DCLK2 Produkte
(Doublecortin-Like Kinase 2 (DCLK2))
Kategorien
This gene encodes a member of the protein kinase superfamily and the doublecortin family. The protein encoded by this gene contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, a C-terminal serine/threonine protein kinase domain, which shows substantial homology to Ca2+/calmodulin-dependent protein kinase, and a serine/proline-rich domain in between the doublecortin and the protein kinase domains, which mediates multiple protein-protein interactions. The microtubule-polymerizing activity of the encoded protein is independent of its protein kinase activity. Mouse studies show that the DCX gene, another family member, and this gene share function in the establishment of hippocampal organization and that their absence results in a severe epileptic phenotype and lethality, as described in human patients with lissencephaly. Multiple alternatively spliced transcript variants have been identified. [provided by RefSeq, Sep 2010].
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Ausgewählte DCLK2 Kategorien
DCLK2 Antikörper
High quality antibodies with extensive validation data.
DCLK2 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene DCLK2 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, ELISA, IF, ICC
Validierungen
- (3)
Kat. Nr.
ABIN6258107
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB
Validierungen
- (3)
- (1)
Kat. Nr.
ABIN1881253
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IF, ICC
Validierungen
- (2)
Kat. Nr.
ABIN2856229
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene DCLK2 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse
Analytical Method
Qualitative Cell ELISA
Validierungen
Kat. Nr.
ABIN5648188
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene DCLK2 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Insect Cells
Validierungen
Kat. Nr.
ABIN5508892
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7421590
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7423801
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren DCLK2 Produkten
: "The doublecortin gene family and disorders of neuronal structure." in: Central nervous system agents in medicinal chemistry, Vol. 10, Issue 1, pp. 32-46, (2010) (PubMed).: "Mice lacking doublecortin and doublecortin-like kinase 2 display altered hippocampal neuronal maturation and spontaneous seizures." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 16, pp. 6766-71, (2009) (PubMed).
: "Gene trapping: an antibody-dependent approach for verifying integration in your favorite gene." in: Cellular & molecular biology letters, Vol. 13, Issue 4, pp. 614-20, (2008) (PubMed).
: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ..." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, (2002) (PubMed).
Synonyme und alternative Namen zu DCLK2
doublecortin like kinase 2 (DCLK2), doublecortin-like kinase 2 (Dclk2), doublecortin-like kinase 2a (dclk2a), 6330415M09Rik, AU044875, cb572, CL2, CLICK-II, Click-II, CLICK2, CLIK2, DCAMKL2, Dcamkl2, DCDC3, DCDC3B, DCK2, Dck2, dclk, DCLK2, RGD1308384, sb:cb572, si:dkey-180n16.1Bezeichner auf Proteinebene für DCLK2
- CaMK-like CREB regulatory kinase 2
- doublecortin and CaM kinase-like 2
- doublecortin domain-containing protein 3B
- doublecortin-like and CAM kinase-like 2
- serine/threonine-protein kinase DCLK2
- caMK-like CREB regulatory kinase 2
- doublecortin-like kinase 2
- zDCLK
- doublecortin kinase 2
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