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DGCR8 Produkte

(DiGeorge Syndrome Critical Region Gene 8 (DGCR8))

Kategorien

This gene encodes a subunit of the microprocessor complex which mediates the biogenesis of microRNAs from the primary microRNA transcript. The encoded protein is a double-stranded RNA binding protein that functions as the non-catalytic subunit of the microprocessor complex. This protein is required for binding the double-stranded RNA substrate and facilitates cleavage of the RNA by the ribonuclease III protein, Drosha. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010].

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Ausgewählte DGCR8 Kategorien

DGCR8 Antikörper

High quality antibodies with extensive validation data.

DGCR8 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene DGCR8 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IF
Validierungen
  • (1)
  • (4)
Kat. Nr. ABIN527085
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IP, IF
Validierungen
  • (5)
Kat. Nr. ABIN950085
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC (p)
Validierungen
  • (5)
Kat. Nr. ABIN527086
Menge 100 μg
Datenblatt Datenblatt

Empfohlene DGCR8 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN6203730
Menge 96 tests
Datenblatt Datenblatt

Empfohlene DGCR8 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1351506
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1351505
Menge 25 μg
Datenblatt Datenblatt
Reaktivität Human
Source Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr. ABIN3092171
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren DGCR8 Produkten

Belair, Paikari, Moltzahn, Shenoy, Yau, DallEra, Simko, Benz, Blelloch: "DGCR8 is essential for tumor progression following PTEN loss in the prostate." in: EMBO reports, Vol. 16, Issue 9, pp. 1219-32, (2015) (PubMed).

Márquez, Kohli, Arteta, Chang, Li, Goldblatt, Vidal-Vanaclocha: "Identification of hepatic microvascular adhesion-related genes of human colon cancer cells using random homozygous gene perturbation." in: International journal of cancer. Journal international du cancer, Vol. 133, Issue 9, pp. 2113-22, (2013) (PubMed).

Van Duyne, Guendel, Klase, Narayanan, Coley, Jaworski, Roman, Popratiloff, Mahieux, Kehn-Hall, Kashanchi: "Localization and sub-cellular shuttling of HTLV-1 tax with the miRNA machinery." in: PLoS ONE, Vol. 7, Issue 7, pp. e40662, (2012) (PubMed).

Havens, Reich, Duelli, Hastings: "Biogenesis of mammalian microRNAs by a non-canonical processing pathway." in: Nucleic acids research, Vol. 40, Issue 10, pp. 4626-40, (2012) (PubMed).

Kye, Neveu, Lee, Zhou, Steen, Sahin, Kosik, Silva: "NMDA mediated contextual conditioning changes miRNA expression." in: PLoS ONE, Vol. 6, Issue 9, pp. e24682, (2011) (PubMed).

Luers, Loudig, Berman: "MicroRNAs are expressed and processed by human primary macrophages." in: Cellular immunology, Vol. 263, Issue 1, pp. 1-8, (2010) (PubMed).

Smith, Shah, Cidlowski: "Glucocorticoids modulate microRNA expression and processing during lymphocyte apoptosis." in: The Journal of biological chemistry, Vol. 285, Issue 47, pp. 36698-708, (2010) (PubMed).

Yeom, Lee, Han, Suh, Kim: "Characterization of DGCR8/Pasha, the essential cofactor for Drosha in primary miRNA processing." in: Nucleic acids research, Vol. 34, Issue 16, pp. 4622-9, (2006) (PubMed).

Synonyme und alternative Namen zu DGCR8

DGCR8 microprocessor complex subunit L homeolog (dgcr8.L), DiGeorge syndrome critical region gene 8 (DGCR8), DGCR8 microprocessor complex subunit (dgcr8), DGCR8, microprocessor complex subunit (DGCR8), DGCR8, microprocessor complex subunit (Dgcr8), DGCR8 microprocessor complex subunit (Dgcr8), microRNA 3618 (MIR3618), C22orf12, D16H22S788E, D16H22S1742E, D16Wis2, DGCR8, dgcrk6, DGCRK6, gy1, Gy1, MGC78846, N41, pasha, si:ch211-106a19.4, Vo59c07, wu:fc23f08, wu:fc38f06

Bezeichner auf Proteinebene für DGCR8

  • hypothetical protein LOC432110
  • DiGeorge syndrome critical region gene 8
  • DiGeorge syndrome critical region 8
  • microprocessor complex subunit DGCR8
  • diGeorge syndrome critical region 8 homolog
  • DiGeorge syndrome critical region 8 homolog
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