E2F1 Produkte
(E2F Transcription Factor 1 (E2F1))
Kategorien
The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F2 and E2F3, have an additional cyclin binding domain. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can mediate both cell proliferation and p53-dependent/independent apoptosis. [provided by RefSeq, Jul 2008].
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Ausgewählte E2F1 Kategorien
E2F1 Antikörper
High quality antibodies with extensive validation data.
E2F1 ELISA Kits
Reliable ELISA kits for a wide range of species.
E2F1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene E2F1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC, FACS
Validierungen
- (4)
- (6)
Kat. Nr.
ABIN969516
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC, FACS, IF
Validierungen
- (5)
Kat. Nr.
ABIN7127462
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, PLA
Validierungen
- (5)
Kat. Nr.
ABIN560676
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene E2F1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6955489
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Analytical Method
Qualitative Cell ELISA
Validierungen
Kat. Nr.
ABIN1380168
Menge
2 x 96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative
Validierungen
Kat. Nr.
ABIN773114
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene E2F1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1352229
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN2719894
Menge
20 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7409272
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren E2F1 Produkten
: "Comparison of the therapeutic effects of lobaplatin and carboplatin on retinoblastoma in vitro and in vivo." in: International journal of oncology, Vol. 57, Issue 3, pp. 697-706, (2020) (PubMed).: "Long-term PGC1β overexpression leads to apoptosis, autophagy and muscle wasting." in: Scientific reports, Vol. 7, Issue 1, pp. 10237, (2019) (PubMed).
: "The Natural Compound Neobractatin Induces Cell Cycle Arrest by Regulating E2F1 and Gadd45α." in: Frontiers in oncology, Vol. 9, pp. 654, (2019) (PubMed).
: "Silica nanoparticle exposure inducing granulosa cell apoptosis and follicular atresia in female Balb/c mice." in: Environmental science and pollution research international, Vol. 25, Issue 4, pp. 3423-3434, (2018) (PubMed).
: "Gambogic acid sensitizes gemcitabine efficacy in pancreatic cancer by reducing the expression of ribonucleotide reductase subunit-M2 (RRM2)." in: Journal of experimental & clinical cancer research : CR, Vol. 36, Issue 1, pp. 107, (2018) (PubMed).
: "E2F1 interactions with hHR23A inhibit its degradation and promote DNA repair." in: Oncotarget, Vol. 7, Issue 18, pp. 26275-92, (2018) (PubMed).
: "Dependence of p53-deficient cells on the DHX9 DExH-box helicase." in: Oncotarget, Vol. 8, Issue 19, pp. 30908-30921, (2017) (PubMed).
: "Cell-specific Kaiso (ZBTB33) Regulation of Cell Cycle through Cyclin D1 and Cyclin E1." in: The Journal of biological chemistry, Vol. 291, Issue 47, pp. 24538-24550, (2017) (PubMed).
: "Primate-specific miR-603 is implicated in the risk and pathogenesis of Alzheimer's disease." in: Aging, Vol. 8, Issue 2, pp. 272-90, (2016) (PubMed).
: "GCN5 Potentiates Glioma Proliferation and Invasion via STAT3 and AKT Signaling Pathways." in: International journal of molecular sciences, Vol. 16, Issue 9, pp. 21897-910, (2016) (PubMed).
Synonyme und alternative Namen zu E2F1
E2F transcription factor 1 (E2f1), E2F transcription factor 1 (E2F1), E2F transcription factor 1 L homeolog (e2f1.L), ATE2FB, CG6376, dE2F, dE2f, dE2F1, dE2f1, de2f1, def21, DmE2F-1, Dmel\\CG6376, Dp, drosE2F1, DRTF1/E2F, E(Sev-CycE)3A, E(var)3-93E, E(var)3-95E, E(var)93E, E2F, e2f, E2F-1, E2F1, E2f1, e2f1, E2FB, E2FB TRANSCRIPTION FACTOR, E2F TRANSCRIPTION FACTOR-1 E2F1, E2F transcription factor 1, Evar(3)164, l(3)07172, l(3)j3B1, l(3)j3C2, l(3)rM729, mKIAA4009, RBAP1, RBBP3, RBP3, xE2FBezeichner auf Proteinebene für E2F1
- CG6376-PA
- CG6376-PB
- CG6376-PC
- CG6376-PD
- E2-promoter binding factor
- E2f-PA
- E2f-PB
- E2f-PC
- E2f-PD
- PBR3
- PRB-binding protein E2F-1
- RBAP-1
- RBBP-3
- retinoblastoma-associated protein 1
- retinoblastoma-binding protein 3
- transcription factor E2F1
- E2F-1 transcription factor
- E2F-1
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