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Factor VIII Produkte

(Coagulation Factor VIII (F8))

Kategorien

This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation\; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder. [provided by RefSeq, Jul 2008].

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Ausgewählte Factor VIII Kategorien

Factor VIII Antikörper

High quality antibodies with extensive validation data.

Factor VIII ELISA Kits

Reliable ELISA kits for a wide range of species.

Factor VIII Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene Factor VIII Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC, IP, ICC
Validierungen
  • (7)
Kat. Nr. ABIN7438070
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, IP, ICC
Validierungen
  • (7)
Kat. Nr. ABIN7434263
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Mouse
Applikation WB, IHC, IP, ICC
Validierungen
  • (4)
Kat. Nr. ABIN7434266
Menge 100 μL
Datenblatt Datenblatt

Empfohlene Factor VIII ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6963573
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6965897
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6962842
Menge 96 tests
Datenblatt Datenblatt

Empfohlene Factor VIII Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1353327
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1353326
Menge 25 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7401242
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren Factor VIII Produkten

Li, Wen, Su, Yang, Han, Fan: "Local suture ligation-assisted percutaneous sclerotherapy for Kasabach-Merritt phenomenon-associated kaposiform haemangioendothelioma." in: Oncology letters, Vol. 17, Issue 1, pp. 981-989, (2019) (PubMed).

Hu, Wang, Leng, Hu, Shen, Song: "Heparanase mediates vascular endothelial growth factor gene transcription in high-glucose human retinal microvascular endothelial cells." in: Molecular vision, Vol. 23, pp. 579-587, (2018) (PubMed).

Li, Zhang, Cao, Li, Ye, Shi, Wang, Sun, Wang, Jia, Wang: "Tanshinone IIA and Astragaloside IV promote the angiogenesis of mesenchymal stem cell-derived endothelial cell-like cells via upregulation of Cx37, Cx40 and Cx43." in: Experimental and therapeutic medicine, Vol. 15, Issue 2, pp. 1847-1854, (2018) (PubMed).

Song, Li, Yu: "Effects of preserving different veins on flow-through flap survival: An experimental study." in: Experimental and therapeutic medicine, Vol. 11, Issue 1, pp. 318-324, (2016) (PubMed).

Lei, Peng, Samuel, Zhang, Wu, Wang, Li, Liu: "A simple and biosafe method for isolation of human umbilical vein endothelial cells." in: Analytical biochemistry, Vol. 508, pp. 15-8, (2016) (PubMed).

Kyostio-Moore, Berthelette, Piraino, Sookdeo, Nambiar, Jackson, Burnham, ORiordan, Cheng, Armentano: "The impact of minimally oversized adeno-associated viral vectors encoding human factor VIII on vector potency in vivo." in: Molecular therapy. Methods & clinical development, Vol. 3, pp. 16006, (2016) (PubMed).

Zhu, Hua, Zhu, Li, Wang, Yu, Li: "Stereoselective Regulation of P-gp Activity by Clausenamide Enantiomers in Caco-2, KB/KBv and Brain Microvessel Endothelial Cells." in: PLoS ONE, Vol. 10, Issue 8, pp. e0135866, (2016) (PubMed).

Periayah, Halim, Mat Saad, Yaacob, Hussein, Abdul Karim, Abdul Rashid, Ujang: "Effect of the Novel Biodegradable N, O-Carboxymethylchitosan and Oligo-Chitosan on the Platelet Thrombogenicity Cascade in von Willebrand Disease." in: Thrombosis research, Vol. 136, Issue 3, pp. 625-33, (2015) (PubMed).

Li, Cao, Zeng, Liang, Xue, Xi, Zhou, Jiang: "Angiotensin-converting enzyme 2/angiotensin-(1-7)/Mas axis prevents lipopolysaccharide-induced apoptosis of pulmonary microvascular endothelial cells by inhibiting JNK/NF-?B pathways." in: Scientific reports, Vol. 5, pp. 8209, (2015) (PubMed).

Zhang, Shen: "A ferulic acid (FA)-eluting system for biodegradable magnesium stent: Cells response of HUVECs." in: Journal of biomedical materials research. Part A, Vol. 103, Issue 8, pp. 2758-69, (2015) (PubMed).

Synonyme und alternative Namen zu Factor VIII

coagulation factor VIIi (f7i), coagulation factor VIII (F8), coagulation factor VIII, procoagulant component (F8), AHF, Cf-8, Cf8, DXS1253E, F8B, F8C, fb61d02, FVIII, HEMA, wu:fb61d02

Bezeichner auf Proteinebene für Factor VIII

  • Factor VIII
  • procoagulant component
  • antihemophilic factor
  • coagulation factor VIII
  • coagulation factor VIIIc
  • factor VIII F8B
  • coagulation factor VIII, procoagulant component (hemophilia A)
  • factor VIII
  • coagulation co-factor
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