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EGFR Produkte

(Epidermal Growth Factor Receptor (EGFR))

Kategorien

The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Jul 2010].

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Ausgewählte EGFR Kategorien

EGFR Antikörper

High quality antibodies with extensive validation data.

EGFR ELISA Kits

Reliable ELISA kits for a wide range of species.

EGFR Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene EGFR Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA, IP
Validierungen
  • (3)
  • (2)
  • (1)
Kat. Nr. ABIN98862
Menge 250 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, IP, ICC
Validierungen
  • (6)
Kat. Nr. ABIN7426025
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC (p)
Validierungen
  • (6)
Kat. Nr. ABIN1882237
Menge 400 μL
Datenblatt Datenblatt

Empfohlene EGFR ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN837930
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Semi-Quantitative Cell ELISA
Validierungen
  • (4)
  • (5)
Kat. Nr. ABIN1981827
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Analytical Method Semi-Quantitative Cell ELISA
Validierungen
  • (4)
  • (5)
Kat. Nr. ABIN1981825
Menge 96 tests
Datenblatt Datenblatt

Empfohlene EGFR Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (4)
Kat. Nr. ABIN7274526
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (4)
Kat. Nr. ABIN7274527
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (3)
Kat. Nr. ABIN7274524
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren EGFR Produkten

Haueis, Stech, Kubick: "A Cell-free Expression Pipeline for the Generation and Functional Characterization of Nanobodies." in: Frontiers in bioengineering and biotechnology, Vol. 10, pp. 896763, (2022) (PubMed).

Lanzerstorfer, Müller, Gordiyenko, Weghuber, Niemeyer: "Highly Modular Protein Micropatterning Sheds Light on the Role of Clathrin-Mediated Endocytosis for the Quantitative Analysis of Protein-Protein Interactions in Live Cells." in: Biomolecules, Vol. 10, Issue 4, (2021) (PubMed).

Saveri, De Luca, Nisi, Pisciotta, Romano, Piscosquito, Reilly, Polke, Cavallaro, Fabrizi, Fossa, Cichero, Lombardi, Lauria, Magri, Taroni, Pareyson, Bucci: "Charcot-Marie-Tooth Type 2B: A New Phenotype Associated with a Novel RAB7A Mutation and Inhibited EGFR Degradation." in: Cells, Vol. 9, Issue 4, (2020) (PubMed).

Larios, Mercier, Roux, Gruenberg: "ALIX- and ESCRT-III-dependent sorting of tetraspanins to exosomes." in: The Journal of cell biology, Vol. 219, Issue 3, (2020) (PubMed).

Murakami, Matsumoto, Kanamori: "Constructive approach for synthesis of a functional IgG using a reconstituted cell-free protein synthesis system." in: Scientific reports, Vol. 9, Issue 1, pp. 671, (2020) (PubMed).

El-Sharief, Ammar, Belal, El-Sharief, Mohamed, Mehany, Elhag Ali, Ragab: "Design, synthesis, molecular docking and biological activity evaluation of some novel indole derivatives as potent anticancer active agents and apoptosis inducers." in: Bioorganic chemistry, Vol. 85, pp. 399-412, (2020) (PubMed).

Al-Harbi, El-Sharief, Abbas: "Synthesis and anticancer activity of bis-benzo[d][1,3]dioxol-5-yl thiourea derivatives with molecular docking study." in: Bioorganic chemistry, Vol. 90, pp. 103088, (2020) (PubMed).

Tang, Zheng, Melo, Mabardi, Castaño, Xie, Li, Kudchodkar, Wong, Jeng, Maus, Irvine: "Enhancing T cell therapy through TCR-signaling-responsive nanoparticle drug delivery." in: Nature biotechnology, Vol. 36, Issue 8, pp. 707-716, (2019) (PubMed).

Mortensen, Skovsgaard, Okholm, Scavenius, Dupont, Rosen, Enghild, Kjems, Gothelf: "Small-Molecule Probes for Affinity-Guided Introduction of Biocompatible Handles on Metal-Binding Proteins." in: Bioconjugate chemistry, Vol. 29, Issue 9, pp. 3016-3025, (2019) (PubMed).

Hu, Wang, Jin, Liu, Cui, Sun, Li, Li, Wang, Zhen, Miao, Li: "An EGFR-targeting antibody-drug conjugate LR004-VC-MMAE: potential in esophageal squamous cell carcinoma and other malignancies." in: Molecular oncology, Vol. 13, Issue 2, pp. 246-263, (2019) (PubMed).

Synonyme und alternative Namen zu EGFR

epidermal growth factor receptor (EGFR), Epidermal growth factor receptor (Egfr), epidermal growth factor receptor a (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) (egfra), epidermal growth factor receptor (egfr1), epidermal growth factor receptor (LOC5564544), epidermal growth factor receptor (Egfr), 9030024J15Rik, AI552599, C-erb, c-erbB, CG10079, D-Egf, d-egf-r, D-EGFR, DEGFR, DEgfr, Degfr, dEGFR, dEgfr, dEGFR1, DER, Der, der, DER/EGFR, DER/faint little ball, DER/top, DER/torpedo, DER1, DER flb, Dmel\\CG10079, DmHD-33, EFG-R, Egf, EGF-R, Egf-r, EGFR, EGFr, EGfr, EgfR, egfr, egfr1, EGFR12, EGFR15, EK2-6, El, Elp, Elp-1, Elp-B1, Elp-B1RB1, ERBB, Erbb, ErbB-1, ERBB1, Erbb2, Errb1, Errp, flb, HD-33, HER1, l(2)05351, l(2)09261, l(2)57DEFa, l(2)57Ea, l(2)57EFa, mENA, mor1, PIG61, TOP, top, top/DER, top/flb, Torpedo/DER, Torpedo/Egfr, torpedo/Egfr, torpedo/egfr, wa-2, wa2, Wa5

Bezeichner auf Proteinebene für EGFR

  • CG10079-PA
  • CG10079-PB
  • DER-Ellipse
  • EGF-receptor
  • EGFR
  • Egf receptor
  • Egfr-PA
  • Egfr-PB
  • drosophila epidermal growth factor receptor homologue
  • ellipse
  • ellipse torpedo
  • epidermal growth factor receptor
  • faint little ball
  • morphological defects 1
  • torpedo
  • torpedo/DER
  • erbb1a
  • avian erythroblastic leukemia viral (v-erb-b) oncogene homolog
  • cell growth inhibiting protein 40
  • cell proliferation-inducing protein 61
  • proto-oncogene c-ErbB-1
  • receptor tyrosine-protein kinase erbB-1
  • EGFR-related peptide
  • Epidermal growth factor receptor formerly avian erythroblastic leukemia viral (v-erbB) oncogene homolog (Erbb1)
  • avian erythroblastic leukemia viral (v-erbB) oncogene homolog
  • epidermal growth factor receptor, formerly avian erythroblastic leukemia viral (v-erbB) oncogene homolog (Erbb1)
  • waved 2
  • CER
  • epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)
  • egf receptor
  • receptor tyrosine kinase ErbB1
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