DR3/LARD Produkte
(Tumor Necrosis Factor Receptor Superfamily, Member 25 (TNFRSF25))
Kategorien
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed preferentially in the tissues enriched in lymphocytes, and it may play a role in regulating lymphocyte homeostasis. This receptor has been shown to stimulate NF-kappa B activity and regulate cell apoptosis. The signal transduction of this receptor is mediated by various death domain containing adaptor proteins. Knockout studies in mice suggested the role of this gene in the removal of self-reactive T cells in the thymus. Multiple alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported, most of which are potentially secreted molecules. The alternative splicing of this gene in B and T cells encounters a programmed change upon T-cell activation, which predominantly produces full-length, membrane bound isoforms, and is thought to be involved in controlling lymphocyte proliferation induced by T-cell activation. [provided by RefSeq, Jul 2008].
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Ausgewählte DR3/LARD Kategorien
DR3/LARD Antikörper
High quality antibodies with extensive validation data.
DR3/LARD ELISA Kits
Reliable ELISA kits for a wide range of species.
DR3/LARD Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene DR3/LARD Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, FACS, IHC
Validierungen
- (6)
Kat. Nr.
ABIN7193676
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validierungen
- (1)
- (3)
Kat. Nr.
ABIN668421
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IF
Validierungen
- (3)
Kat. Nr.
ABIN7271071
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene DR3/LARD ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6973621
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN5526791
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN5510736
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene DR3/LARD Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse
Source
HEK-293 Cells
Validierungen
- (2)
Kat. Nr.
ABIN7274495
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1323193
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (1)
Kat. Nr.
ABIN7092807
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren DR3/LARD Produkten
: "TL1A as a potential local inducer of IL17A Expression in colon mucosa of inflammatory bowel disease patients." in: Scandinavian journal of immunology, (2015) (PubMed).: "Expression and function of the TL1A/DR3 axis in chronic lymphocytic leukemia." in: Oncotarget, Vol. 6, Issue 31, pp. 32061-74, (2015) (PubMed).
: "The TNF-family cytokine TL1A inhibits proliferation of human activated B cells." in: PLoS ONE, Vol. 8, Issue 4, pp. e60136, (2013) (PubMed).
: "Mechanisms of the apoptosis induced by CD176 antibody in human leukemic cells." in: International journal of oncology, Vol. 38, Issue 6, pp. 1565-73, (2011) (PubMed).
: "Naive and activated T cells display differential responsiveness to TL1A that affects Th17 generation, maintenance, and proliferation." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 25, Issue 1, pp. 409-19, (2011) (PubMed).
: "Survival advantages conferred to colon cancer cells by E-selectin-induced activation of the PI3K-NFκB survival axis downstream of Death receptor-3." in: BMC cancer, Vol. 11, pp. 285, (2011) (PubMed).
: "TL1A induces the expression of TGF-β-inducible gene h3 (βig-h3) through PKC, PI3K, and ERK in THP-1 cells." in: Cellular immunology, Vol. 266, Issue 1, pp. 61-6, (2010) (PubMed).
: "Soluble decoy receptor 3 induces angiogenesis by neutralization of TL1A, a cytokine belonging to tumor necrosis factor superfamily and exhibiting angiostatic action." in: Cancer research, Vol. 64, Issue 3, pp. 1122-9, (2004) (PubMed).
: "Stable and unstable pools of Myc protein exist in human cells." in: Oncogene, Vol. 21, Issue 55, pp. 8515-20, (2002) (PubMed).
: "Multiple pathways of TWEAK-induced cell death." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 168, Issue 2, pp. 734-43, (2002) (PubMed).
Synonyme und alternative Namen zu DR3/LARD
TNF receptor superfamily member 25 (TNFRSF25), tumor necrosis factor receptor superfamily, member 25 (Tnfrsf25), TNF receptor superfamily member 25 (Tnfrsf25), APO-3, DDR3, DR3, LARD, TNFRSF12, Tnfrsf12, TNFRSF25, TR3, TRAMP, Wsl, WSL-1, WSL-LRBezeichner auf Proteinebene für DR3/LARD
- apoptosis inducing receptor
- apoptosis-inducing receptor AIR
- apoptosis-mediating receptor DR3
- apoptosis-mediating receptor TRAMP
- death domain receptor 3 soluble form
- death receptor beta
- lymphocyte-associated receptor of death
- protein WSL-1
- tumor necrosis factor receptor superfamily member 25
- tumor necrosis factor receptor superfamily, member 12 (translocating chain-association membrane protein)
- tumor necrosis factor receptor superfamily, member 12
- tumor necrosis factor receptor superfamily, member 25
- translocating chain-association membrane protein
- tumor necrosis factor receptor superfamily, member12
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