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CYP2C8 Produkte

(Cytochrome P450, Family 2, Subfamily C, Polypeptide 8 (CYP2C8))

Kategorien

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, benzo(a)pyrene, 7-ethyoxycoumarin, and the anti-cancer drug taxol. This gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq, Nov 2010].

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Ausgewählte CYP2C8 Kategorien

CYP2C8 Antikörper

High quality antibodies with extensive validation data.

CYP2C8 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene CYP2C8 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB
Validierungen
  • (2)
Kat. Nr. ABIN514832
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB
Validierungen
  • (2)
Kat. Nr. ABIN947772
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human, Mouse
Applikation ELISA, WB, IHC
Validierungen
  • (2)
Kat. Nr. ABIN6258063
Menge 100 μL
Datenblatt Datenblatt

Empfohlene CYP2C8 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6214689
Menge 96 tests
Datenblatt Datenblatt

Empfohlene CYP2C8 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7122581
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1350971
Menge 25 μg
Datenblatt Datenblatt
Reaktivität Human
Source Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr. ABIN3078039
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren CYP2C8 Produkten

Thomas, Winter, Klumpp, Turpeinen, Klein, Schwab, Zanger: "Peroxisome proliferator-activated receptor alpha, PPARα, directly regulates transcription of cytochrome P450 CYP2C8." in: Frontiers in pharmacology, Vol. 6, pp. 261, (2015) (PubMed).

Leskelä, Jara, Leandro-García, Martínez, García-Donas, Hernando, Hurtado, Vicario, Montero-Conde, Landa, López-Jiménez, Cascón, Milne, Robledo, Rodríguez-Antona: "Polymorphisms in cytochromes P450 2C8 and 3A5 are associated with paclitaxel neurotoxicity." in: The pharmacogenomics journal, Vol. 11, Issue 2, pp. 121-9, (2011) (PubMed).

Pavlov, Ilatovskaya, Levchenko, Mattson, Roman, Staruschenko: "Effects of cytochrome P-450 metabolites of arachidonic acid on the epithelial sodium channel (ENaC)." in: American journal of physiology. Renal physiology, Vol. 301, Issue 3, pp. F672-81, (2011) (PubMed).

Werck-Reichhart, Feyereisen: "Cytochromes P450: a success story." in: Genome biology, Vol. 1, Issue 6, pp. REVIEWS3003, (2001) (PubMed).

Synonyme und alternative Namen zu CYP2C8

cytochrome P450 family 2 subfamily C member 8 (CYP2C8), Cytochrome P450 2C8 (CTN_0597), cytochrome P450, family 2, subfamily C, polypeptide 8 (CYP2C8), cytochrome P450 family 2 subfamily C member 8 S homeolog (cyp2c8.1.S), cytochrome P450 family 2 subfamily C member 8 (cyp2c8.1), CPC8, cpc8, cyp2c8, CYP2C74, CYPIIC8, cypiic8, MP-12/MP-20, mp-12/mp-20

Bezeichner auf Proteinebene für CYP2C8

  • P450 form 1
  • cytochrome P450 2C8
  • cytochrome P450 IIC2
  • cytochrome P450 MP-12
  • cytochrome P450 MP-20
  • cytochrome P450 form 1
  • cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 8
  • flavoprotein-linked monooxygenase
  • microsomal monooxygenase
  • s-mephenytoin 4-hydroxylase
  • xenobiotic monooxygenase
  • Cytochrome P450 2C8
  • cytochrome P450 CYP2C74
  • cytochrome P450, family 2, subfamily C, polypeptide 8
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