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DUSP8 Produkte

(Dual Specificity Phosphatase 8 (DUSP8))

Kategorien

The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates SAPK/JNK and p38, is expressed predominantly in the adult brain, heart, and skeletal muscle, is localized in the cytoplasm, and is induced by nerve growth factor and insulin. An intronless pseudogene for DUSP8 is present on chromosome 10q11.2. [provided by RefSeq, Jul 2008].

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Ausgewählte DUSP8 Kategorien

DUSP8 Antikörper

High quality antibodies with extensive validation data.

DUSP8 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene DUSP8 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse
Applikation WB, ELISA, IHC
Validierungen
  • (3)
Kat. Nr. ABIN7242101
Menge 200 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IF
Validierungen
  • (3)
Kat. Nr. ABIN7266849
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC (p)
Validierungen
  • (2)
Kat. Nr. ABIN392868
Menge 400 μL
Datenblatt Datenblatt

Empfohlene DUSP8 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1352144
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr. ABIN3079104
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Mouse
Source Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr. ABIN3131391
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren DUSP8 Produkten

Smeeton, Dhir, Hu, Feeney, Chen, Rosenblum: "Integrin-linked Kinase Controls Renal Branching Morphogenesis via Dual Specificity Phosphatase 8." in: Journal of the American Society of Nephrology : JASN, Vol. 27, Issue 5, pp. 1465-77, (2016) (PubMed).

Berger, Buschbeck, Bange, Ullrich: "Identification of a transcriptionally active hVH-5 pseudogene on 10q22.2." in: Cancer genetics and cytogenetics, Vol. 159, Issue 2, pp. 155-9, (2005) (PubMed).

Martell, Seasholtz, Kwak, Clemens, Dixon: "hVH-5: a protein tyrosine phosphatase abundant in brain that inactivates mitogen-activated protein kinase." in: Journal of neurochemistry, Vol. 65, Issue 4, pp. 1823-33, (1995) (PubMed).

Synonyme und alternative Namen zu DUSP8

dual specificity phosphatase 8 (DUSP8), dual specificity phosphatase 8 (dusp8), dual specificity phosphatase 8a (dusp8a), dual specificity protein phosphatase 8 (DSP8), dual specificity phosphatase 8 (Dusp8), dual specificity protein phosphatase 8 (LOC615727), 5530400B01Rik, AI593498, C11orf81, DUSP8, HB5, Hb5, HVH-5, HVH8, M3/6, Nttp1, zgc:77593

Bezeichner auf Proteinebene für DUSP8

  • dual specificity phosphatase 8
  • dual specificity protein phosphatase 8-like
  • dual specificity protein phosphatase 8
  • H1 phosphatase, vaccinia virus homolog
  • dual specificity protein phosphatase hVH-5
  • serine/threonine specific protein phosphatase
  • neuronal tyrosine threonine phosphatase 1
  • neuronal tyrosine/threonine phosphatase 1
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