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DcR1 Produkte

(Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C))

Kategorien

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL. [provided by RefSeq, Jul 2008].

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Ausgewählte DcR1 Kategorien

DcR1 Antikörper

High quality antibodies with extensive validation data.

DcR1 ELISA Kits

Reliable ELISA kits for a wide range of species.

DcR1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene DcR1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation FACS
Validierungen
  • (3)
Kat. Nr. ABIN301991
Menge 0.1 mg
Datenblatt Datenblatt
Reaktivität Human, Rat
Applikation WB, ELISA, IHC
Validierungen
  • (3)
Kat. Nr. ABIN6265636
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation FACS
Validierungen
  • (2)
Kat. Nr. ABIN6579816
Menge 0.1 mg
Datenblatt Datenblatt

Empfohlene DcR1 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6960280
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN625360
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN5510573
Menge 96 tests
Datenblatt Datenblatt

Empfohlene DcR1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (3)
Kat. Nr. ABIN7275773
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1323146
Menge 25 μg
Datenblatt Datenblatt
Reaktivität Human
Source Human Cells
Validierungen
Kat. Nr. ABIN7319098
Menge 50 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren DcR1 Produkten

Willms, Schittek, Rahn, Sosna, Mert, Adam, Trauzold: "Impact of p53 status on TRAIL-mediated apoptotic and non-apoptotic signaling in cancer cells." in: PLoS ONE, Vol. 14, Issue 4, pp. e0214847, (2019) (PubMed).

Jo, Lee, Lee, Park, Park, Choi, Hong, Kim: "Combination therapy with c-met inhibitor and TRAIL enhances apoptosis in dedifferentiated liposarcoma patient-derived cells." in: BMC cancer, Vol. 19, Issue 1, pp. 496, (2019) (PubMed).

Tawfik, Groth, Gundlach, Peipp, Kabelitz, Becker, Oberg, Trauzold, Wesch: "TRAIL-Receptor 4 Modulates γδ T Cell-Cytotoxicity Toward Cancer Cells." in: Frontiers in immunology, Vol. 10, pp. 2044, (2019) (PubMed).

Shlyakhtina, Pavet, Gronemeyer: "Dual role of DR5 in death and survival signaling leads to TRAIL resistance in cancer cells." in: Cell death & disease, Vol. 8, Issue 8, pp. e3025, (2018) (PubMed).

Singh, Otano, Rombouts, Singh, Peppa, Gill, Böttcher, Kennedy, Oben, Pinzani, Walczak, Fusai, Rosenberg, Maini: "TRAIL regulatory receptors constrain human hepatic stellate cell apoptosis." in: Scientific reports, Vol. 7, Issue 1, pp. 5514, (2017) (PubMed).

Jaworska, Szliszka: "Targeting Apoptotic Activity Against Prostate Cancer Stem Cells." in: International journal of molecular sciences, Vol. 18, Issue 8, (2017) (PubMed).

Hartwig, Montinaro, von Karstedt, Sevko, Surinova, Chakravarthy, Taraborrelli, Draber, Lafont, Arce Vargas, El-Bahrawy, Quezada, Walczak: "The TRAIL-Induced Cancer Secretome Promotes a Tumor-Supportive Immune Microenvironment via CCR2." in: Molecular cell, Vol. 65, Issue 4, pp. 730-742.e5, (2017) (PubMed).

Kim, Woo, Jeong, Ryu, Jang, Jeun: "Potential application of temozolomide in mesenchymal stem cell-based TRAIL gene therapy against malignant glioma." in: Stem cells translational medicine, Vol. 3, Issue 2, pp. 172-82, (2014) (PubMed).

Neumann, Hasenauer, Pollak, Scheurich: "Dominant negative effects of tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) receptor 4 on TRAIL receptor 1 signaling by formation of heteromeric complexes." in: The Journal of biological chemistry, Vol. 289, Issue 23, pp. 16576-87, (2014) (PubMed).

Tang, Lu, Tu, Huang, Fu, Cao, Huang, Cheng, Dai, Zhang: "TRAIL-engineered bone marrow-derived mesenchymal stem cells: TRAIL expression and cytotoxic effects on C6 glioma cells." in: Anticancer research, Vol. 34, Issue 2, pp. 729-34, (2014) (PubMed).

Synonyme und alternative Namen zu DcR1

TNF receptor superfamily member 10c (TNFRSF10C), CD263, DCR1, DCR1-TNFR, LIT, TNFRSF10C, TRAIL-R3, TRAILR3, TRID

Bezeichner auf Proteinebene für DcR1

  • TNF-related apoptosis-inducing ligand receptor 3
  • antagonist decoy receptor for TRAIL/Apo-2L
  • cytotoxic TRAIL receptor-3
  • decoy TRAIL receptor without death domain
  • decoy receptor 1
  • lymphocyte inhibitor of TRAIL
  • tumor necrosis factor receptor superfamily member 10C
  • tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
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