DUSP12 Produkte
(Dual Specificity Phosphatase 12 (DUSP12))
Kategorien
The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is the human ortholog of the Saccharomyces cerevisiae YVH1 protein tyrosine phosphatase. It is localized predominantly in the nucleus, and is novel in that it contains, and is regulated by a zinc finger domain. [provided by RefSeq, Jul 2008].
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Ausgewählte DUSP12 Kategorien
DUSP12 Antikörper
High quality antibodies with extensive validation data.
DUSP12 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene DUSP12 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IP, IF
Validierungen
- (3)
Kat. Nr.
ABIN524689
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB
Validierungen
- (2)
Kat. Nr.
ABIN524688
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB
Validierungen
- (1)
Kat. Nr.
ABIN1537912
Menge
400 μL
Datenblatt
Datenblatt
Empfohlene DUSP12 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1352104
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1352106
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3079207
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren DUSP12 Produkten
: "Dual-specificity phosphatases: critical regulators with diverse cellular targets." in: The Biochemical journal, Vol. 418, Issue 3, pp. 475-89, (2009) (PubMed).: "Targeting dual-specificity phosphatases: manipulating MAP kinase signalling and immune responses." in: Nature reviews. Drug discovery, Vol. 6, Issue 5, pp. 391-403, (2007) (PubMed).
: "Characterization of rat LECAM-1 (L-selectin) by the use of monoclonal antibodies and evidence for the presence of soluble LECAM-1 in rat sera." in: European journal of immunology, Vol. 23, Issue 9, pp. 2181-8, (1993) (PubMed).
Synonyme und alternative Namen zu DUSP12
dual specificity phosphatase 12 (DUSP12), dual specificity phosphatase 12 (dusp12), dual specificity phosphatase 12 L homeolog (dusp12.L), Dual specificity protein phosphatase 12 (GL50803_36315), dual specificity protein phosphatase 12 (MGYG_01770), dual specificity phosphatase 12 (Dusp12), 1190004O14Rik, AA027408, AW049275, DUSP1, DUSP12, dusp12, ESTM36, GKAP, LMW-DSP4, MGC154526, mVH1, T-DSP4, VH1, YVH1, zgc:114069Bezeichner auf Proteinebene für DUSP12
- dual specificity phosphatase 12
- dual specificity protein phosphatase 12
- Dual specificity protein phosphatase 12
- dual specificity protein phosphatase 12-like
- YVH1 protein-tyrosine phosphatase ortholog
- dual specificity tyrosine phosphatase YVH1
- serine/threonine specific protein phosphatase
- dual specificity phosphatase T-DSP4
- dual specificity phosphatase VH1
- glucokinase-associated dual specificity phosphatase
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