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DUSP12 Produkte

(Dual Specificity Phosphatase 12 (DUSP12))

Kategorien

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is the human ortholog of the Saccharomyces cerevisiae YVH1 protein tyrosine phosphatase. It is localized predominantly in the nucleus, and is novel in that it contains, and is regulated by a zinc finger domain. [provided by RefSeq, Jul 2008].

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Ausgewählte DUSP12 Kategorien

DUSP12 Antikörper

High quality antibodies with extensive validation data.

DUSP12 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene DUSP12 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IP, IF
Validierungen
  • (3)
Kat. Nr. ABIN524689
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB
Validierungen
  • (2)
Kat. Nr. ABIN524688
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human, Mouse
Applikation WB
Validierungen
  • (1)
Kat. Nr. ABIN1537912
Menge 400 μL
Datenblatt Datenblatt

Empfohlene DUSP12 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1352104
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1352106
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr. ABIN3079207
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren DUSP12 Produkten

Patterson, Brummer, OBrien, Daly: "Dual-specificity phosphatases: critical regulators with diverse cellular targets." in: The Biochemical journal, Vol. 418, Issue 3, pp. 475-89, (2009) (PubMed).

Jeffrey, Camps, Rommel, Mackay: "Targeting dual-specificity phosphatases: manipulating MAP kinase signalling and immune responses." in: Nature reviews. Drug discovery, Vol. 6, Issue 5, pp. 391-403, (2007) (PubMed).

Tamatani, Kitamura, Kuida, Shirao, Mochizuki, Suematsu, Schmid-Schönbein, Watanabe, Tsurufuji, Miyasaka: "Characterization of rat LECAM-1 (L-selectin) by the use of monoclonal antibodies and evidence for the presence of soluble LECAM-1 in rat sera." in: European journal of immunology, Vol. 23, Issue 9, pp. 2181-8, (1993) (PubMed).

Synonyme und alternative Namen zu DUSP12

dual specificity phosphatase 12 (DUSP12), dual specificity phosphatase 12 (dusp12), dual specificity phosphatase 12 L homeolog (dusp12.L), Dual specificity protein phosphatase 12 (GL50803_36315), dual specificity protein phosphatase 12 (MGYG_01770), dual specificity phosphatase 12 (Dusp12), 1190004O14Rik, AA027408, AW049275, DUSP1, DUSP12, dusp12, ESTM36, GKAP, LMW-DSP4, MGC154526, mVH1, T-DSP4, VH1, YVH1, zgc:114069

Bezeichner auf Proteinebene für DUSP12

  • dual specificity phosphatase 12
  • dual specificity protein phosphatase 12
  • Dual specificity protein phosphatase 12
  • dual specificity protein phosphatase 12-like
  • YVH1 protein-tyrosine phosphatase ortholog
  • dual specificity tyrosine phosphatase YVH1
  • serine/threonine specific protein phosphatase
  • dual specificity phosphatase T-DSP4
  • dual specificity phosphatase VH1
  • glucokinase-associated dual specificity phosphatase
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