FANCA Produkte
(Fanconi Anemia Group A Protein (FANCA))
Kategorien
The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity\; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group A. Alternative splicing results in multiple transcript variants encoding different isoforms. Mutations in this gene are the most common cause of Fanconi anemia. [provided by RefSeq, Jul 2008].
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Ausgewählte FANCA Kategorien
FANCA Antikörper
High quality antibodies with extensive validation data.
FANCA ELISA Kits
Reliable ELISA kits for a wide range of species.
FANCA Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene FANCA Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA
Validierungen
- (1)
- (2)
Kat. Nr.
ABIN129606
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IF, IHC (p), ICC
Validierungen
- (3)
Kat. Nr.
ABIN2856901
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IF
Validierungen
- (2)
Kat. Nr.
ABIN515503
Menge
50 μg
Datenblatt
Datenblatt
Empfohlene FANCA ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6966641
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Validierungen
Kat. Nr.
ABIN1132955
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene FANCA Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1353621
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Baculovirus infected Insect Cells
Validierungen
Kat. Nr.
ABIN7317446
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3092529
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren FANCA Produkten
: "The Fanconi anemia pathway has a dual function in Dickkopf-1 transcriptional repression." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Issue 6, pp. 2152-7, (2014) (PubMed).: "Histone chaperone activity of Fanconi anemia proteins, FANCD2 and FANCI, is required for DNA crosslink repair." in: The EMBO journal, Vol. 31, Issue 17, pp. 3524-36, (2012) (PubMed).
: "RAD18-mediated ubiquitination of PCNA activates the Fanconi anemia DNA repair network." in: The Journal of cell biology, Vol. 191, Issue 2, pp. 249-57, (2011) (PubMed).
: "Differential roles for DNA polymerases eta, zeta, and REV1 in lesion bypass of intrastrand versus interstrand DNA cross-links." in: Molecular and cellular biology, Vol. 30, Issue 5, pp. 1217-30, (2010) (PubMed).
: "Upregulated ATM gene expression and activated DNA crosslink-induced damage response checkpoint in Fanconi anemia: implications for carcinogenesis." in: Molecular medicine (Cambridge, Mass.), Vol. 14, Issue 3-4, pp. 167-74, (2008) (PubMed).
: "Identification of the FANCI protein, a monoubiquitinated FANCD2 paralog required for DNA repair." in: Cell, Vol. 129, Issue 2, pp. 289-301, (2007) (PubMed).
: "Oxidative stress/damage induces multimerization and interaction of Fanconi anemia proteins." in: The Journal of biological chemistry, Vol. 279, Issue 29, pp. 30053-9, (2004) (PubMed).
Synonyme und alternative Namen zu FANCA
Fanconi anemia complementation group A (FANCA), Fanconi anemia, complementation group A (Fanca), AW208693, FA, FA-H, FA1, FAA, FACA, FAH, FANCHBezeichner auf Proteinebene für FANCA
- Fanconi anemia group A protein
- Fanconi anemia, complementation group H
- Fanconi anemia, type 1
- Fanconi anemia group A protein homolog
Haben Sie etwas anderes gesucht?
- FAN1
- Family with Sequence Similarity 92, Member A1
- Family with Sequence Similarity 58, Member B
- Family with Sequence Similarity 50, Member A
- Family with Sequence Similarity 46, Member B
- Family with Sequence Similarity 220, Member A
- Family with Sequence Similarity 212, Member A
- Family with Sequence Similarity 102, Member B
- Family with Sequence Similarity 102, Member A
- FAM9C
- FAM9B
- FAM98C
- FAM98B
- FAM98A
- FAM96B
- FAM96A
- FAM92B
- FAM91A1
- Fam90a9
- Fam90a8
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