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DOK2 Produkte

(DOK2)
The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells. [provided by RefSeq, Jul 2008].

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Ausgewählte DOK2 Kategorien

DOK2 Antikörper

High quality antibodies with extensive validation data.

DOK2 ELISA Kits

Reliable ELISA kits for a wide range of species.

DOK2 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene DOK2 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC, IF
Validierungen
  • (3)
Kat. Nr. ABIN7150566
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human, Mouse
Applikation WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validierungen
  • (3)
Kat. Nr. ABIN684148
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IF, ICC
Validierungen
  • (3)
Kat. Nr. ABIN2854341
Menge 100 μL
Datenblatt Datenblatt

Empfohlene DOK2 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse
Analytical Method Qualitative Cell ELISA
Validierungen
Kat. Nr. ABIN1380557
Menge 2 x 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN5593715
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Cow
Analytical Method
Validierungen
Kat. Nr. ABIN1130515
Menge 96 tests
Datenblatt Datenblatt

Empfohlene DOK2 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1351902
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr. ABIN3078950
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Mouse
Source Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr. ABIN3132011
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren DOK2 Produkten

Honma, Higuchi, Shirakata, Yasuda, Shibuya, Iemura, Natsume, Yamanashi: "Dok-3 sequesters Grb2 and inhibits the Ras-Erk pathway downstream of protein-tyrosine kinases." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 11, Issue 2, pp. 143-51, (2006) (PubMed).

Salomon, Ficarro, Brill, Brinker, Phung, Ericson, Sauer, Brock, Horn, Schultz, Peters: "Profiling of tyrosine phosphorylation pathways in human cells using mass spectrometry." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 2, pp. 443-8, (2003) (PubMed).

Cong, Yuan, Goff: "Characterization of a novel member of the DOK family that binds and modulates Abl signaling." in: Molecular and cellular biology, Vol. 19, Issue 12, pp. 8314-25, (2000) (PubMed).

Schaeper, Gehring, Fuchs, Sachs, Kempkes, Birchmeier: "Coupling of Gab1 to c-Met, Grb2, and Shp2 mediates biological responses." in: The Journal of cell biology, Vol. 149, Issue 7, pp. 1419-32, (2000) (PubMed).

Di Cristofano, Carpino, Dunant, Friedland, Kobayashi, Strife, Wisniewski, Clarkson, Pandolfi, Resh: "Molecular cloning and characterization of p56dok-2 defines a new family of RasGAP-binding proteins." in: The Journal of biological chemistry, Vol. 273, Issue 9, pp. 4827-30, (1998) (PubMed).

Jones, Dumont: "The Tek/Tie2 receptor signals through a novel Dok-related docking protein, Dok-R." in: Oncogene, Vol. 17, Issue 9, pp. 1097-108, (1998) (PubMed).

Nelms, Snow, Hu-Li, Paul: "FRIP, a hematopoietic cell-specific rasGAP-interacting protein phosphorylated in response to cytokine stimulation." in: Immunity, Vol. 9, Issue 1, pp. 13-24, (1998) (PubMed).

Synonyme und alternative Namen zu DOK2

docking protein 2 (DOK2), docking protein 2 (Dok2), Dok-2, DokR, Frip, p56DOK, p56dok-2

Bezeichner auf Proteinebene für DOK2

  • IL-Four Receptor Interacting Protein
  • IL-four receptor-interacting protein
  • dok-R
  • dok-related protein
  • downstream of tyrosine kinase 2
  • p56 dok-2
  • p56(dok-2)
  • docking protein 2
  • Downstream of tyrosine kinase 2
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