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EXOS Antikörper (cleaved)

EXOS Reaktivität: Pseudomonas aeruginosa WB Wirt: Huhn Polyclonal unconjugated
Produktnummer ABIN93557
  • Target
    EXOS (ExoS Gene Product (EXOS))
    Bindungsspezifität
    cleaved
    Reaktivität
    Pseudomonas aeruginosa
    Wirt
    Huhn
    Klonalität
    Polyklonal
    Applikation
    Western Blotting (WB)
    Kreuzreaktivität (Details)
    Not reactive in: no confirmed exceptions from predicted reactivity known in the moment
    Homologie
    Pseudomonas aeruginosa only
    Produktmerkmale
    Expected / apparent Molecular Weight of the Antigene: 48 kDa
    Aufreinigung
    affinity purified
    Immunogen
    amino acids 366 to 453 of PA3841 of ADP-rbosylating enzyme - Exoenzyme S overexpressed in a GST fusion. Afterwards cleaved with a help of trombin and separated on a polyacrylamide gel. Gel piece has been used for immunizations.
    Isotyp
    IgY
  • Applikationshinweise
    1: 5000 (WB)
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS pH 8.0+ 0.02 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from liquid material adhering to the cap or sides of the tubes.
    Make aliquots to avoid repreated freeze-thaw cycles and working with a stock.
    Lagerung
    4 °C
    Informationen zur Lagerung
    store at 4°C, make aliquots to avoid working with a stock. Please, remember to spin tubes briefly prior to opening them to avoid any losses that might occur from liquid material adhering to the cap or sides of the tubes.
  • Shen, Tsay, Chia, Wu, Lee, Hu: "The Role of Type III Secretion System and Lens Material on the Adhesion of Pseudomonas aeruginosa to Contact Lenses." in: Investigative ophthalmology & visual science, (2012) (PubMed).

  • Target
    EXOS (ExoS Gene Product (EXOS))
    Andere Bezeichnung
    Exoenzyme S (ExoS)
    Hintergrund
    Exoenzyme S (ExoS) is a toxin directly translocated into eukaryotic cells by the type III secretory process of Pseudomonas aeruginosa. It is a bi-functional toxin and contain an N-terminal Rho GAP domain that disrupts the actin cytoskeleton and interference of phagocytosis. The C-terminal of ExoS contains an ADP-ribosyltransferase domain, which elicits a cytotoxic phenotype in cultured cells.
    Molekulargewicht
    48 kDa
    UniProt
    Q51449
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