EWSR1 Produkte
(Ewing Sarcoma Breakpoint Region 1 (EWSR1))
Kategorien
This gene encodes a multifunctional protein that is involved in various cellular processes, including gene expression, cell signaling, and RNA processing and transport. The protein includes an N-terminal transcriptional activation domain and a C-terminal RNA-binding domain. Chromosomal translocations between this gene and various genes encoding transcription factors result in the production of chimeric proteins that are involved in tumorigenesis. These chimeric proteins usually consist of the N-terminal transcriptional activation domain of this protein fused to the C-terminal DNA-binding domain of the transcription factor protein. Mutations in this gene, specifically a t(11\;22)(q24\;q12) translocation, are known to cause Ewing sarcoma as well as neuroectodermal and various other tumors. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and 14. [provided by RefSeq, Jul 2009].
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Ausgewählte EWSR1 Kategorien
EWSR1 Antikörper
High quality antibodies with extensive validation data.
EWSR1 ELISA Kits
Reliable ELISA kits for a wide range of species.
EWSR1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene EWSR1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC
Validierungen
- (6)
Kat. Nr.
ABIN335135
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC (p)
Validierungen
- (4)
Kat. Nr.
ABIN560815
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
Applikation
WB, IHC
Validierungen
- (5)
Kat. Nr.
ABIN2779045
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene EWSR1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Validierungen
Kat. Nr.
ABIN1156238
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Validierungen
Kat. Nr.
ABIN1156239
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene EWSR1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1353206
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN2720598
Menge
20 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren EWSR1 Produkten
: "Liquid demixing of intrinsically disordered proteins is seeded by poly(ADP-ribose)." in: Nature communications, Vol. 6, pp. 8088, (2015) (PubMed).: "Accumulation of pre-let-7g and downregulation of mature let-7g with the depletion of EWS." in: Biochemical and biophysical research communications, Vol. 426, Issue 1, pp. 89-93, (2012) (PubMed).
: "Oncoprotein EWS-FLI1 activity is enhanced by RNA helicase A." in: Cancer research, Vol. 66, Issue 11, pp. 5574-81, (2006) (PubMed).
: "Oncogenic MITF dysregulation in clear cell sarcoma: defining the MiT family of human cancers." in: Cancer cell, Vol. 9, Issue 6, pp. 473-84, (2006) (PubMed).
Synonyme und alternative Namen zu EWSR1
EWS RNA binding protein 1 (EWSR1), Ewing sarcoma breakpoint region 1 (Ewsr1), EWS RNA-binding protein 1 (Ewsr1), EWS RNA-binding protein 1a (ewsr1a), EWS RNA binding protein 1 (ewsr1), EWS RNA binding protein 1 (Ewsr1), EWS RNA binding protein 1 L homeolog (ewsr1.L), EWS RNA-binding protein 1b (ewsr1b), AU018891, bK984G1.4, DKFZp459K1116, EWS, Ews, Ewsh, EWSR1, ewsr1, ewsr1.S, fb40b11, fc04c01, fusl, wu:fb40b11, wu:fb75g09, wu:fc04c01, zgc:55864Bezeichner auf Proteinebene für EWSR1
- Ewing sarcoma breakpoint region 1
- Ewings sarcoma EWS-Fli1 (type 1) oncogene
- RNA-binding protein EWS
- Ewing sarcoma homolog
- Ewing sarcoma RNA-binding protein
- EWS RNA binding protein 1 S homeolog
- uncharacterized protein LOC734969
- Ewing sarcoma breakpoint region 1b
- fusion, derived from t(12;16) malignant liposarcoma, like
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