CYP3A5 Produkte
(Cytochrome P450, Family 3, Subfamily A, Polypeptide 5 (CYP3A5))
Kategorien
This gene,CYP3A5, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. The enzyme metabolizes drugs such as nifedipine and cyclosporine as well as the steroid hormones testosterone, progesterone and androstenedione. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. This cluster includes a pseudogene, CYP3A5P1, which is very similar to CYP3A5. This similarity has caused some difficulty in determining whether cloned sequences represent the gene or the pseudogene. Multiple alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Jun 2010].
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Ausgewählte CYP3A5 Kategorien
CYP3A5 Antikörper
High quality antibodies with extensive validation data.
CYP3A5 ELISA Kits
Reliable ELISA kits for a wide range of species.
CYP3A5 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene CYP3A5 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, ELISA
Validierungen
- (3)
Kat. Nr.
ABIN7149265
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, ELISA
Validierungen
- (3)
Kat. Nr.
ABIN307112
Menge
200 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC (p), FACS
Validierungen
- (3)
Kat. Nr.
ABIN652394
Menge
400 μL
Datenblatt
Datenblatt
Empfohlene CYP3A5 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6966252
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6955260
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN2946890
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene CYP3A5 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1350994
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3078139
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (1)
Kat. Nr.
ABIN2712776
Menge
20 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren CYP3A5 Produkten
: "Cytochrome P450 3A5 plays a prominent role in the oxidative metabolism of the anti-human immunodeficiency virus drug maraviroc." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 40, Issue 12, pp. 2221-30, (2012) (PubMed).: "Effect of polymorphic CYP3A5 genotype on the single-dose simvastatin pharmacokinetics in healthy subjects." in: Journal of clinical pharmacology, Vol. 47, Issue 1, pp. 87-93, (2006) (PubMed).
: "Contribution of CYP3A5 to hepatic and renal ifosfamide N-dechloroethylation." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 33, Issue 7, pp. 1074-81, (2005) (PubMed).
: "Cytochrome p450 profile of colorectal cancer: identification of markers of prognosis." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 11, Issue 10, pp. 3758-65, (2005) (PubMed).
Synonyme und alternative Namen zu CYP3A5
cytochrome P450 family 3 subfamily A member 5 (CYP3A5), CP35, CYPIIIA5, P450PCN3, PCN3Bezeichner auf Proteinebene für CYP3A5
- cytochrome P450 3A5
- aryl hydrocarbon hydroxylase
- cytochrome P450 HLp2
- cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 5
- cytochrome P450-PCN3
- flavoprotein-linked monooxygenase
- microsomal monooxygenase
- xenobiotic monooxygenase
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