DKK2 Produkte
(Dickkopf 2 Homolog (DKK2))
Kategorien
This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. It can act as either an agonist or antagonist of Wnt/beta-catenin signaling, depending on the cellular context and the presence of the co-factor kremen 2. Activity of this protein is also modulated by binding to the Wnt co-receptor LDL-receptor related protein 6 (LRP6). [provided by RefSeq, Jul 2008].
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Ausgewählte DKK2 Kategorien
DKK2 Antikörper
High quality antibodies with extensive validation data.
DKK2 ELISA Kits
Reliable ELISA kits for a wide range of species.
DKK2 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene DKK2 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC
Validierungen
- (3)
Kat. Nr.
ABIN7149882
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Bat, Dog, Guinea Pig, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat
Applikation
WB, IHC, IHC (p)
Validierungen
- (3)
Kat. Nr.
ABIN6749760
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IP, ICC
Validierungen
- (2)
Kat. Nr.
ABIN7433045
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene DKK2 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (2)
- (1)
Kat. Nr.
ABIN6955381
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6966354
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6966352
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene DKK2 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7122658
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (1)
Kat. Nr.
ABIN6964354
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7539309
Menge
20 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren DKK2 Produkten
: "Differential effects on lung and bone metastasis of breast cancer by Wnt signalling inhibitor DKK1." in: Nature cell biology, Vol. 19, Issue 10, pp. 1274-1285, (2017) (PubMed).: "Rheumatoid arthritis bone fragility is associated with upregulation of IL17 and DKK1 gene expression." in: Clinical reviews in allergy & immunology, Vol. 47, Issue 1, pp. 38-45, (2014) (PubMed).
: "DKK2 mediates osteolysis, invasiveness, and metastatic spread in Ewing sarcoma." in: Cancer research, Vol. 73, Issue 2, pp. 967-77, (2013) (PubMed).
: "Genistein downregulates onco-miR-1260b and inhibits Wnt-signalling in renal cancer cells." in: British journal of cancer, Vol. 108, Issue 10, pp. 2070-8, (2013) (PubMed).
: "Epigenetic silencing of DKK2 and Wnt signal pathway components in human ovarian carcinoma." in: Carcinogenesis, Vol. 33, Issue 12, pp. 2334-43, (2012) (PubMed).
: "Expression pattern of REIC/Dkk-3 in various cell types and the implications of the soluble form in prostatic acinar development." in: International journal of oncology, Vol. 37, Issue 6, pp. 1495-501, (2011) (PubMed).
: "Wnt antagonist gene DKK2 is epigenetically silenced and inhibits renal cancer progression through apoptotic and cell cycle pathways." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 15, Issue 18, pp. 5678-87, (2009) (PubMed).
: "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. ..." in: Genome research, Vol. 13, Issue 10, pp. 2265-70, (2003) (PubMed).
: "Regulation of Wnt/LRP signaling by distinct domains of Dickkopf proteins." in: Molecular and cellular biology, Vol. 22, Issue 17, pp. 6100-10, (2002) (PubMed).
: "Functional and structural diversity of the human Dickkopf gene family." in: Gene, Vol. 238, Issue 2, pp. 301-13, (1999) (PubMed).
Synonyme und alternative Namen zu DKK2
dickkopf WNT signaling pathway inhibitor 2 (DKK2), dickkopf WNT signaling pathway inhibitor 2 (Dkk2), dickkopf WNT signaling pathway inhibitor 2 (dkk2), DKK-2, Dkk4, zgc:171574Bezeichner auf Proteinebene für DKK2
- dickkopf 2 homolog
- dickkopf homolog 2
- dickkopf related protein-2
- dickkopf-2
- dickkopf-related protein 2
- hDkk-2
- dickkopf 2
- dickkopf homolog 1
- dkk-2
- mDkk-2
- dickkopf homolog 4
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