DUSP8 Produkte
(Dual Specificity Phosphatase 8 (DUSP8))
Kategorien
The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates SAPK/JNK and p38, is expressed predominantly in the adult brain, heart, and skeletal muscle, is localized in the cytoplasm, and is induced by nerve growth factor and insulin. An intronless pseudogene for DUSP8 is present on chromosome 10q11.2. [provided by RefSeq, Jul 2008].
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Ausgewählte DUSP8 Kategorien
DUSP8 Antikörper
High quality antibodies with extensive validation data.
DUSP8 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene DUSP8 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, ELISA, IHC
Validierungen
- (3)
Kat. Nr.
ABIN7242101
Menge
200 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IF
Validierungen
- (3)
Kat. Nr.
ABIN7266849
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC (p)
Validierungen
- (2)
Kat. Nr.
ABIN392868
Menge
400 μL
Datenblatt
Datenblatt
Empfohlene DUSP8 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1352144
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3079104
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3131391
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren DUSP8 Produkten
: "Integrin-linked Kinase Controls Renal Branching Morphogenesis via Dual Specificity Phosphatase 8." in: Journal of the American Society of Nephrology : JASN, Vol. 27, Issue 5, pp. 1465-77, (2016) (PubMed).: "Identification of a transcriptionally active hVH-5 pseudogene on 10q22.2." in: Cancer genetics and cytogenetics, Vol. 159, Issue 2, pp. 155-9, (2005) (PubMed).
: "hVH-5: a protein tyrosine phosphatase abundant in brain that inactivates mitogen-activated protein kinase." in: Journal of neurochemistry, Vol. 65, Issue 4, pp. 1823-33, (1995) (PubMed).
Synonyme und alternative Namen zu DUSP8
dual specificity phosphatase 8 (DUSP8), dual specificity phosphatase 8 (dusp8), dual specificity phosphatase 8a (dusp8a), dual specificity protein phosphatase 8 (DSP8), dual specificity phosphatase 8 (Dusp8), dual specificity protein phosphatase 8 (LOC615727), 5530400B01Rik, AI593498, C11orf81, DUSP8, HB5, Hb5, HVH-5, HVH8, M3/6, Nttp1, zgc:77593Bezeichner auf Proteinebene für DUSP8
- dual specificity phosphatase 8
- dual specificity protein phosphatase 8-like
- dual specificity protein phosphatase 8
- H1 phosphatase, vaccinia virus homolog
- dual specificity protein phosphatase hVH-5
- serine/threonine specific protein phosphatase
- neuronal tyrosine threonine phosphatase 1
- neuronal tyrosine/threonine phosphatase 1
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