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Dihydrofolate Reductase Produkte

(Dihydrofolate Reductase (DHFR))
Dihydrofolate reductase converts dihydrofolate into tetrahydrofolate, a methyl group shuttle required for the de novo synthesis of purines, thymidylic acid, and certain amino acids. While the functional dihydrofolate reductase gene has been mapped to chromosome 5, multiple intronless processed pseudogenes or dihydrofolate reductase-like genes have been identified on separate chromosomes. Dihydrofolate reductase deficiency has been linked to megaloblastic anemia. [provided by RefSeq, Jul 2008].

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Ausgewählte Dihydrofolate Reductase Kategorien

Dihydrofolate Reductase Antikörper

High quality antibodies with extensive validation data.

Dihydrofolate Reductase ELISA Kits

Reliable ELISA kits for a wide range of species.

Dihydrofolate Reductase Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene Dihydrofolate Reductase Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA, IF
Validierungen
  • (6)
  • (6)
Kat. Nr. ABIN560600
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Dog, Human, Monkey
Applikation WB, IHC, IF, IHC (p)
Validierungen
  • (7)
Kat. Nr. ABIN1497822
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, IHC (p)
Validierungen
  • (1)
  • (5)
Kat. Nr. ABIN3043286
Menge 100 μg
Datenblatt Datenblatt

Empfohlene Dihydrofolate Reductase ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6966361
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6966363
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6966362
Menge 96 tests
Datenblatt Datenblatt

Empfohlene Dihydrofolate Reductase Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Mouse
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7122665
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN666887
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1351539
Menge 10 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren Dihydrofolate Reductase Produkten

Jabs, Oelze, Mikhed, Stamm, Kröller-Schön, Welschof, Jansen, Hausding, Kopp, Steven, Schulz, Stasch, Münzel, Daiber: "Effect of soluble guanylyl cyclase activator and stimulator therapy on nitroglycerin-induced nitrate tolerance in rats." in: Vascular pharmacology, Vol. 71, pp. 181-91, (2015) (PubMed).

Kossmann, Hu, Steven, Schönfelder, Fraccarollo, Mikhed, Brähler, Knorr, Brandt, Karbach, Becker, Oelze, Bauersachs, Widder, Münzel, Daiber, Wenzel: "Inflammatory monocytes determine endothelial nitric-oxide synthase uncoupling and nitro-oxidative stress induced by angiotensin II." in: The Journal of biological chemistry, Vol. 289, Issue 40, pp. 27540-50, (2014) (PubMed).

Oelze, Kröller-Schön, Welschof, Jansen, Hausding, Mikhed, Stamm, Mader, Zinßius, Agdauletova, Gottschlich, Steven, Schulz, Bottari, Mayoux, Münzel, Daiber et al.: "The sodium-glucose co-transporter 2 inhibitor empagliflozin improves diabetes-induced vascular dysfunction in the streptozotocin diabetes rat model by interfering with oxidative stress and ..." in: PLoS ONE, Vol. 9, Issue 11, pp. e112394, (2014) (PubMed).

Tian, Zhang, Ge, Xiao, Lu, Fu, Liu, Sun: "MicroRNA-205 suppresses proliferation and promotes apoptosis in laryngeal squamous cell carcinoma." in: Medical oncology (Northwood, London, England), Vol. 31, Issue 1, pp. 785, (2013) (PubMed).

Vodenicharov, Laterreur, Wellinger: "Telomere capping in non-dividing yeast cells requires Yku and Rap1." in: The EMBO journal, Vol. 29, Issue 17, pp. 3007-19, (2010) (PubMed).

Yoon, Choi, Kim, Shin, Zhang, Kang: "Influence of reduced folate carrier and dihydrofolate reductase genes on methotrexate-induced cytotoxicity." in: Cancer research and treatment : official journal of Korean Cancer Association, Vol. 42, Issue 3, pp. 163-71, (2010) (PubMed).

Ionova, Vásquez-Vivar, Whitsett, Herrnreiter, Medhora, Cooley, Pieper: "Deficient BH4 production via de novo and salvage pathways regulates NO responses to cytokines in adult cardiac myocytes." in: American journal of physiology. Heart and circulatory physiology, Vol. 295, Issue 5, pp. H2178-87, (2008) (PubMed).

Eymin, Gazzeri, Brambilla, Brambilla: "Distinct pattern of E2F1 expression in human lung tumours: E2F1 is upregulated in small cell lung carcinoma." in: Oncogene, Vol. 20, Issue 14, pp. 1678-87, (2001) (PubMed).

de Wind, Dekker, Claij, Jansen, van Klink, Radman, Riggins, van der Valk, vant Wout, te Riele: "HNPCC-like cancer predisposition in mice through simultaneous loss of Msh3 and Msh6 mismatch-repair protein functions." in: Nature genetics, Vol. 23, Issue 3, pp. 359-62, (1999) (PubMed).

Tang, Pao, Zhang: "Repair of benzo(a)pyrene diol epoxide- and UV-induced DNA damage in dihydrofolate reductase and adenine phosphoribosyltransferase genes of CHO cells." in: The Journal of biological chemistry, Vol. 269, Issue 17, pp. 12749-54, (1994) (PubMed).

Synonyme und alternative Namen zu Dihydrofolate Reductase

confers resistance to sulfonamides (dhfr), dihydrofolate reductase (DHFR), dihydrofolate reductase (dhfR), dihydrofolate reductase (dhfr), dihydrofolate reductase (folA), dihydrofolate reductase (dfrA), dihydrofolate reductase (LOC707382), dihydrofolate reductase DhfR (dhfR), dihydrofolate reductase (CNJ01940), dihydrofolate reductase (DDB_G0286755), Dihydrofolate reductase (Dhfr), Dihydrofolate reductase (Mesil_0096), Dihydrofolate reductase (Arch_0408), dihydrofolate reductase (Fbal_3367), dihydrofolate reductase (Ilyop_0482), dihydrofolate reductase (Lbys_2007), dihydrofolate reductase (Riean_0733), Dihydrofolate reductase (Mrub_1855), Dihydrofolate reductase (Poras_0766), dihydrofolate reductase (Halhy_3552), dihydrofolate reductase (Mesop_3614), dihydrofolate reductase (LOC609048), dihydrofolate reductase (Dhfr), 8430436I03Rik, AA607882, AI662710, AW555094, cb595, CG14887, DDBDRAFT_0187132, DDBDRAFT_0230113, DDB_0187132, DDB_0230113, DHFR, dhfr, Dhfr1, DHFRP1, Dmel\\CG14887, DYR, ECK0049, F10_orf160, JW0047, tmrA, zgc:86637

Bezeichner auf Proteinebene für Dihydrofolate Reductase

  • dihydrofolate reductase
  • dihydrofolate reductase DhfR
  • CG14887-PA
  • CG14887-PB
  • Dhfr-PA
  • Dhfr-PB
  • Dihydrofolate reductase
  • Dihydrofolate reductase 1 (active)
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