EIF2S1 Produkte
(Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1))
Kategorien
The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2\; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3\; MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987 [PubMed 2948954]).[supplied by OMIM, Feb 2010].
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Ausgewählte EIF2S1 Kategorien
EIF2S1 Antikörper
High quality antibodies with extensive validation data.
EIF2S1 ELISA Kits
Reliable ELISA kits for a wide range of species.
EIF2S1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene EIF2S1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IF, RNAi
Validierungen
- (1)
- (7)
Kat. Nr.
ABIN560711
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, IHC, ELISA, IF, ICC
Validierungen
- (2)
- (13)
Kat. Nr.
ABIN6255389
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Dog, Human, Monkey, Rat
Applikation
WB, IHC, IHC (p)
Validierungen
- (7)
Kat. Nr.
ABIN1497972
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene EIF2S1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6966606
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene EIF2S1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1352542
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN667786
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7420222
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren EIF2S1 Produkten
: "Betulinic acid chemosensitizes breast cancer by triggering ER stress-mediated apoptosis by directly targeting GRP78." in: Cell death & disease, Vol. 9, Issue 6, pp. 636, (2018) (PubMed).: "EndophilinA2 protects against angiotensin II-induced cardiac hypertrophy by inhibiting angiotensin II type 1 receptor trafficking in neonatal rat cardiomyocytes." in: Journal of cellular biochemistry, (2018) (PubMed).
: "Combination of the novel histone deacetylase inhibitor YCW1 and radiation induces autophagic cell death through the downregulation of BNIP3 in triple-negative breast cancer cells in vitro and in an ..." in: Molecular cancer, Vol. 15, Issue 1, pp. 46, (2017) (PubMed).
: "Midazolam regulated caspase pathway, endoplasmic reticulum stress, autophagy, and cell cycle to induce apoptosis in MA-10 mouse Leydig tumor cells." in: OncoTargets and therapy, Vol. 9, pp. 2519-33, (2016) (PubMed).
: "The spliceosome is a therapeutic vulnerability in MYC-driven cancer. ..." in: Nature, Vol. 525, Issue 7569, pp. 384-8, (2015) (PubMed).
: "IGF2BP1 enhances HCV IRES-mediated translation initiation via the 3'UTR." in: RNA (New York, N.Y.), Vol. 15, Issue 8, pp. 1528-42, (2009) (PubMed).
: "Hypoxia inhibits protein synthesis through a 4E-BP1 and elongation factor 2 kinase pathway controlled by mTOR and uncoupled in breast cancer cells." in: Molecular and cellular biology, Vol. 26, Issue 10, pp. 3955-65, (2006) (PubMed).
: "Identification of a hydrogen peroxide-induced PP1-JNK1-Sp1 signaling pathway for gene regulation." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 291, Issue 5, pp. L983-92, (2006) (PubMed).
: "Rapamycin-induced translational derepression of GCN4 mRNA involves a novel mechanism for activation of the eIF2 alpha kinase GCN2." in: The Journal of biological chemistry, Vol. 278, Issue 23, pp. 20457-60, (2003) (PubMed).
: "Identification and characterization of a novel transcription factor participating in the expression of eukaryotic initiation factor 2 alpha." in: The Journal of biological chemistry, Vol. 264, Issue 34, pp. 20372-84, (1990) (PubMed).
Synonyme und alternative Namen zu EIF2S1
eukaryotic translation initiation factor 2 subunit alpha (EIF2S1), eukaryotic translation initiation factor 2, subunit 1 alpha a (eif2s1a), eukaryotic translation initiation factor 2 subunit alpha (Eif2s1), eukaryotic translation initiation factor 2, subunit 1 alpha (Eif2s1), eukaryotic translation initiation factor 2 subunit alpha (eif2s1), eukaryotic translation initiation factor 2 alpha subunit (LOC693063), eukaryotic translation initiation factor 2 alpha subunit (CNI00230), eukaryotic translation initiation factor 2 alpha subunit (THAPSDRAFT_105), Eukaryotic translation initiation factor 2 subunit 1 (if2a), eukaryotic translation initiation factor 2 subunit alpha L homeolog (eif2s1.L), eukaryotic translation Initiation Factor 2alpha (eIF-2alpha), 35kDa, 0910001O23Rik, 2410026C18Rik, CG9946, deIF2alpha, Dmel\\CG9946, EIF-2, eIF-2, eIF-2 a, eIF-2 alpha, EIF-2A, EIF-2alpha, eiF-2alpha, EIF2, eIF2 alpha, eIF2-alpha, EIF2A, Eif2a, eif2a, eIF2a, eIF2alpha, Eif2alpha, Eif2s1, eif2s1l, elF2alpha, fb36a08, IF2A_DROME, l(1)14Cf, l(1)19-153, M(1)8e3-10, M(1)14C, M(1)19-153, wu:fb36a08, zgc:56510Bezeichner auf Proteinebene für EIF2S1
- eIF-2-alpha
- eukaryotic translation initiation factor 2 subunit 1
- eukaryotic translation initiation factor 2 subunit alpha
- eukaryotic translation initiation factor 2, subunit 1 alpha
- eukaryotic translation initiation factor 2, subunit 1 alpha, like
- EIF-2A
- EIF-2alpha
- eIF-2A
- eIF-2alpha
- eukaryotic translation initiation factor 2A
- eukaryotic translation initiation factor 2 alpha subunit
- Eukaryotic translation initiation factor 2 subunit 1
- eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
- eukaryotic translation initiation factor 2, subunit 1 (alpha )
- CG9946-PA
- eIF-2alpha-PA
- eukaryotic initiation factor 2alpha
- eukaryotic translation initiation factor 2
- eukaryotic translation initiation factor 2alpha
- minute (1) 14C
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