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DLC1 Produkte

(Deleted in Liver Cancer 1 (DLC1))

Kategorien

This gene encodes a GTPase-activating protein (GAP) that is a member of the rhoGAP family of proteins which play a role in the regulation of small GTP-binding proteins. GAP family proteins participate in signaling pathways that regulate cell processes involved in cytoskeletal changes. This gene functions as a tumor suppressor gene in a number of common cancers, including prostate, lung, colorectal, and breast cancers. Multiple transcript variants due to alternative promoters and alternative splicing have been found for this gene.[provided by RefSeq, Apr 2010].

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Ausgewählte DLC1 Kategorien

DLC1 Antikörper

High quality antibodies with extensive validation data.

DLC1 ELISA Kits

Reliable ELISA kits for a wide range of species.

Empfohlene DLC1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse
Applikation IHC, ELISA, IF
Validierungen
  • (1)
  • (5)
Kat. Nr. ABIN185264
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation IHC, WB, ELISA, IF, ICC
Validierungen
  • (3)
Kat. Nr. ABIN6261308
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC (p)
Validierungen
  • (2)
Kat. Nr. ABIN2856359
Menge 100 μL
Datenblatt Datenblatt

Empfohlene DLC1 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6955333
Menge 96 tests
Datenblatt Datenblatt

Empfohlene DLC1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Mouse
Source Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr. ABIN3137440
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren DLC1 Produkten

Muehlich, Hampl, Khalid, Singer, Frank, Breuhahn, Gudermann, Prywes: "The transcriptional coactivators megakaryoblastic leukemia 1/2 mediate the effects of loss of the tumor suppressor deleted in liver cancer 1." in: Oncogene, Vol. 31, Issue 35, pp. 3913-23, (2012) (PubMed).

Li, Vachali, Frederick, Bernstein: "Identification of StARD3 as a lutein-binding protein in the macula of the primate retina." in: Biochemistry, Vol. 50, Issue 13, pp. 2541-9, (2011) (PubMed).

Ko, Yeung, Wong, Chan, Poon, Ng, Yam: "Deleted in liver cancer 1 isoforms are distinctly expressed in human tissues, functionally different and under differential transcriptional regulation in hepatocellular carcinoma." in: Liver international : official journal of the International Association for the Study of the Liver, Vol. 30, Issue 1, pp. 139-48, (2009) (PubMed).

Wilson, McGlinn, Marsh, Evans, Arnold, Wright, Biden, Young, Wainwright, Wicking, Chenevix-Trench: "Sequence variants of DLC1 in colorectal and ovarian tumours." in: Human mutation, Vol. 15, Issue 2, pp. 156-65, (2000) (PubMed).

Sekimata, Kabuyama, Emori, Homma: "Morphological changes and detachment of adherent cells induced by p122, a GTPase-activating protein for Rho." in: The Journal of biological chemistry, Vol. 274, Issue 25, pp. 17757-62, (1999) (PubMed).

Yuan, Miller, Keck, Zimonjic, Thorgeirsson, Popescu: "Cloning, characterization, and chromosomal localization of a gene frequently deleted in human liver cancer (DLC-1) homologous to rat RhoGAP." in: Cancer research, Vol. 58, Issue 10, pp. 2196-9, (1998) (PubMed).

Homma, Emori: "A dual functional signal mediator showing RhoGAP and phospholipase C-delta stimulating activities." in: The EMBO journal, Vol. 14, Issue 2, pp. 286-91, (1995) (PubMed).

Synonyme und alternative Namen zu DLC1

DLC1 Rho GTPase activating protein (DLC1), DLC1 Rho GTPase activating protein S homeolog (dlc1.S), DLC1 Rho GTPase activating protein (dlc1), rho GTPase-activating protein 7 (LOC100456847), deleted in liver cancer 1 (Dlc1), DLC1 Rho GTPase activating protein (Dlc1), rho GTPase-activating protein 7 (LOC100729904), A730069N07Rik, ARHGAP7, Arhgap7, DLC-1, Dlc-1, dlc-1, Dlc1, HP, p122-RhoGAP, RhoGAP, rhogap7, STARD12, StARD12

Bezeichner auf Proteinebene für DLC1

  • Rho-GTPase-activating protein 7
  • START domain-containing protein 12
  • StAR-related lipid transfer (START) domain containing 12
  • deleted in liver cancer 1 protein
  • deleted in liver cancer 1 variant 2
  • rho GTPase-activating protein 7
  • rho-type GTPase-activating protein 7
  • deleted in liver cancer 1
  • deleted in liver cancer 1 protein homolog
  • stAR-related lipid transfer protein 12
  • rho GTPase-activating protein 7-like
  • Deleted in liver cancer 1 protein homolog
  • Rho-type GTPase-activating protein 7
  • p122-RhoGAP
  • dlc-1
  • rho GTPase activating protein 7
  • stARD12
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