DAXX Produkte
(Death-Domain Associated Protein (DAXX))
Kategorien
This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2008].
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Ausgewählte DAXX Kategorien
DAXX Antikörper
High quality antibodies with extensive validation data.
DAXX ELISA Kits
Reliable ELISA kits for a wide range of species.
DAXX Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene DAXX Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IF, PLA
Validierungen
- (5)
Kat. Nr.
ABIN514879
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ICC
Validierungen
- (1)
- (3)
Kat. Nr.
ABIN94302
Menge
0.1 mg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, FACS, ICC
Validierungen
- (4)
Kat. Nr.
ABIN969493
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene DAXX ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6966275
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6966276
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Qualitative Cell ELISA
Validierungen
Kat. Nr.
ABIN1380165
Menge
2 x 96 tests
Datenblatt
Datenblatt
Empfohlene DAXX Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1351120
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1351122
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7424761
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren DAXX Produkten
: "Necrostatin-1 protects hippocampal neurons against ischemia/reperfusion injury via the RIP3/DAXX signaling pathway in rats." in: Neuroscience letters, Vol. 651, pp. 207-215, (2017) (PubMed).: "Epigenetic dysregulation and poorer prognosis in DAXX-deficient pancreatic neuroendocrine tumours." in: Endocrine-related cancer, Vol. 22, Issue 3, pp. L13-8, (2015) (PubMed).
: "Whole-exome sequencing identifies somatic ATRX mutations in pheochromocytomas and paragangliomas." in: Nature communications, Vol. 6, pp. 6140, (2015) (PubMed).
: "ATRX represses alternative lengthening of telomeres." in: Oncotarget, Vol. 6, Issue 18, pp. 16543-58, (2015) (PubMed).
: "TERT promoter mutations are frequent and show association with MED12 mutations in phyllodes tumors of the breast." in: British journal of cancer, Vol. 113, Issue 8, pp. 1244-8, (2015) (PubMed).
: "Altered PTEN, ATRX, CHGA, CHGB, and TP53 expression are associated with aggressive VHL-associated pancreatic neuroendocrine tumors." in: Hormones & cancer, Vol. 4, Issue 3, pp. 165-75, (2013) (PubMed).
: "Sp100 provides intrinsic immunity against human papillomavirus infection." in: mBio, Vol. 4, Issue 6, pp. e00845-13, (2013) (PubMed).
: "Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma. ..." in: Nature, Vol. 482, Issue 7384, pp. 226-31, (2012) (PubMed).
: "Loss of ATRX or DAXX expression and concomitant acquisition of the alternative lengthening of telomeres phenotype are late events in a small subset of MEN-1 syndrome pancreatic neuroendocrine tumors." in: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, Vol. 25, Issue 7, pp. 1033-9, (2012) (PubMed).
: "Altered telomeres in tumors with ATRX and DAXX mutations. ..." in: Science (New York, N.Y.), Vol. 333, Issue 6041, pp. 425, (2011) (PubMed).
Synonyme und alternative Namen zu DAXX
death domain associated protein (DAXX), Fas death domain-associated protein (Daxx), 28S ribosomal protein S29, mitochondrial (LOC100226911), death-domain associated protein (Daxx), death domain associated protein (Daxx), death-associated protein 6 L homeolog (daxx.L), death-domain associated protein (daxx), BING2, DAP6, daxx, EAP1, LOC100226911, si:dz179b20.7, wu:fd15c03Bezeichner auf Proteinebene für DAXX
- CENP-C binding protein
- ETS1-associated protein 1
- Fas-binding protein
- death domain-associated protein 6
- death-associated protein 6
- fas death domain-associated protein
- death-domain associated protein
- death associated protein 3
- Fas death domain-associated protein
- LOW QUALITY PROTEIN: death domain-associated protein 6
- death-associated protein 6 L homeolog
- fas-binding
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