sirsjö: "Cloning and functional studies of a splice variant of CYP26B1 expressed in vascular cells." in: PLoS ONE, Vol. 7, Issue 5, pp. e36839, (2012) (PubMed).

Topletz, Thatcher, Zelter, Lutz, Tay, Nelson, Isoherranen: "Comparison of the function and expression of CYP26A1 and CYP26B1, the two retinoic acid hydroxylases." in: Biochemical pharmacology, Vol. 83, Issue 1, pp. 149-63, (2011) (PubMed).

Chen, Lee, Chen, Shieh, Ho, Wang, Lee, Yang, Chen, Chiang, Ko: "CYP26B1 is a novel candidate gene for betel quid-related oral squamous cell carcinoma." in: Oral oncology, Vol. 47, Issue 7, pp. 594-600, (2011) (PubMed).

Tay, Dickmann, Dixit, Isoherranen: "A comparison of the roles of peroxisome proliferator-activated receptor and retinoic acid receptor on CYP26 regulation." in: Molecular pharmacology, Vol. 77, Issue 2, pp. 218-27, (2010) (PubMed).

Pavez Loriè, Li, Vahlquist, Törmä: "The involvement of cytochrome p450 (CYP) 26 in the retinoic acid metabolism of human epidermal keratinocytes." in: Biochimica et biophysica acta, Vol. 1791, Issue 3, pp. 220-8, (2009) (PubMed).

Bowles, Knight, Smith, Wilhelm, Richman, Mamiya, Yashiro, Chawengsaksophak, Wilson, Rossant, Hamada, Koopman: "Retinoid signaling determines germ cell fate in mice." in: Science (New York, N.Y.), Vol. 312, Issue 5773, pp. 596-600, (2006) (PubMed).

Synonyme und alternative Namen zu CYP26B1

cytochrome P450 26B1 (CpipJ_CPIJ002537), cytochrome P450 family 26 subfamily B member 1 L homeolog (cyp26b1.L), cytochrome P450 family 26 subfamily B member 1 (CYP26B1), cytochrome P450 family 26 subfamily B member 1 (cyp26b1), cytochrome P450, family 26, subfamily B, polypeptide 1 (CYP26B1), cytochrome P450, family 26, subfamily b, polypeptide 1 (Cyp26b1), cytochrome P450, family 26, subfamily b, polypeptide 1 (cyp26b1), CP26, cyp26a2, CYP26A2, cyp26b1, fc21d03, p450rai-2, P450RAI-2, P450RAI2, RHFCA, wu:fc21d03, wu:fc26h10, zgc:76999

Bezeichner auf Proteinebene für CYP26B1

  • cytochrome P450 26B1
  • cytochrome P450, family 26, subfamily B, polypeptide 1
  • cytochrome P450 retinoic acid-inactivating 2
  • cytochrome P450 retinoid metabolizing protein
  • cytochrome P450, subfamily XXVIB, polypeptide 1
  • retinoic acid-metabolizing cytochrome
  • cytochrome P450, 26, retinoic acid B1
  • cytochrome P450RAI-2
  • retinoic acid B1
  • retinoic acid hydroxylase
  • dol
  • stocksteif
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