DUSP1 Produkte
(Dual Specificity Phosphatase 1 (DUSP1))
Kategorien
The expression of DUSP1 gene is induced in human skin fibroblasts by oxidative/heat stress and growth factors. It specifies a protein with structural features similar to members of the non-receptor-type protein-tyrosine phosphatase family, and which has significant amino-acid sequence similarity to a Tyr/Ser-protein phosphatase encoded by the late gene H1 of vaccinia virus. The bacterially expressed and purified DUSP1 protein has intrinsic phosphatase activity, and specifically inactivates mitogen-activated protein (MAP) kinase in vitro by the concomitant dephosphorylation of both its phosphothreonine and phosphotyrosine residues. Furthermore, it suppresses the activation of MAP kinase by oncogenic ras in extracts of Xenopus oocytes. Thus, DUSP1 may play an important role in the human cellular response to environmental stress as well as in the negative regulation of cellular proliferation. [provided by RefSeq, Jul 2008].
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Ausgewählte DUSP1 Kategorien
DUSP1 Antikörper
High quality antibodies with extensive validation data.
DUSP1 ELISA Kits
Reliable ELISA kits for a wide range of species.
DUSP1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene DUSP1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC
Validierungen
- (5)
Kat. Nr.
ABIN184638
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validierungen
- (3)
- (3)
Kat. Nr.
ABIN735368
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IF
Validierungen
- (1)
- (3)
Kat. Nr.
ABIN515099
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene DUSP1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6955464
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6955465
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Qualitative Cell ELISA
Validierungen
Kat. Nr.
ABIN1381321
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene DUSP1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1352094
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1352096
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7396922
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren DUSP1 Produkten
: "Induction of Mkp-1 and Nuclear Translocation of Nrf2 by Limonoids from Khaya grandifoliola C.DC Protect L-02 Hepatocytes against Acetaminophen-Induced Hepatotoxicity." in: Frontiers in pharmacology, Vol. 8, pp. 653, (2017) (PubMed).: "Connexin 32 dysfunction promotes ethanol-related hepatocarcinogenesis via activation of Dusp1-Erk axis." in: Oncotarget, Vol. 7, Issue 2, pp. 2009-21, (2016) (PubMed).
: "Transduction of Functionally Contrasting Signals by Two Mycobacterial PPE Proteins Downstream of TLR2 Receptors." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 197, Issue 5, pp. 1776-87, (2016) (PubMed).
: "Growth Hormone Releasing Peptide-2 Attenuation of Protein Kinase C-Induced Inflammation in Human Ovarian Granulosa Cells." in: International journal of molecular sciences, Vol. 17, Issue 8, (2016) (PubMed).
: "MAP kinase phosphatase DUSP1 is overexpressed in human obese and modulated by physical activity." in: American journal of physiology. Endocrinology and metabolism, pp. ajpendo.00577.2013, (2014) (PubMed).
: "Progesterone receptor inhibits proliferation of human breast cancer cells via induction of MAPK phosphatase 1 (MKP-1/DUSP1)." in: The Journal of biological chemistry, Vol. 286, Issue 50, pp. 43091-102, (2011) (PubMed).
: "Glucocorticoid receptor-induced MAPK phosphatase-1 (MPK-1) expression inhibits paclitaxel-associated MAPK activation and contributes to breast cancer cell survival." in: The Journal of biological chemistry, Vol. 280, Issue 6, pp. 4117-24, (2005) (PubMed).
: "Role of CL-100, a dual specificity phosphatase, in thrombin-induced endothelial cell activation." in: The Journal of biological chemistry, Vol. 279, Issue 45, pp. 46678-85, (2004) (PubMed).
: "Evidence that mitogen-activated protein kinase phosphatase-1 induction by proteasome inhibitors plays an antiapoptotic role." in: Molecular pharmacology, Vol. 66, Issue 6, pp. 1478-90, (2004) (PubMed).
: "The human CL100 gene encodes a Tyr/Thr-protein phosphatase which potently and specifically inactivates MAP kinase and suppresses its activation by oncogenic ras in Xenopus oocyte extracts." in: Oncogene, Vol. 8, Issue 7, pp. 2015-20, (1993) (PubMed).
Synonyme und alternative Namen zu DUSP1
dual specificity phosphatase 1 (DUSP1), dual specificity phosphatase 1 (Dusp1), dual specificity phosphatase 1 (dusp1), dual specificity phosphatase 1 S homeolog (dusp1.S), 3CH134, cb269, CL100, DUSP1, erp, HVH1, id:ibd2586, MKP-1, mkp-1, MKP1, Mkp1, PTPN10, Ptpn16, sb:cb269, U19515, wu:fd19g02, wu:fe50g09, XCL100, zgc:55920Bezeichner auf Proteinebene für DUSP1
- MAP kinase phosphatase 1
- dual specificity protein phosphatase 1
- dual specificity protein phosphatase hVH1
- mitogen-activated protein kinase phosphatase 1
- protein-tyrosine phosphatase CL100
- serine/threonine specific protein phosphatase
- 3CH134/CL100 PTPase
- MAP kinase phosphatase-1
- mitogen-activated protein (MAP) kinase phosphatase-1
- oxidative stress-inducible protein tyrosine phosphatase
- protein tyrosine phosphatase non-receptor type 16
- protein tyrosine phosphatase, non-receptor type 16
- protein-tyrosine phosphatase non-receptor type 16
- dual specificity phosphatase 1
- mitogen-activated protein kinase phosphatase-1
- protein-tyrosine phosphatase 3CH134
- protein-tyrosine phosphatase ERP
- mkp-1
- MAPK phosphatase 1
- LOW QUALITY PROTEIN: dual specificity protein phosphatase 1
- MAP kinase phosphatase XCL100(beta) protein
- XCL100-beta
- dual specificity protein phosphatase 1-B
- dusp1-b
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