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E2F2 Produkte

(E2F Transcription Factor 2 (E2F2))

Kategorien

The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F1 and E2F3, have an additional cyclin binding domain. This protein binds specifically to retinoblastoma protein pRB in a cell-cycle dependent manner, and it exhibits overall 46% amino acid identity to E2F1. [provided by RefSeq, Jul 2008].

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Ausgewählte E2F2 Kategorien

E2F2 Antikörper

High quality antibodies with extensive validation data.

E2F2 ELISA Kits

Reliable ELISA kits for a wide range of species.

E2F2 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene E2F2 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC
Validierungen
  • (4)
Kat. Nr. ABIN7172517
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, PLA
Validierungen
  • (3)
Kat. Nr. ABIN515125
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human, Mouse
Applikation WB
Validierungen
  • (2)
Kat. Nr. ABIN654438
Menge 400 μL
Datenblatt Datenblatt

Empfohlene E2F2 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6955490
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN5653769
Menge 96 tests
Datenblatt Datenblatt

Empfohlene E2F2 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1352231
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1352233
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7505314
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren E2F2 Produkten

Liu, Zhang, Lan, Wang, Mou, Shao, Liu, Yang, Lin, Lin, Ji: "GCN5 Potentiates Glioma Proliferation and Invasion via STAT3 and AKT Signaling Pathways." in: International journal of molecular sciences, Vol. 16, Issue 9, pp. 21897-910, (2016) (PubMed).

Jung, Hsiung, Pestal, Procyk, Raulet: "RAE-1 ligands for the NKG2D receptor are regulated by E2F transcription factors, which control cell cycle entry." in: The Journal of experimental medicine, Vol. 209, Issue 13, pp. 2409-22, (2012) (PubMed).

Iwata, Maruyama, Akagi, Hashikawa, Kanazawa, Tsuji, Nukina: "Alpha-synuclein degradation by serine protease neurosin: implication for pathogenesis of synucleinopathies." in: Human molecular genetics, Vol. 12, Issue 20, pp. 2625-35, (2003) (PubMed).

Trimarchi, Fairchild, Verona, Moberg, Andon, Lees: "E2F-6, a member of the E2F family that can behave as a transcriptional repressor." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 95, Issue 6, pp. 2850-5, (1998) (PubMed).

Magae, Wu, Illenye, Harlow, Heintz: "Nuclear localization of DP and E2F transcription factors by heterodimeric partners and retinoblastoma protein family members." in: Journal of cell science, Vol. 109 ( Pt 7), Issue 25, pp. 1717-26, (1997) (PubMed).

Sladek: "E2F transcription factor action, regulation and possible role in human cancer." in: Cell proliferation, Vol. 30, Issue 3-4, pp. 97-105, (1997) (PubMed).

Lukas, Petersen, Holm, Bartek, Helin: "Deregulated expression of E2F family members induces S-phase entry and overcomes p16INK4A-mediated growth suppression." in: Molecular and cellular biology, Vol. 16, Issue 3, pp. 1047-57, (1996) (PubMed).

Nevins: "E2F: a link between the Rb tumor suppressor protein and viral oncoproteins." in: Science (New York, N.Y.), Vol. 258, Issue 5081, pp. 424-9, (1992) (PubMed).

Synonyme und alternative Namen zu E2F2

E2F transcription factor 2 (E2F2), E2F transcription factor 2 (E2f2), si:ch211-160f23.5 (si:ch211-160f23.5), 9230110J10, CG1071, dE2F-2, dE2F2, dE2f2, de2f2, Dmel\\CG1071, E2F, E2F-2, E2F2, e2f2, E130207A07, fb40b03, wu:fb40b03

Bezeichner auf Proteinebene für E2F2

  • transcription factor E2F2
  • CG1071-PA
  • E2f2-PA
  • E2F-2
  • LOW QUALITY PROTEIN: transcription factor E2F2
  • E2F transcription factor 2
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