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Fascin Produkte

(Fascin (FSCN1))
This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15. [provided by RefSeq, Sep 2011].

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Ausgewählte Fascin Kategorien

Fascin Antikörper

High quality antibodies with extensive validation data.

Fascin ELISA Kits

Reliable ELISA kits for a wide range of species.

Fascin Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene Fascin Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC, FACS, IF, StM
Validierungen
  • (7)
Kat. Nr. ABIN6940607
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human, Rat
Applikation WB, IHC, FACS, IF, StM
Validierungen
  • (6)
Kat. Nr. ABIN6940609
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Mouse, Rat
Applikation WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validierungen
  • (5)
Kat. Nr. ABIN728293
Menge 100 μL
Datenblatt Datenblatt

Empfohlene Fascin ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN6955706
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Guinea Pig
Analytical Method Quantitative Competition ELISA
Validierungen
Kat. Nr. ABIN776822
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rabbit
Analytical Method Quantitative Competition ELISA
Validierungen
Kat. Nr. ABIN774867
Menge 96 tests
Datenblatt Datenblatt

Empfohlene Fascin Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7122887
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1989775
Menge 25 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN2129307
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren Fascin Produkten

Zhang, Zhao, Zhang, Hao, Yu, Min, Li, Ma, Chen, Yi, Tang, Meng, Liu, Wang, Shen, Zhang: "Decrease in male mouse fertility by hydrogen sulfide and/or ammonia can Be inheritable." in: Chemosphere, Vol. 194, pp. 147-157, (2018) (PubMed).

Yang, Teng, Han, Li, Yue, Wang: "Clinical significance of fascin-1 and laminin-5 in non-small cell lung cancer." in: Genetics and molecular research : GMR, Vol. 16, Issue 2, (2017) (PubMed).

Barnawi, Al-Khaldi, Majed Sleiman, Sarkar, Al-Dhfyan, Al-Mohanna, Ghebeh, Al-Alwan: "Fascin Is Critical for the Maintenance of Breast Cancer Stem Cell Pool Predominantly via the Activation of the Notch Self-Renewal Pathway." in: Stem cells (Dayton, Ohio), Vol. 34, Issue 12, pp. 2799-2813, (2016) (PubMed).

Osanai, Lee: "The retinoic acid-metabolizing enzyme CYP26A1 upregulates fascin and promotes the malignant behavior of breast carcinoma cells." in: Oncology reports, Vol. 34, Issue 2, pp. 850-8, (2015) (PubMed).

Król, Mucha, Majchrzak, Homa, Bulkowska, Majewska, Gajewska, Pietrzak, Perszko, Romanowska, Paw?owski, Manuali, Hellmen, Motyl: "Macrophages mediate a switch between canonical and non-canonical Wnt pathways in canine mammary tumors." in: PLoS ONE, Vol. 9, Issue 1, pp. e83995, (2014) (PubMed).

Al-Masri, El Eter, Tayel, Zamil: "Differential associations of circulating peroxiredoxins levels with indicators of glycemic control in type 2 diabetes mellitus." in: European review for medical and pharmacological sciences, Vol. 18, Issue 5, pp. 710-6, (2014) (PubMed).

Jiang, Wang, Chen: "Overexpression of FOXM1 is associated with metastases of nasopharyngeal carcinoma." in: Upsala journal of medical sciences, Vol. 119, Issue 4, pp. 324-32, (2014) (PubMed).

Majchrzak, Lo Re, Gajewska, Bulkowska, Homa, Paw?owski, Motyl, Murphy, Król: "Migrastatin analogues inhibit canine mammary cancer cell migration and invasion." in: PLoS ONE, Vol. 8, Issue 10, pp. e76789, (2013) (PubMed).

Teng, Xu, Yue, Ma, Zhang, Zhao, Guo, Zhang, Gu, Wang: "Serological investigation of the clinical significance of fascin in non-small-cell lung cancer." in: Lung cancer (Amsterdam, Netherlands), Vol. 82, Issue 2, pp. 346-52, (2013) (PubMed).

Law, Li, Chou, Chen, Chan: "Hyaluronic acid-dependent protection in H9C2 cardiomyocytes: a cell model of heart ischemia-reperfusion injury and treatment." in: Toxicology, Vol. 303, pp. 54-71, (2013) (PubMed).

Synonyme und alternative Namen zu Fascin

singed (sn), fascin actin-bundling protein 1 (fscn1), fascin actin-bundling protein 1a (fscn1a), fascin actin-bundling protein 1 (Fscn1), fascin actin-bundling protein 1 L homeolog (fscn1.L), fascin actin-bundling protein 1 (FSCN1), AI663989, CG1536, CG15331, CG32858, Dmel\\CG32858, Fan1, FAN1, Fascin, fascin, fascin-1, fs(1)A1057, fs(1)K418, fs(1)K473, fs(1)K743, fs(1)K1421, fs(1)M45, fscn, fscn1, HSN, MGC75811, p55, sb:cb589, SN, Sn, snl, SNL, zgc:153632

Bezeichner auf Proteinebene für Fascin

  • CG32858-PA
  • CG32858-PB
  • CG32858-PD
  • CG32858-PE
  • CG32858-PF
  • CG32858-PG
  • fascin
  • sn-PA
  • sn-PB
  • sn-PD
  • sn-PE
  • sn-PF
  • sn-PG
  • fascin-1
  • fascin 1
  • singed-like protein
  • 55 kDa actin-bundling protein
  • singed-like (fascin homolog, sea urchin)
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