FANCL Produkte
(Fanconi Anemia, Complementation Group L (FANCL))
Kategorien
The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity\; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group L. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
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Ausgewählte FANCL Kategorien
FANCL Antikörper
High quality antibodies with extensive validation data.
FANCL ELISA Kits
Reliable ELISA kits for a wide range of species.
FANCL Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene FANCL Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IF, IP
Validierungen
- (6)
Kat. Nr.
ABIN949415
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, IHC
Validierungen
- (3)
Kat. Nr.
ABIN7262741
Menge
200 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
ELISA, IHC, IF
Validierungen
- (2)
Kat. Nr.
ABIN7151021
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene FANCL ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Validierungen
Kat. Nr.
ABIN1131086
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Validierungen
Kat. Nr.
ABIN1131087
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene FANCL Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1353638
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Baculovirus infected Insect Cells, Insect cells (Sf9)
Validierungen
Kat. Nr.
ABIN6699823
Menge
50 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren FANCL Produkten
: "Basal level of FANCD2 monoubiquitination is required for the maintenance of a sufficient number of licensed-replication origins to fire at a normal rate." in: Oncotarget, Vol. 5, Issue 5, pp. 1326-37, (2014) (PubMed).: "FAVL elevation in human tumors disrupts Fanconi anemia pathway signaling and promotes genomic instability and tumor growth." in: The Journal of clinical investigation, Vol. 120, Issue 5, pp. 1524-34, (2010) (PubMed).
: "Mutational analysis of FANCL, FANCM and the recently identified FANCI suggests that among the 13 known Fanconi Anemia genes, only FANCD1/BRCA2 plays a major role in high-risk breast cancer ..." in: Carcinogenesis, Vol. 30, Issue 11, pp. 1898-902, (2009) (PubMed).
: "FANCI binds branched DNA and is monoubiquitinated by UBE2T-FANCL." in: The Journal of biological chemistry, Vol. 284, Issue 35, pp. 23182-6, (2009) (PubMed).
: "Polymorphic variants in hereditary pancreatic cancer genes are not associated with pancreatic cancer risk." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 18, Issue 9, pp. 2549-52, (2009) (PubMed).
: "Hypermethylation of the FANCC and FANCL promoter regions in sporadic acute leukaemia." in: Cellular oncology : the official journal of the International Society for Cellular Oncology, Vol. 30, Issue 4, pp. 299-306, (2008) (PubMed).
Synonyme und alternative Namen zu FANCL
Fanconi anemia complementation group L (FANCL), Fanconi anemia, complementation group L (Fancl), 2010322C19Rik, AW554273, B230118H11Rik, FAAP43, gcd, PHF9, Phf9, POG, PogBezeichner auf Proteinebene für FANCL
- E3 ubiquitin-protein ligase FANCL
- PHD finger protein 9
- fanconi anemia group L protein
- fanconi anemia-associated polypeptide of 43 kDa
- fanconi anemia group L protein homolog
- germ cell deficient
- proliferation of germ cells protein
Haben Sie etwas anderes gesucht?
- FANCI
- FANCG
- FANCF
- FANCE
- FANCD2
- FANCC
- FANCB
- FANCA
- FAN1
- Family with Sequence Similarity 92, Member A1
- Family with Sequence Similarity 58, Member B
- Family with Sequence Similarity 50, Member A
- Family with Sequence Similarity 46, Member B
- Family with Sequence Similarity 220, Member A
- Family with Sequence Similarity 212, Member A
- Family with Sequence Similarity 102, Member B
- Family with Sequence Similarity 102, Member A
- FAM9C
- FAM9B
- FAM98C
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