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DPF3 Produkte

(D4, Zinc and Double PHD Fingers, Family 3 (DPF3))

Kategorien

Muscle-specific component of the BAF complex, a multiprotein complex involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Specifically binds acetylated lysines on histone 3 and 4 (H3K14ac, H3K9ac, H4K5ac, H4K8ac, H4K12ac, H4K16ac). In the complex, it acts as a tissue-specific anchor between histone acetylations and methylations and chromatin remodeling. It thereby probably plays an essential role in heart and skeletal muscle development (By similarity). Belongs to the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth.

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Ausgewählte DPF3 Kategorien

DPF3 Antikörper

High quality antibodies with extensive validation data.

DPF3 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene DPF3 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Applikation WB
Validierungen
  • (2)
  • (4)
Kat. Nr. ABIN2775708
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Applikation WB, IHC
Validierungen
  • (1)
  • (2)
Kat. Nr. ABIN2775709
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Mouse
Applikation WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC
Validierungen
  • (1)
Kat. Nr. ABIN5675567
Menge 100 μL
Datenblatt Datenblatt

Empfohlene DPF3 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr. ABIN3092223
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Mouse
Source Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr. ABIN3134531
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Zebrafish (Danio rerio)
Source Yeast
Validierungen
Kat. Nr. ABIN1655185
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren DPF3 Produkten

Theodorou, Speletas, Mamara, Papachristopoulou, Lazou, Scorilas, Katsantoni: "Identification of a STAT5 target gene, Dpf3, provides novel insights in chronic lymphocytic leukemia." in: PLoS ONE, Vol. 8, Issue 10, pp. e76155, (2013) (PubMed).

Hoyal, Kammerer, Roth, Reneland, Marnellos, Kiechle, Schwarz-Boeger, Griffiths, Ebner, Rehbock, Nelson, Braun: "Genetic polymorphisms in DPF3 associated with risk of breast cancer and lymph node metastases." in: Journal of carcinogenesis, Vol. 4, pp. 13, (2005) (PubMed).

Synonyme und alternative Namen zu DPF3

double PHD fingers 3 (DPF3), D4, zinc and double PHD fingers, family 3 (Dpf3), double PHD fingers 3 (Dpf3), D4, zinc and double PHD fingers, family 3 (dpf3), 2810403B03Rik, 6530402L11Rik, BAF45C, C78788, cer-d4, CERD4, si:ch211-268e23.1, wu:fj43h12

Bezeichner auf Proteinebene für DPF3

  • cer-d4
  • zinc finger protein DPF3
  • zinc finger protein cer-d4
  • BRG1-associated factor 45C
  • D4 zinc and double PHD finger family 3
  • cerebellum D4
  • D4 zinc and double PHD fingers family 3 protein
  • fj43h12
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