EBP Produkte
(Emopamil Binding Protein (Sterol Isomerase) (EBP))
Kategorien
The protein encoded by this gene is an integral membrane protein of the endoplasmic reticulum. It is a high affinity binding protein for the antiischemic phenylalkylamine Ca2+ antagonist [3H]emopamil and the photoaffinity label [3H]azidopamil. It is similar to sigma receptors and may be a member of a superfamily of high affinity drug-binding proteins in the endoplasmic reticulum of different tissues. This protein shares structural features with bacterial and eukaryontic drug transporting proteins. It has four putative transmembrane segments and contains two conserved glutamate residues which may be involved in the transport of cationic amphiphilics. Another prominent feature of this protein is its high content of aromatic amino acid residues (>23%) in its transmembrane segments. These aromatic amino acid residues have been suggested to be involved in the drug transport by the P-glycoprotein. Mutations in this gene cause Chondrodysplasia punctata 2 (CDPX2\; also known as Conradi-Hunermann syndrome). [provided by RefSeq, Jul 2008].
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Ausgewählte EBP Kategorien
EBP Antikörper
High quality antibodies with extensive validation data.
EBP ELISA Kits
Reliable ELISA kits for a wide range of species.
EBP Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene EBP Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
ELISA, WB, IHC, IF
Validierungen
- (4)
Kat. Nr.
ABIN7142288
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB
Validierungen
- (3)
- (2)
Kat. Nr.
ABIN1881278
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, FACS, IHC (p)
Validierungen
- (3)
Kat. Nr.
ABIN652952
Menge
400 μL
Datenblatt
Datenblatt
Empfohlene EBP ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Validierungen
Kat. Nr.
ABIN1118973
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Validierungen
Kat. Nr.
ABIN1118974
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Validierungen
Kat. Nr.
ABIN1118975
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene EBP Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (1)
Kat. Nr.
ABIN2712409
Menge
20 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren EBP Produkten
: "Two novel EBP mutations in Conradi-Hünermann-Happle syndrome." in: European journal of dermatology : EJD, Vol. 18, Issue 4, pp. 391-3, (2008) (PubMed).: "Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations." in: Journal of lipid research, Vol. 49, Issue 12, pp. 2582-9, (2008) (PubMed).
: "Novel EBP gene mutations in Conradi-Hünermann-Happle syndrome." in: The British journal of dermatology, Vol. 157, Issue 6, pp. 1225-9, (2007) (PubMed).
Synonyme und alternative Namen zu EBP
emopamil binding protein (sterol isomerase) (Ebp), emopamil binding protein (sterol isomerase) L homeolog (ebp.L), emopamil binding protein (sterol isomerase) (ebp), emopamil binding protein (sterol isomerase) (EBP), phenylalkylamine Ca2+ antagonist (emopamil) binding protein (Ebp), AI255399, cdpx2, CDPX2, cho2, CHO2, cpx, CPX, cpxd, CPXD, mSI, Pabp, Td, zgc:91895Bezeichner auf Proteinebene für EBP
- 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase
- D8-D7 sterol isomerase
- emopamil-binding protein
- cholestenol Delta-isomerase
- phenylalkylamine binding protein
- delta(8)-Delta(7) sterol isomerase
- emopamil binding protein (sterol isomerase)
- 3-beta-hydroxysteroid-delta-8,delta-7-isomerase
- Chondrodysplasia punctata-2, X-linked dominant (Happle syndrome)
- emopamil-binding protein (sterol isomerase)
- sterol 8-isomerase
- phenylalkylamine Ca2+ antagonist (emopamil) binding protein
- tattered
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