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CYP3A7 Produkte

(Cytochrome P450, Family 3, Subfamily A, Polypeptide 7 (CYP3A7))

Kategorien

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme hydroxylates testosterone and dehydroepiandrosterone 3-sulphate, which is involved in the formation of estriol during pregnancy. The enzyme also metabolizes some drugs such as aflatoxin B1. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Transcript variants have been described, but it is not known whether these transcripts are normally produced. This gene undergoes readthrough transcription with the downstream CYP3AP1 pseudogene, resulting in an isoform with a novel C-terminus, as represented in GeneID:100861540. [provided by RefSeq, Feb 2012].

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Ausgewählte CYP3A7 Kategorien

CYP3A7 Antikörper

High quality antibodies with extensive validation data.

CYP3A7 ELISA Kits

Reliable ELISA kits for a wide range of species.

CYP3A7 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene CYP3A7 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC, IP, ICC
Validierungen
  • (4)
Kat. Nr. ABIN7427744
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation ELISA, IHC, IF
Validierungen
  • (2)
Kat. Nr. ABIN7149266
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC
Validierungen
  • (2)
Kat. Nr. ABIN307113
Menge 200 μg
Datenblatt Datenblatt

Empfohlene CYP3A7 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6955261
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Qualitative Cell ELISA
Validierungen
Kat. Nr. ABIN5648181
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN5653517
Menge 96 tests
Datenblatt Datenblatt

Empfohlene CYP3A7 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1350996
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1350998
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7401020
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren CYP3A7 Produkten

Van Peer, Verbueken, Saad, Casteleyn, Van Ginneken, Van Cruchten: "Ontogeny of CYP3A and P-glycoprotein in the liver and the small intestine of the Göttingen minipig: an immunohistochemical evaluation." in: Basic & clinical pharmacology & toxicology, Vol. 114, Issue 5, pp. 387-94, (2014) (PubMed).

Kumarakulasingham, Rooney, Dundas, Telfer, Melvin, Curran, Murray: "Cytochrome p450 profile of colorectal cancer: identification of markers of prognosis." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 11, Issue 10, pp. 3758-65, (2005) (PubMed).

Leeder, Gaedigk, Marcucci, Gaedigk, Vyhlidal, Schindel, Pearce: "Variability of CYP3A7 expression in human fetal liver." in: The Journal of pharmacology and experimental therapeutics, Vol. 314, Issue 2, pp. 626-35, (2005) (PubMed).

Ogino, Nagata, Yamazoe: "Selective suppressions of human CYP3A forms, CYP3A5 and CYP3A7, by troglitazone in HepG2 cells." in: Drug metabolism and pharmacokinetics, Vol. 17, Issue 1, pp. 42-6, (2004) (PubMed).

Synonyme und alternative Namen zu CYP3A7

cytochrome P450, family 3, subfamily A, polypeptide 7 (CYP3A7), cytochrome P450 family 3 subfamily A member 7 (CYP3A7), CP37, CYPIIIA7, P450-HFLA

Bezeichner auf Proteinebene für CYP3A7

  • cytochrome P450 3A7
  • aryl hydrocarbon hydroxylase
  • cytochrome P450, subfamily IIIA, polypeptide 7
  • cytochrome P450-HFLA
  • flavoprotein-linked monooxygenase
  • microsomal monooxygenase
  • xenobiotic monooxygenase
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