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DNMT3A Produkte

(DNA (Cytosine-5-)-Methyltransferase 3 alpha (DNMT3A))

Kategorien

CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].

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Ausgewählte DNMT3A Kategorien

DNMT3A Antikörper

High quality antibodies with extensive validation data.

DNMT3A ELISA Kits

Reliable ELISA kits for a wide range of species.

DNMT3A Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene DNMT3A Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, IHC (p)
Validierungen
  • (10)
  • (5)
Kat. Nr. ABIN387881
Menge 400 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IP
Validierungen
  • (3)
  • (7)
Kat. Nr. ABIN3022834
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation FACS, IF (cc), IF (p), IHC (p), IHC (fro)
Validierungen
  • (2)
  • (4)
Kat. Nr. ABIN669336
Menge 100 μL
Datenblatt Datenblatt

Empfohlene DNMT3A ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6962647
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6955416
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN1884515
Menge 96 tests
Datenblatt Datenblatt

Empfohlene DNMT3A Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (1)
  • (2)
Kat. Nr. ABIN2719617
Menge 20 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7122679
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1351868
Menge 10 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren DNMT3A Produkten

van Mierlo, Dirks, De Clerck, Brinkman, Huth, Kloet, Saksouk, Kroeze, Willems, Farlik, Bock, Jansen, Deforce, Vermeulen, Déjardin, Dhaenens, Marks: "Integrative Proteomic Profiling Reveals PRC2-Dependent Epigenetic Crosstalk Maintains Ground-State Pluripotency." in: Cell stem cell, Vol. 24, Issue 1, pp. 123-137.e8, (2019) (PubMed).

Heyn, Logan, Fluteau, Challis, Auchynnikava, Martin, Marsh, Taglini, Kilanowski, Parry, Cormier-Daire, Fong, Gibson, Hwa, Ibáñez, Robertson, Sebastiani, Rappsilber, Allshire, Reijns, Dauber, Sproul et al.: "Gain-of-function DNMT3A mutations cause microcephalic dwarfism and hypermethylation of Polycomb-regulated regions. ..." in: Nature genetics, Vol. 51, Issue 1, pp. 96-105, (2019) (PubMed).

Cyphert, Walker, Hang, Dhawan, Haliyur, Bonatakis, Avrahami, Brissova, Kaestner, Bhushan, Powers, Stein: "Examining How the MAFB Transcription Factor Affects Islet β-Cell Function Postnatally." in: Diabetes, Vol. 68, Issue 2, pp. 337-348, (2019) (PubMed).

Yang, Wu, Li, Gao, Yang, Li, Kong: "The triterpenoid corosolic acid blocks transformation and epigenetically reactivates Nrf2 in TRAMP-C1 prostate cells." in: Molecular carcinogenesis, (2018) (PubMed).

La, Mäkelä, Chan, Rossello, Nefzger, Legrand, De Seram, Polo, Hobbs: "Identification of dynamic undifferentiated cell states within the male germline." in: Nature communications, Vol. 9, Issue 1, pp. 2819, (2018) (PubMed).

ODoherty, OShea, Sandra, Lonergan, Fair, Forde: "Imprinted and DNA methyltransferase gene expression in the endometrium during the pre- and peri-implantation period in cattle." in: Reproduction, fertility, and development, Vol. 29, Issue 9, pp. 1729-1738, (2018) (PubMed).

Chatterjee, Lin, Chen, Peng, Wu, Tseng, Chen, Shen: "DNA Demethylation by DNMT3A and DNMT3B in vitro and of Methylated Episomal DNA in Transiently Transfected Cells." in: Biochimica et biophysica acta. Gene regulatory mechanisms, Vol. 1861, Issue 11, pp. 1048-1061, (2018) (PubMed).

Pang, Liu, Li, Xiao, Wang, Yang, Li, Tang, Qin, Du, Zhang, Liu, Sun, Ren: "MYC and DNMT3A-mediated DNA methylation represses microRNA-200b in triple negative breast cancer." in: Journal of cellular and molecular medicine, Vol. 22, Issue 12, pp. 6262-6274, (2018) (PubMed).

Neri, Rapelli, Krepelova, Incarnato, Parlato, Basile, Maldotti, Anselmi, Oliviero: "Intragenic DNA methylation prevents spurious transcription initiation." in: Nature, Vol. 543, Issue 7643, pp. 72-77, (2017) (PubMed).

Acharya, Baddour, Kawashita, Allen, Syage, Nguyen, Yoon, Giedzinski, Yu, Parihar, Baulch: "Epigenetic determinants of space radiation-induced cognitive dysfunction." in: Scientific reports, Vol. 7, pp. 42885, (2017) (PubMed).

Synonyme und alternative Namen zu DNMT3A

DNA methyltransferase 3 alpha (DNMT3A), DNA methyltransferase 3A (Dnmt3a), DNA methyltransferase 3 alpha (Dnmt3a), DNA methyltransferase 3 alpha (dnmt3a), DNA (cytosine-5-)-methyltransferase 3 alpha b (dnmt3ab), DNMT3A, dnmt3a1, DNMT3A2, dnmt6, M.HsaIIIA, MmuIIIA

Bezeichner auf Proteinebene für DNMT3A

  • DNA (cytosine-5)-methyltransferase 3A
  • DNA cytosine methyltransferase 3 alpha
  • DNA (cytosine-5-)-methyltransferase 3 alpha
  • DNA MTase HsaIIIA
  • DNA cytosine methyltransferase 3A2
  • DNA methyltransferase 3A
  • DNA methyl transferase alpha
  • DNA-methyltransferase 3a
  • DNA MTase MmuIIIA
  • DNA methyltransferase MmuIIIA
  • LOW QUALITY PROTEIN: DNA (cytosine-5)-methyltransferase 3A
  • DNA (cytosine-5-)-methyltransferase 6
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