EGLN1 Produkte
(Egl-9 Family Hypoxia Inducible Factor 1 (EGLN1))
Kategorien
The protein encoded by this gene catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. HIF is a transcriptional complex that plays a central role in mammalian oxygen homeostasis. This protein functions as a cellular oxygen sensor, and under normal oxygen concentration, modification by prolyl hydroxylation is a key regulatory event that targets HIF subunits for proteasomal destruction via the von Hippel-Lindau ubiquitylation complex. Mutations in this gene are associated with erythrocytosis familial type 3 (ECYT3). [provided by RefSeq, Nov 2009].
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Ausgewählte EGLN1 Kategorien
EGLN1 Antikörper
High quality antibodies with extensive validation data.
EGLN1 ELISA Kits
Reliable ELISA kits for a wide range of species.
EGLN1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene EGLN1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IF
Validierungen
- (6)
Kat. Nr.
ABIN7266909
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC
Validierungen
- (2)
Kat. Nr.
ABIN7151443
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validierungen
- (2)
Kat. Nr.
ABIN702640
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene EGLN1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6955511
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6955510
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN5653787
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene EGLN1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1352445
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1352443
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7409743
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren EGLN1 Produkten
: "Loss of Phd2 cooperates with BRAFV600E to drive melanomagenesis. ..." in: Nature communications, Vol. 9, Issue 1, pp. 5426, (2019) (PubMed).: "Inducing cancer indolence by targeting mitochondrial Complex I is potentiated by blocking macrophage-mediated adaptive responses. ..." in: Nature communications, Vol. 10, Issue 1, pp. 903, (2019) (PubMed).
: "Metallothionein 3 Controls the Phenotype and Metabolic Programming of Alternatively Activated Macrophages." in: Cell reports, Vol. 27, Issue 13, pp. 3873-3886.e7, (2019) (PubMed).
: "A RASSF1A-HIF1α loop drives Warburg effect in cancer and pulmonary hypertension." in: Nature communications, Vol. 10, Issue 1, pp. 2130, (2019) (PubMed).
: "Systemic silencing of PHD2 causes reversible immune regulatory dysfunction. ..." in: The Journal of clinical investigation, Vol. 130, pp. 3640-3656, (2019) (PubMed).
: "The Factor Inhibiting HIF Asparaginyl Hydroxylase Regulates Oxidative Metabolism and Accelerates Metabolic Adaptation to Hypoxia." in: Cell metabolism, Vol. 27, Issue 4, pp. 898-913.e7, (2018) (PubMed).
: "Intermittent hypoxia induces beneficial cardiovascular remodeling in left ventricular function of type 1 diabetic rat." in: Anatolian journal of cardiology, Vol. 19, Issue 4, pp. 259-266, (2018) (PubMed).
: "Redox regulation of EGFR steers migration of hypoxic mammary cells towards oxygen." in: Nature communications, Vol. 9, Issue 1, pp. 4545, (2018) (PubMed).
: "The vacuolar-ATPase complex and assembly factors, TMEM199 and CCDC115, control HIF1α prolyl hydroxylation by regulating cellular iron levels." in: eLife, Vol. 6, (2017) (PubMed).
: "Ablation of endothelial prolyl hydroxylase domain protein-2 promotes renal vascular remodelling and fibrosis in mice." in: Journal of cellular and molecular medicine, (2017) (PubMed).
Synonyme und alternative Namen zu EGLN1
egl nine homolog 1 (C. elegans) (EGLN1), egl-9 family hypoxia inducible factor 1 (EGLN1), egl-9 family hypoxia-inducible factor 1 S homeolog (egln1.S), egl-9 family hypoxia-inducible factor 1b (egln1b), egl-9 family hypoxia-inducible factor 1 (Egln1), AI503754, C1orf12, ECYT3, EGLN1, egln2, Hif-p4h-2, HIF-PH2, HIFPH2, HPH-2, HPH2, ORF13, PHD-2, phd2, Phd2, PHD2, SM-20, SM20, zgc:92314, ZMYND6Bezeichner auf Proteinebene für EGLN1
- egl nine homolog 1 (C. elegans)
- egl nine homolog 1
- egl nine homolog 1-like
- egl nine homolog 2
- Hif-p4h-2
- HIF-prolyl hydroxylase 2
- hypoxia-inducible factor prolyl hydroxylase 2
- prolyl hydroxylase domain-containing protein 2
- HIF prolyl hydroxylase 2
- egl nine-like protein 1
- zinc finger MYND domain-containing protein 6
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