Doublecortin Produkte
(Doublecortin (DCX))
Kategorien
This gene encodes a member of the doublecortin family. The protein encoded by this gene is a cytoplasmic protein and contains two doublecortin domains, which bind microtubules. In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. The encoded protein appears to direct neuronal migration by regulating the organization and stability of microtubules. In addition, the encoded protein interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex. Mutations in this gene cause abnormal migration of neurons during development and disrupt the layering of the cortex, leading to epilepsy, mental retardation, subcortical band heterotopia ('double cortex' syndrome) in females and lissencephaly ('smooth brain' syndrome) in males. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2010].
antibodies-online.com steht für hochwertige Forschungsprodukte. Suchen, finden und bestellen Sie Tools mit umfangreichen Validierungsdaten, Bildern, Referenzen. Unser wissenschaftlicher Kundenservice steht Ihnen jederzeit zur Verfügung, wenn Sie Fragen zur Auswahl oder Anwendung unserer Produkte haben.
Ausgewählte Doublecortin Kategorien
Doublecortin Antikörper
High quality antibodies with extensive validation data.
Doublecortin ELISA Kits
Reliable ELISA kits for a wide range of species.
Doublecortin Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene Doublecortin Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC, ICC, FACS
Validierungen
- (1)
- (7)
Kat. Nr.
ABIN969513
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, ELISA, IHC, IF
Validierungen
- (5)
Kat. Nr.
ABIN625829
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC, FACS, IF/ICC
Validierungen
- (8)
Kat. Nr.
ABIN1844030
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene Doublecortin ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6955452
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6955453
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6955454
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene Doublecortin Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN1351244
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7122702
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Rat
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7396373
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren Doublecortin Produkten
: "Regulation of the p75 neurotrophin receptor attenuates neuroinflammation and stimulates hippocampal neurogenesis in experimental Streptococcus pneumoniae meningitis." in: Journal of neuroinflammation, Vol. 18, Issue 1, pp. 253, (2022) (PubMed).: "LC-MS/MS identification of doublecortin as abundant beta cell-selective protein discharged by damaged beta cells in vitro." in: Journal of proteomics, Vol. 80, pp. 268-80, (2013) (PubMed).
: "Properties of doublecortin-(DCX)-expressing cells in the piriform cortex compared to the neurogenic dentate gyrus of adult mice." in: PLoS ONE, Vol. 6, Issue 10, pp. e25760, (2011) (PubMed).
: "Granulocyte colony-stimulating factor increases the therapeutic efficacy of bone marrow mononuclear cell transplantation in cerebral ischemia in mice." in: BMC neuroscience, Vol. 12, pp. 61, (2011) (PubMed).
: "MiR-128 up-regulation inhibits Reelin and DCX expression and reduces neuroblastoma cell motility and invasiveness." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 23, Issue 12, pp. 4276-87, (2009) (PubMed).
: "The location of DCX mutations predicts malformation severity in X-linked lissencephaly." in: Neurogenetics, Vol. 9, Issue 4, pp. 277-85, (2008) (PubMed).
: "Doublecortin is expressed in articular chondrocytes." in: Biochemical and biophysical research communications, Vol. 363, Issue 3, pp. 694-700, (2007) (PubMed).
: "Induction of neurogenesis in the neocortex of adult mice." in: Nature, Vol. 405, Issue 6789, pp. 951-5, (2000) (PubMed).
: "A novel CNS gene required for neuronal migration and involved in X-linked subcortical laminar heterotopia and lissencephaly syndrome." in: Cell, Vol. 92, Issue 1, pp. 51-61, (1998) (PubMed).
: "Doublecortin, a brain-specific gene mutated in human X-linked lissencephaly and double cortex syndrome, encodes a putative signaling protein." in: Cell, Vol. 92, Issue 1, pp. 63-72, (1998) (PubMed).
Synonyme und alternative Namen zu Doublecortin
doublecortin (DCX), doublecortin (Dcx), 18C15.5, DBCN, Dbct, DC, DCX, LISX, SCLH, XLISBezeichner auf Proteinebene für Doublecortin
- doublecortex; lissencephaly, X-linked (doublecortin)
- doublecortin
- doublecortex
- doublin
- lis-X
- lissencephalin-X
- neuronal migration protein doublecortin
- lissencephaly, X-linked (doublecortin)
Haben Sie etwas anderes gesucht?
Sie sind hier:
