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DIO2 Produkte

(Deiodinase, Iodothyronine, Type II (DIO2))
The protein encoded by this gene belongs to the iodothyronine deiodinase family. It activates thyroid hormone by converting the prohormone thyroxine (T4) by outer ring deiodination (ORD) to bioactive 3,3',5-triiodothyronine (T3). It is highly expressed in the thyroid, and may contribute significantly to the relative increase in thyroidal T3 production in patients with Graves disease and thyroid adenomas. This protein contains selenocysteine (Sec) residues encoded by the UGA codon, which normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].

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Ausgewählte DIO2 Kategorien

DIO2 Antikörper

High quality antibodies with extensive validation data.

DIO2 ELISA Kits

Reliable ELISA kits for a wide range of species.

DIO2 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene DIO2 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse
Applikation WB, IHC (p), FACS
Validierungen
  • (5)
Kat. Nr. ABIN652664
Menge 400 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse
Applikation ELISA, IHC, FACS, IF
Validierungen
  • (1)
  • (3)
Kat. Nr. ABIN190862
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation ELISA, IHC, IF
Validierungen
  • (2)
Kat. Nr. ABIN7173972
Menge 100 μg
Datenblatt Datenblatt

Empfohlene DIO2 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Competition ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6966307
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6955327
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6955328
Menge 96 tests
Datenblatt Datenblatt

Empfohlene DIO2 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1351608
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7413544
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Mouse
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7413547
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren DIO2 Produkten

Zuo, Liu, Gao, Yin, Wang, Hou, Fu, Liu, Wang, Xu, Pi: "Prolonged inorganic arsenic exposure via drinking water impairs brown adipose tissue function in mice." in: The Science of the total environment, Vol. 668, pp. 310-317, (2019) (PubMed).

Ma, Brouwer, Wesseling, Raj, van der Want, Boddeke, Balasubramaniyan, Copray: "Multipotent stem cell factor UGS148 is a marker for tanycytes in the adult hypothalamus." in: Molecular and cellular neurosciences, Vol. 65, pp. 21-30, (2015) (PubMed).

Kishida, Ejima, Yamamoto, Tanaka, Yamamoto, Mazda: "Reprogrammed Functional Brown Adipocytes Ameliorate Insulin Resistance and Dyslipidemia in Diet-Induced Obesity and Type 2 Diabetes." in: Stem cell reports, Vol. 5, Issue 4, pp. 569-81, (2015) (PubMed).

Vose, Vinukonda, Jo, Miry, Diamond, Korumilli, Arshad, Zia, Hu, Kayton, La Gamma, Bansal, Bianco, Ballabh: "Treatment with thyroxine restores myelination and clinical recovery after intraventricular hemorrhage." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 33, Issue 44, pp. 17232-46, (2013) (PubMed).

Langford, Baron, Joy, Del Valle, Shack: "Contributions of HIV infection in the hypothalamus and substance abuse/use to HPT dysregulation." in: Psychoneuroendocrinology, Vol. 36, Issue 5, pp. 710-9, (2011) (PubMed).

Gumieniak, Perlstein, Williams, Hopkins, Brown, Raby, Williams: "Ala92 type 2 deiodinase allele increases risk for the development of hypertension." in: Hypertension, Vol. 49, Issue 3, pp. 461-6, (2007) (PubMed).

Synonyme und alternative Namen zu DIO2

iodothyronine deiodinase 2 (DIO2), deiodinase, iodothyronine, type II (Dio2), iodothyronine deiodinase 2 (dio2), deiodinase, iodothyronine, type II (dio2), deiodinase, iodothyronine, type 2 L homeolog (dio2.L), deiodinase, iodothyronine, type 2 (dio2), iodothyronine deiodinase 2 (Dio2), type II iodothyronine deiodinase (LOC100861220), 5DII, 5dii, AI324267, cb684, D2, Deio2, DIO2, dio2-A, DIOII, SelY, sely, TXDI2, txdi2

Bezeichner auf Proteinebene für DIO2

  • thyroxine deiodinase, type II
  • type 2 DI
  • type 2 iodothyronine deiodinase
  • type II iodothyronine deiodinase
  • type-II 5'-deiodinase
  • type-II 5'deiodinase
  • iodothyronine type II deiodinase
  • type-II 5' deiodinase
  • deiodinase, iodothyronine, type 2
  • D2
  • 5DII
  • DIOII
  • deiodinase, iodothyronine, type II
  • deiodinase 2
  • type 2 deiodinase
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