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ENPP2 Produkte

(Ectonucleotide Pyrophosphatase/phosphodiesterase 2 (ENPP2))
The protein encoded by this gene functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This gene product stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The gene product is secreted and further processed to make the biologically active form. Several alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2008].

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Ausgewählte ENPP2 Kategorien

ENPP2 Antikörper

High quality antibodies with extensive validation data.

ENPP2 ELISA Kits

Reliable ELISA kits for a wide range of species.

ENPP2 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene ENPP2 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, FACS, ICC, IF
Validierungen
  • (1)
  • (6)
Kat. Nr. ABIN2856278
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, FACS
Validierungen
  • (5)
Kat. Nr. ABIN650746
Menge 200 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, IP, ICC
Validierungen
  • (4)
Kat. Nr. ABIN7427858
Menge 100 μL
Datenblatt Datenblatt

Empfohlene ENPP2 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6955502
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6955503
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6955504
Menge 96 tests
Datenblatt Datenblatt

Empfohlene ENPP2 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (2)
Kat. Nr. ABIN7274534
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Mouse
Source HEK-293 Cells
Validierungen
  • (2)
Kat. Nr. ABIN7274543
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7122741
Menge 50 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren ENPP2 Produkten

Tsukahara, Haniu, Uemura, Matsuda: "Porcine liver decomposition product-derived lysophospholipids promote microglial activation in vitro." in: Scientific reports, Vol. 10, Issue 1, pp. 3748, (2020) (PubMed).

Miao, Zhao, Han, Ma, Deng, Yang, Lü, Shao, Kong, Wang, Xu, Wang, Feng: "NSun2 regulates aneurysm formation by promoting autotaxin expression and T cell recruitment." in: Cellular and molecular life sciences : CMLS, (2020) (PubMed).

Lee, Fiene, Li, Hanck, Brylev, Fedorov, Lecka, Haider, Pietzsch, Zimmermann, Sévigny, Kortz, Stephan, Müller: "Polyoxometalates--potent and selective ecto-nucleotidase inhibitors." in: Biochemical pharmacology, Vol. 93, Issue 2, pp. 171-81, (2015) (PubMed).

Koike, Keino-Masu, Ohto, Masu: "The N-terminal hydrophobic sequence of autotaxin (ENPP2) functions as a signal peptide." in: Genes to cells : devoted to molecular & cellular mechanisms, Vol. 11, Issue 2, pp. 133-42, (2006) (PubMed).

Stefan, Jansen, Bollen: "NPP-type ectophosphodiesterases: unity in diversity." in: Trends in biochemical sciences, Vol. 30, Issue 10, pp. 542-50, (2005) (PubMed).

Sato, Malchinkhuu, Muraki, Ishikawa, Hayashi, Tosaka, Mochiduki, Inoue, Tomura, Mogi, Nochi, Tamoto, Okajima: "Identification of autotaxin as a neurite retraction-inducing factor of PC12 cells in cerebrospinal fluid and its possible sources." in: Journal of neurochemistry, Vol. 92, Issue 4, pp. 904-14, (2005) (PubMed).

Tanaka, Kishi, Takanezawa, Kakehi, Aoki, Arai: "Prostatic acid phosphatase degrades lysophosphatidic acid in seminal plasma." in: FEBS letters, Vol. 571, Issue 1-3, pp. 197-204, (2004) (PubMed).

Strausberg, Feingold, Grouse, Derge, Klausner, Collins, Wagner, Shenmen, Schuler, Altschul, Zeeberg, Buetow, Schaefer, Bhat, Hopkins, Jordan, Moore, Max, Wang, Hsieh, Diatchenko, Marusina, Farmer et al.: "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. ..." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 26, pp. 16899-903, (2002) (PubMed).

Synonyme und alternative Namen zu ENPP2

ectonucleotide pyrophosphatase/phosphodiesterase 2 (ENPP2), ectonucleotide pyrophosphatase/phosphodiesterase 2 (Enpp2), ectonucleotide pyrophosphatase/phosphodiesterase 2 (enpp2), ectonucleotide pyrophosphatase/phosphodiesterase 2 L homeolog (enpp2.L), ectonucleotide pyrophosphatase/phosphodiesterase 2 S homeolog (enpp2.S), ATX, atx, ATX-X, AUTOTAXIN, autotaxin, enpp2, enpp2a, enpp2b, LysoPLD, MGC132047, NPP2, Npps2, PD-IALPHA, PD-Ialpha, PDNP2, Pdnp2, zgc:63550

Bezeichner auf Proteinebene für ENPP2

  • E-NPP 2
  • autotaxin-t
  • ectonucleotide pyrophosphatase/phosphodiesterase family member 2
  • extracellular lysophospholipase D
  • phosphodiesterase I/nucleotide pyrophosphatase 2
  • plasma lysophospholipase D
  • autotaxin
  • lysoPLD
  • phosphodiesterase I/nucleotide pyrophosphatase 2 (autotaxin)
  • ectonucleotide pyrophosphatase/phosphodiesterase 2 (autotaxin)
  • ectonucleotide pyrophosphatase/phosphodiesterase 2
  • ectonucleotide pyrophosphatase/phosphodiesterase family member 2 isoform 2 preproprotein
  • ectonucleotide pyrophosphatase/phosphodiesterase 2 S homeolog
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