Factor VII Produkte
(Coagulation Factor VII (F7))
Kategorien
This gene encodes coagulation factor VII which is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis. Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Defects in this gene can cause coagulopathy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012].
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Ausgewählte Factor VII Kategorien
Factor VII Antikörper
High quality antibodies with extensive validation data.
Factor VII ELISA Kits
Reliable ELISA kits for a wide range of species.
Factor VII Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene Factor VII Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse
Applikation
WB, IHC, IP, ICC
Validierungen
- (4)
Kat. Nr.
ABIN7440011
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IP
Validierungen
- (3)
Kat. Nr.
ABIN515448
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, PLA
Validierungen
- (3)
Kat. Nr.
ABIN515449
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene Factor VII ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (6)
Kat. Nr.
ABIN6574291
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (3)
Kat. Nr.
ABIN6574292
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN6963490
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene Factor VII Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1353322
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1353324
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7395107
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren Factor VII Produkten
: "Human acute Chagas disease: changes in factor VII, activated protein C and hepatic enzymes from patients of oral outbreaks in Pará State (Brazilian Amazon)." in: Memórias do Instituto Oswaldo Cruz, Vol. 115, pp. e190364, (2020) (PubMed).: "Targeting Coagulation Factor Xa Promotes Regression of Advanced Atherosclerosis in Apolipoprotein-E Deficient Mice." in: Scientific reports, Vol. 9, Issue 1, pp. 3909, (2019) (PubMed).
: "Loss of Sirt3 accelerates arterial thrombosis by increasing formation of neutrophil extracellular traps and plasma tissue factor activity." in: Cardiovascular research, Vol. 114, Issue 8, pp. 1178-1188, (2018) (PubMed).
: "Ex vivo simulation of cardiopulmonary bypass with human blood for hemocompatibility testing." in: Perfusion, Vol. 31, Issue 5, pp. 376-83, (2016) (PubMed).
: "TRUST trial: BAY 86-6150 use in haemophilia with inhibitors and assessment for immunogenicity." in: Haemophilia : the official journal of the World Federation of Hemophilia, Vol. 22, Issue 6, pp. 873-879, (2016) (PubMed).
: "In vitro uptake of recombinant factor VIIa by megakaryocytes with subsequent production of platelets containing functionally active drug." in: British journal of haematology, (2016) (PubMed).
: "Monocytes regulate systemic coagulation and inflammation in abdominal sepsis." in: American journal of physiology. Heart and circulatory physiology, Vol. 308, Issue 5, pp. H540-7, (2015) (PubMed).
: "Coagulation factor VII is regulated by androgen receptor in breast cancer." in: Experimental cell research, Vol. 331, Issue 1, pp. 239-50, (2015) (PubMed).
: "Novel antibody against a glutamic acid-rich human fibrinogen-like protein 2-derived peptide near Ser91 inhibits hfgl2 prothrombinase activity." in: PLoS ONE, Vol. 9, Issue 4, pp. e94551, (2014) (PubMed).
: "Oestrogenic repression of human coagulation factor VII expression mediated through an oestrogen response element sequence motif in the promoter region." in: Human molecular genetics, Vol. 11, Issue 7, pp. 723-31, (2002) (PubMed).
Synonyme und alternative Namen zu Factor VII
coagulation factor VII (F7), coagulation factor VII (f7), serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1 (Serpinc1), coagulation factor VII (CpipJ_CPIJ009142), coagulation factor VII (CpipJ_CPIJ010295), coagulation factor VII (CpipJ_CPIJ020127), coagulation factor VII (fa7), coagulation factor 7 (serum prothrombin conversion accelerator) S homeolog (f7.S), AI114908, AI132620, At-3, At3, ATIII, Cf7, F7, f7, FVII, LOC100223776, mfVII, SPCA, wu:fb59f04, zgc:109870Bezeichner auf Proteinebene für Factor VII
- coagulation factor VII
- serum prothrombin conversion accelerator
- clotting factor
- FVII coagulation protein
- eptacog alfa
- proconvertin
- anti-thrombin 3
- antithrombin
- antithrombin-III
- serine (or cysteine) proteinase inhibitor, clade C (antithrombin), member 1
- serpin C1
- serpin peptidase inhibitor, clade C, member 1
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