DERL1 Produkte
(Der1-Like Domain Family, Member 1 (DERL1))
Kategorien
The protein encoded by this gene is a member of the derlin family. Members of this family participate in the ER-associated degradation response and retrotranslocate misfolded or unfolded proteins from the ER lumen to the cytosol for proteasomal degradation. This protein recognizes substrate in the ER and works in a complex to retrotranslocate it across the ER membrane into the cytosol. This protein may select cystic fibrosis transmembrane conductance regulator protein (CFTR) for degradation as well as unfolded proteins in Alzheimer's disease. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Aug 2012].
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Ausgewählte DERL1 Kategorien
DERL1 Antikörper
High quality antibodies with extensive validation data.
DERL1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene DERL1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, IHC (p), FACS
Validierungen
- (4)
Kat. Nr.
ABIN652693
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC
Validierungen
- (2)
Kat. Nr.
ABIN1386486
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, IHC, IHC (p), FACS
Validierungen
- (2)
Kat. Nr.
ABIN1978394
Menge
200 μL
Datenblatt
Datenblatt
Empfohlene DERL1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1351465
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1351467
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren DERL1 Produkten
: "Rab2A is a pivotal switch protein that promotes either secretion or ER-associated degradation of (pro)insulin in insulin-secreting cells." in: Scientific reports, Vol. 4, pp. 6952, (2014) (PubMed).: "HtrA2 regulates beta-amyloid precursor protein (APP) metabolism through endoplasmic reticulum-associated degradation." in: The Journal of biological chemistry, Vol. 282, Issue 38, pp. 28285-95, (2007) (PubMed).
: "Cell biology: a channel for protein waste." in: Nature, Vol. 429, Issue 6994, pp. 817-8, (2004) (PubMed).
Synonyme und alternative Namen zu DERL1
Derlin-1 (Der-1), derlin-1 (EDI_023440), derlin-1.1 (PTRG_01331), hypothetical protein (derl1), Der1-like domain family, member 1 (DERL1), derlin 1 (derl1), derlin 1 L homeolog (derl1.L), derlin 1 (DERL1), Der1-like domain family, member 1 (Derl1), derlin 1 (Derl1), DERLIN-1 (DER1), 1110021N07Rik, AI195141, AW551338, CG10908, DDBDRAFT_0188135, DDBDRAFT_0266772, DDB_0188135, DDB_0266772, DER-1, DER1, Derlin-1, derlin-1, DERLIN-1, Dmel\\CG10908, F17A13.150, F17A13_150, MGC84200, RGD1311835, wu:fb09d07, wu:fb94d05, wu:fj92g12, zgc:55637Bezeichner auf Proteinebene für DERL1
- CG10908-PA
- CG10908-PB
- Der-1-PA
- Der-1-PB
- Dm Derlin-1
- derlin-1
- derlin-1.1
- Der1-like domain family, member 1
- Der1-like protein 1
- degradation in endoplasmic reticulum protein 1
- der1-like protein 1
- DERtrin-1
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