ERCC2 Produkte
(Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation Group 2 (ERCC2))
Kategorien
The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008].
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Ausgewählte ERCC2 Kategorien
ERCC2 Antikörper
High quality antibodies with extensive validation data.
ERCC2 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene ERCC2 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, IF, ICC, IHC (p)
Validierungen
- (4)
Kat. Nr.
ABIN2856090
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC
Validierungen
- (3)
Kat. Nr.
ABIN7171956
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IF
Validierungen
- (3)
Kat. Nr.
ABIN515384
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene ERCC2 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6960582
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN5608594
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN5660069
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene ERCC2 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN1353031
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1353033
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7418473
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren ERCC2 Produkten
: "XPD localizes in mitochondria and protects the mitochondrial genome from oxidative DNA damage." in: Nucleic acids research, Vol. 43, Issue 11, pp. 5476-88, (2015) (PubMed).: "Cadmium inhibits non-homologous end-joining and over-activates the MRE11-dependent repair pathway." in: Mutation research, Vol. 654, Issue 1, pp. 13-21, (2008) (PubMed).
: "Mutations in the XPD helicase gene result in XP and TTD phenotypes, preventing interaction between XPD and the p44 subunit of TFIIH." in: Nature genetics, Vol. 20, Issue 2, pp. 184-8, (1998) (PubMed).
Synonyme und alternative Namen zu ERCC2
ERCC excision repair 2, TFIIH core complex helicase subunit (ERCC2), excision repair cross-complementing rodent repair deficiency, complementation group 2 (Ercc2), ERCC excision repair 2, TFIIH core complex helicase subunit (Ercc2), excision repair cross-complementation group 2 (ercc2), Xeroderma pigmentosum D (Xpd), AA407812, AU020867, AW240756, CG9433, COFS2, CXPD, DhR3, DhXPD, Dmel\\CG9433, DmXPD, EM9, Ercc-2, ERCC2, l(2)SH2 2137, l(2)SH2137, MGC89573, TTD, XPD, xpd, XPD/ERCC2, zgc:56365Bezeichner auf Proteinebene für ERCC2
- BTF2 p80
- CXPD
- DNA excision repair protein ERCC-2
- DNA repair protein complementing XP-D cells
- TFIIH 80 kDa subunit
- TFIIH basal transcription factor complex 80 kDa subunit
- TFIIH basal transcription factor complex helicase XPD subunit
- TFIIH basal transcription factor complex helicase subunit
- TFIIH p80
- basic transcription factor 2 80 kDa subunit
- xeroderma pigmentosum complementary group D
- xeroderma pigmentosum group D-complementing protein
- excision repair cross-complementing rodent repair deficiency, complementation group 2 (xeroderma pigmentosum D)
- excision repair cross-complementing rodent repair deficiency, complementation group 2 protein
- excision repair cross-complementing rodent repair deficiency, complementation group 2
- excision repair cross-complementing 2
- DNA-repair protein complementing XP-D cells
- excision repair cross-complementing rodent repair deficiency, complementation group 6-like group 2
- CG9433-PA
- CG9433-PB
- CG9433-PC
- Xpd-PA
- Xpd-PB
- Xpd-PC
- lethal (2) SH2137
- xeroderma pigmentosum D
- XPD
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