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EPM2A Produkte

(Epilepsy, Progressive Myoclonus Type 2A, Lafora Disease (Laforin) (EPM2A))

Kategorien

This gene encodes a dual-specificity phosphatase that associates with polyribosomes. The encoded protein may be involved in the regulation of glycogen metabolism. Mutations in this gene have been associated with myoclonic epilepsy of Lafora. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008].

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Ausgewählte EPM2A Kategorien

EPM2A Antikörper

High quality antibodies with extensive validation data.

EPM2A ELISA Kits

Reliable ELISA kits for a wide range of species.

EPM2A Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene EPM2A Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA
Validierungen
  • (8)
  • (4)
Kat. Nr. ABIN563505
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IF, IHC (p), ICC
Validierungen
  • (4)
Kat. Nr. ABIN2855883
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC, IF
Validierungen
  • (3)
Kat. Nr. ABIN7157846
Menge 100 μg
Datenblatt Datenblatt

Empfohlene EPM2A ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method
Validierungen
Kat. Nr. ABIN1139969
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method
Validierungen
Kat. Nr. ABIN1139970
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method
Validierungen
Kat. Nr. ABIN1139971
Menge 96 tests
Datenblatt Datenblatt

Empfohlene EPM2A Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1352959
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1352957
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr. ABIN3092377
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren EPM2A Produkten

Irimia, Tagliabracci, Meyer, Segvich, DePaoli-Roach, Roach: "Muscle glycogen remodeling and glycogen phosphate metabolism following exhaustive exercise of wild type and laforin knockout mice." in: The Journal of biological chemistry, (2015) (PubMed).

Zhu, Zhang, Kelly, Cheng: "The carbohydrate-binding domain of overexpressed STBD1 is important for its stability and protein-protein interactions." in: Bioscience reports, Vol. 34, Issue 4, (2014) (PubMed).

Sherwood, Johnson, Delgado-Escueta, Gentry: "A bioassay for Lafora disease and laforin glucan phosphatase activity." in: Clinical biochemistry, Vol. 46, Issue 18, pp. 1869-76, (2013) (PubMed).

DePaoli-Roach, Segvich, Meyer, Rahimi, Worby, Gentry, Roach: "Laforin and malin knockout mice have normal glucose disposal and insulin sensitivity." in: Human molecular genetics, Vol. 21, Issue 7, pp. 1604-10, (2012) (PubMed).

Tiberia, Turnbull, Wang, Ruggieri, Zhao, Pencea, Israelian, Wang, Ackerley, Wang, Liu, Minassian: "Increased laforin and laforin binding to glycogen underlie Lafora body formation in malin-deficient Lafora disease." in: The Journal of biological chemistry, Vol. 287, Issue 30, pp. 25650-9, (2012) (PubMed).

Turnbull, Girard, Lohi, Chan, Wang, Tiberia, Omer, Ahmed, Bennett, Chakrabarty, Tyagi, Liu, Pencea, Zhao, Scherer, Ackerley, Minassian: "Early-onset Lafora body disease." in: Brain : a journal of neurology, Vol. 135, Issue Pt 9, pp. 2684-98, (2012) (PubMed).

Turnbull, Wang, Girard, Ruggieri, Wang, Draginov, Kameka, Pencea, Zhao, Ackerley, Minassian: "Glycogen hyperphosphorylation underlies lafora body formation." in: Annals of neurology, Vol. 68, Issue 6, pp. 925-33, (2011) (PubMed).

Tagliabracci, Turnbull, Wang, Girard, Zhao, Skurat, Delgado-Escueta, Minassian, Depaoli-Roach, Roach: "Laforin is a glycogen phosphatase, deficiency of which leads to elevated phosphorylation of glycogen in vivo." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 49, pp. 19262-6, (2007) (PubMed).

Mittal, Dubey, Yamakawa, Ganesh: "Lafora disease proteins malin and laforin are recruited to aggresomes in response to proteasomal impairment." in: Human molecular genetics, Vol. 16, Issue 7, pp. 753-62, (2007) (PubMed).

Wang, Parker, Skurat, Raben, DePaoli-Roach, Roach: "Relationship between glycogen accumulation and the laforin dual specificity phosphatase." in: Biochemical and biophysical research communications, Vol. 350, Issue 3, pp. 588-92, (2006) (PubMed).

Synonyme und alternative Namen zu EPM2A

EPM2A, laforin glucan phosphatase (EPM2A), epilepsy, progressive myoclonic epilepsy, type 2 gene alpha (Epm2a), EPM2A, laforin glucan phosphatase (Epm2a), EPM2, laforin, MELF, Tg(TcraK,TcrbK)TG-BFlv, TG-B

Bezeichner auf Proteinebene für EPM2A

  • laforin
  • LAFPTPase
  • lafora PTPase
  • epilepsy, progressive myoclonic epilepsy, type 2 gene alpha
  • epilepsy, progressive myoclonus type 2, Lafora disease (laforin)
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