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DEK Produkte

(DEK Oncogene (DEK))
This gene encodes a protein with one SAP domain. This protein binds to cruciform and superhelical DNA and induces positive supercoils into closed circular DNA, and is also involved in splice site selection during mRNA processing. Chromosomal aberrations involving this region, increased expression of this gene, and the presence of antibodies against this protein are all associated with various diseases. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008].

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Ausgewählte DEK Kategorien

DEK Antikörper

High quality antibodies with extensive validation data.

DEK ELISA Kits

Reliable ELISA kits for a wide range of species.

DEK Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene DEK Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IF, FACS, IHC (p)
Validierungen
  • (4)
Kat. Nr. ABIN653133
Menge 400 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, IF
Validierungen
  • (4)
Kat. Nr. ABIN7266724
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IF
Validierungen
  • (3)
  • (4)
Kat. Nr. ABIN968269
Menge 50 μg
Datenblatt Datenblatt

Empfohlene DEK ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN6974951
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Competition ELISA
Validierungen
Kat. Nr. ABIN5591964
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method
Validierungen
Kat. Nr. ABIN1150831
Menge 96 tests
Datenblatt Datenblatt

Empfohlene DEK Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (1)
Kat. Nr. ABIN2719372
Menge 20 μg
Datenblatt Datenblatt
Reaktivität Cat, Human, Monkey, Mouse, Rat
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN2746433
Menge 5 applications
Datenblatt Datenblatt

Neueste Publikationen zu unseren DEK Produkten

Wise-Draper, Sendilnathan, Palackdharry, Pease, Qualtieri, Butler, Sadraei, Morris, Patil, Wilson, Mark, Casper, Takiar, Lane, Privette Vinnedge: "Decreased plasma DEK Oncogene Levels Correlate with p16-Negative Disease and Advanced Tumor Stage in a Case-Control Study of Patients with Head and Neck Squamous Cell Carcinoma." in: Translational oncology, Vol. 11, Issue 1, pp. 168-174, (2018) (PubMed).

Matrka, Cimperman, Haas, Guasch, Ehrman, Waclaw, Komurov, Lane, Wikenheiser-Brokamp, Wells: "Dek overexpression in murine epithelia increases overt esophageal squamous cell carcinoma incidence." in: PLoS genetics, Vol. 14, Issue 3, pp. e1007227, (2018) (PubMed).

Yang, Wu, Geng, Liu, Yang, Chen, Ding, He, Wang, Xie: "Roles of DEK in the endometrium of mice in early pregnancy." in: Gene, Vol. 642, pp. 261-267, (2017) (PubMed).

Wang, Eckert, Zomorrodi, Xin, Pan, Shearer, Weisz, Maranus, Clawson: "Down-regulation of HtrA1 activates the epithelial-mesenchymal transition and ATM DNA damage response pathways." in: PLoS ONE, Vol. 7, Issue 6, pp. e39446, (2012) (PubMed).

Privette Vinnedge, McClaine, Wagh, Wikenheiser-Brokamp, Waltz, Wells: "The human DEK oncogene stimulates ?-catenin signaling, invasion and mammosphere formation in breast cancer." in: Oncogene, Vol. 30, Issue 24, pp. 2741-52, (2011) (PubMed).

Datta, Adelson, Mogilevkin, Mordechai, Sidi, Trama: "Oncoprotein DEK as a tissue and urinary biomarker for bladder cancer." in: BMC cancer, Vol. 11, pp. 234, (2011) (PubMed).

Chen, Gao, Hu, Pang, Cai, Li, Wu, Jiang: "Galactose-poly(ethylene glycol)-polyethylenimine for improved lung gene transfer." in: Biochemical and biophysical research communications, Vol. 375, Issue 3, pp. 378-83, (2008) (PubMed).

Clawson, Bui, Xin, Wang, Pan: "Intracellular localization of the tumor suppressor HtrA1/Prss11 and its association with HPV16 E6 and E7 proteins." in: Journal of cellular biochemistry, Vol. 105, Issue 1, pp. 81-8, (2008) (PubMed).

Fu, Grosveld, Markovitz: "DEK, an autoantigen involved in a chromosomal translocation in acute myelogenous leukemia, binds to the HIV-2 enhancer." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 94, Issue 5, pp. 1811-5, (1997) (PubMed).

Fu, Markovitz: "Purification of the pets factor. A nuclear protein that binds to the inducible TG-rich element of the human immunodeficiency virus type 2 enhancer." in: The Journal of biological chemistry, Vol. 271, Issue 32, pp. 19599-605, (1996) (PubMed).

Synonyme und alternative Namen zu DEK

DEK proto-oncogene (DEK), DEK proto-oncogene (Dek), DEK proto-oncogene L homeolog (dek.L), DEK oncogene (DNA binding) (Dek), DEK oncogene (LOC398543), 1810019E15Rik, D6S231E, D13H6S231E, DEK

Bezeichner auf Proteinebene für DEK

  • DEK oncogene (DNA binding)
  • protein DEK
  • DEK oncogene
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