DCC Produkte
(Deleted in Colorectal Carcinoma (DCC))
Kategorien
This gene encodes a netrin 1 receptor. The transmembrane protein is a member of the immunoglobulin superfamily of cell adhesion molecules, and mediates axon guidance of neuronal growth cones towards sources of netrin 1 ligand. The cytoplasmic tail interacts with the tyrosine kinases Src and focal adhesion kinase (FAK, also known as PTK2) to mediate axon attraction. The protein partially localizes to lipid rafts, and induces apoptosis in the absence of ligand. The protein functions as a tumor suppressor, and is frequently mutated or downregulated in colorectal cancer and esophageal carcinoma. [provided by RefSeq, Oct 2009].
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Ausgewählte DCC Kategorien
DCC Antikörper
High quality antibodies with extensive validation data.
DCC ELISA Kits
Reliable ELISA kits for a wide range of species.
DCC Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene DCC Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC (f)
Validierungen
- (6)
- (3)
Kat. Nr.
ABIN967443
Menge
0.1 mg
Datenblatt
Datenblatt
Reaktivität
Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Applikation
WB
Validierungen
- (4)
Kat. Nr.
ABIN2782671
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Mouse
Applikation
WB, IHC (p)
Validierungen
- (2)
Kat. Nr.
ABIN656268
Menge
400 μL
Datenblatt
Datenblatt
Empfohlene DCC ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6966310
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6730147
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene DCC Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7122626
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (1)
Kat. Nr.
ABIN7013754
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (1)
Kat. Nr.
ABIN7013516
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren DCC Produkten
: "Progesterone down-regulates SLIT/ROBO expression in mouse corpus luteum." in: Acta histochemica, Vol. 119, Issue 7, pp. 740-746, (2017) (PubMed).: "Coexpression of high-voltage-activated ion channels Kv3.4 and Cav1.2 in pioneer axons during pathfinding in the developing rat forebrain." in: The Journal of comparative neurology, Vol. 520, Issue 16, pp. 3650-72, (2012) (PubMed).
: "The DCC protein and prognosis in colorectal cancer." in: The New England journal of medicine, Vol. 335, Issue 23, pp. 1727-32, (1996) (PubMed).
: "Expression and alternative splicing of the deleted in colorectal cancer (DCC) gene in normal and malignant tissues." in: Cancer research, Vol. 54, Issue 16, pp. 4493-501, (1994) (PubMed).
: "Identification of a chromosome 18q gene that is altered in colorectal cancers." in: Science (New York, N.Y.), Vol. 247, Issue 4938, pp. 49-56, (1990) (PubMed).
: "Genetic alterations during colorectal-tumor development." in: The New England journal of medicine, Vol. 319, Issue 9, pp. 525-32, (1988) (PubMed).
: "Clonal analysis of human colorectal tumors." in: Science (New York, N.Y.), Vol. 238, Issue 4824, pp. 193-7, (1987) (PubMed).
Synonyme und alternative Namen zu DCC
DCC netrin 1 receptor (DCC), DCC netrin 1 receptor (dcc), deleted in colorectal carcinoma (Dcc), deleted in colorectal carcinoma (dcc), DCC netrin 1 receptor (Dcc), netrin receptor DCC (LOC100712666), C030036D22Rik, CRC18, CRCR1, DCC, Dcc, dcca-A, IGDCC1, Igdcc1, MRMV1, xdcc, XDCCa, zdccBezeichner auf Proteinebene für DCC
- colorectal cancer suppressor
- colorectal tumor suppressor
- deleted in colorectal cancer protein
- immunoglobulin superfamily DCC subclass member 1
- immunoglobulin superfamily, DCC subclass, member 1
- netrin receptor DCC
- tumor suppressor protein DCC
- deleted in colorectal carcinoma
- deleted in colorectal cancer
- deleted in colorectal cancer tumor suppressor
- netrin receptor DCC-like
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