DNASE1 Produkte
(Deoxyribonuclease I (DNASE1))
Kategorien
This gene encodes a member of the DNase family. This protein is stored in the zymogen granules of the nuclear envelope and functions by cleaving DNA in an endonucleolytic manner. At least six autosomal codominant alleles have been characterized, DNASE1*1 through DNASE1*6, and the sequence of DNASE1*2 represented in this record. Mutations in this gene have been associated with systemic lupus erythematosus (SLE), an autoimmune disease. A recombinant form of this protein is used to treat the one of the symptoms of cystic fibrosis by hydrolyzing the extracellular DNA in sputum and reducing its viscosity. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008].
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Ausgewählte DNASE1 Kategorien
DNASE1 Antikörper
High quality antibodies with extensive validation data.
DNASE1 ELISA Kits
Reliable ELISA kits for a wide range of species.
DNASE1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene DNASE1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IP, ICC
Validierungen
- (6)
Kat. Nr.
ABIN7433180
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ICC, IF, IHC (p)
Validierungen
- (4)
Kat. Nr.
ABIN2856669
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB
Validierungen
- (4)
Kat. Nr.
ABIN3016215
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene DNASE1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (5)
Kat. Nr.
ABIN6574255
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6966327
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6966325
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene DNASE1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7122635
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1351834
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7505085
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren DNASE1 Produkten
: "Inhibition of nuclease activity by a splice-switching oligonucleotide targeting deoxyribonuclease 1 mRNA prevents apoptosis progression and prolong viability of normal human CD4+ T-lymphocytes." in: Biochimie, Vol. 174, pp. 34-43, (2021) (PubMed).: "Biomarkers of neutrophil extracellular traps (NETs) and nitric oxide-(NO)-dependent oxidative stress in women who miscarried." in: Scientific reports, Vol. 10, Issue 1, pp. 13088, (2020) (PubMed).
: "Low Circulating Levels of Mitochondrial and High Levels of Nuclear DNA Predict Mortality in Chronic Heart Failure." in: Journal of cardiac failure, Vol. 22, Issue 10, pp. 823-8, (2016) (PubMed).
: "Ocular surface extracellular DNA and nuclease activity imbalance: a new paradigm for inflammation in dry eye disease." in: Investigative ophthalmology & visual science, Vol. 53, Issue 13, pp. 8253-63, (2012) (PubMed).
: "Common structural features among monoclonal antibodies binding the same antigenic region of cytochrome c." in: The Journal of biological chemistry, Vol. 266, Issue 4, pp. 2134-42, (1991) (PubMed).
: "A monoclonal antibody specific for a cytochrome c T cell stimulatory peptide inhibits T cell responses and affects the way the peptide associates with antigen-presenting cells." in: European journal of immunology, Vol. 21, Issue 1, pp. 143-51, (1991) (PubMed).
Synonyme und alternative Namen zu DNASE1
DNase I (endA), DNase I (LOC397802), deoxyribonuclease 1 (DNASE1), deoxyribonuclease I (Dnase1), deoxyribonuclease 1 (Dnase1), deoxyribonuclease I L homeolog (dnase1.L), deoxyribonuclease I (dnase1), deoxyribonuclease I (CpipJ_CPIJ011184), deoxyribonuclease I (CpipJ_CPIJ011185), deoxyribonuclease I (CpipJ_CPIJ011186), deoxyribonuclease I (CpipJ_CPIJ011187), deoxyribonuclease I (CpipJ_CPIJ011190), deoxyribonuclease I (CpipJ_CPIJ017803), Deoxyribonuclease I (Desal_1409), deoxyribonuclease I (MPET_RS05255), deoxyribonuclease I (METEV_RS02275), deoxyribonuclease I (Plabr_0631), AI788650, dnase1-A, DNaseI, DNL1, Dnl1, DRNI, LOC397802, zgc:92440Bezeichner auf Proteinebene für DNASE1
- DNase I
- DNase I, lysosomal
- Dornase alfa
- deoxyribonuclease-1
- human urine deoxyribonuclease I
- deoxyribonuclease I
- Deoxyribonuclease I
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