CYP46A1 Produkte
(Cytochrome P450, Family 46, Subfamily A, Polypeptide 1 (CYP46A1))
Kategorien
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed in the brain, where it converts cholesterol to 24S-hydroxycholesterol. While cholesterol cannot pass the blood-brain barrier, 24S-hydroxycholesterol can be secreted in the brain into the circulation to be returned to the liver for catabolism. [provided by RefSeq, Jul 2008].
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Ausgewählte CYP46A1 Kategorien
CYP46A1 Antikörper
High quality antibodies with extensive validation data.
CYP46A1 ELISA Kits
Reliable ELISA kits for a wide range of species.
CYP46A1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene CYP46A1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IP
Validierungen
- (3)
Kat. Nr.
ABIN524256
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
ELISA, IHC
Validierungen
- (2)
Kat. Nr.
ABIN7190421
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Cow, Dog, Goat, Guinea Pig, Horse, Human, Mouse, Rat
Applikation
WB
Validierungen
- (3)
Kat. Nr.
ABIN2773829
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene CYP46A1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN6955263
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene CYP46A1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1351000
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3120164
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3119551
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren CYP46A1 Produkten
: "24(S)-Hydroxycholesterol protects the ex vivo rat retina from injury by elevated hydrostatic pressure." in: Scientific reports, Vol. 6, pp. 33886, (2016) (PubMed).: "Cytochrome P450s and cholesterol homeostasis." in: Pharmacology & therapeutics, Vol. 112, Issue 3, pp. 761-73, (2006) (PubMed).
: "Differential expression of cholesterol hydroxylases in Alzheimer's disease." in: The Journal of biological chemistry, Vol. 279, Issue 33, pp. 34674-81, (2004) (PubMed).
: "Broad substrate specificity of human cytochrome P450 46A1 which initiates cholesterol degradation in the brain." in: Biochemistry, Vol. 42, Issue 48, pp. 14284-92, (2003) (PubMed).
Synonyme und alternative Namen zu CYP46A1
cytochrome P450 family 46 subfamily A member 1 (CYP46A1), cytochrome P450 family 46 subfamily A member 1 L homeolog (cyp46a1.L), cytochrome P450, family 46, subfamily A, polypeptide 1, tandem duplicate 1 (cyp46a1.1), cytochrome P450, family 46 (cyp46a1), cytochrome P450 46A1 (PTRG_08343), cytochrome P450 46A1 (PTRG_09667), cytochrome P450, family 46, subfamily a, polypeptide 1 (Cyp46a1), cholesterol 24-hydroxylase (Sgly_1093), cytochrome P450, family 46, subfamily A, polypeptide 1 (CYP46A1), CP46, CYP46, Cyp46, CYP46A1, MGC147389, zgc:109896Bezeichner auf Proteinebene für CYP46A1
- CH24H
- cholesterol 24-hydroxylase
- cytochrome P450 46A1
- cytochrome P450, subfamily 46 (cholesterol 24-hydroxylase)
- cytochrome P450, family 46, subfamily A, polypeptide 1
- cytochrome P450, family 46
- cholestrol 24-hydroxylase
- cytochrome P450, 46 (cholesterol 24-hydroxylase)
- cytochrome P450, 46a1 (cholesterol 24-hydroxylase)
- cholesterol-24S-hydroxylase
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