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F2RL1 Produkte

(Coagulation Factor II (thrombin) Receptor-Like 1 (F2RL1))
Coagulation factor II (thrombin) receptor-like 1 (F2RL1) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL1 is also a member of the protease-activated receptor family. It is activated by trypsin, but not by thrombin. It is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. The F2RL1 gene contains two exons and is widely expressed in human tissues. The predicted protein sequence is 83% identical to the mouse receptor sequence. [provided by RefSeq, Jul 2008].

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Ausgewählte F2RL1 Kategorien

F2RL1 Antikörper

High quality antibodies with extensive validation data.

F2RL1 ELISA Kits

Reliable ELISA kits for a wide range of species.

F2RL1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene F2RL1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, IHC, IF, ICC
Validierungen
  • (5)
Kat. Nr. ABIN7043075
Menge 25 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC
Validierungen
  • (3)
Kat. Nr. ABIN7101760
Menge 20 μL
Datenblatt Datenblatt
Reaktivität Human, Monkey
Applikation IHC, IHC (p)
Validierungen
  • (3)
Kat. Nr. ABIN1049232
Menge 50 μg
Datenblatt Datenblatt

Empfohlene F2RL1 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (6)
  • (1)
Kat. Nr. ABIN6954858
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6965879
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6965880
Menge 96 tests
Datenblatt Datenblatt

Empfohlene F2RL1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (2)
Kat. Nr. ABIN7491637
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7122416
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1353314
Menge 10 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren F2RL1 Produkten

Klinngam, Fu, Janga, Edman, Hamm-Alvarez: "Cathepsin S Alters the Expression of Pro-Inflammatory Cytokines and MMP-9, Partially through Protease-Activated Receptor-2, in Human Corneal Epithelial Cells." in: International journal of molecular sciences, Vol. 19, Issue 11, (2019) (PubMed).

Cheng, Fiez-Vandal, Schlenker, Edman, Aggeler, Brown, Brown, Cooke, Dumelin, Doré, Geschwindner, Grebner, Hermansson, Jazayeri, Johansson, Leong, Prihandoko, Rappas, Soutter, Snijder, Sundström et al.: "Structural insight into allosteric modulation of protease-activated receptor 2. ..." in: Nature, Vol. 545, Issue 7652, pp. 112-115, (2017) (PubMed).

Quanjun, Qingyu, Qiliang, Liqun, Jinmei, Ziquan, Shike: "Effect and mechanism of PAR-2 on the proliferation of esophageal cancer cells." in: European review for medical and pharmacological sciences, Vol. 20, Issue 22, pp. 4688-4696, (2017) (PubMed).

Kouzaki, Matsumoto, Kato, Tojima, Shimizu, Shimizu: "Epithelial Cell-Derived Cytokines Contribute to the Pathophysiology of Eosinophilic Chronic Rhinosinusitis." in: Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, Vol. 36, Issue 3, pp. 169-79, (2016) (PubMed).

Pan, Zhang, Zang, Tan, Jin: "Hydroxysafflor yellow A inhibits TGF-β1-induced activation of human fetal lung fibroblasts in vitro." in: The Journal of pharmacy and pharmacology, Vol. 68, Issue 10, pp. 1320-30, (2016) (PubMed).

Rohan, Smetakova, Kukal, Rusina, Matej: "Proteinase-activated receptor 2 and disease biomarkers in cerebrospinal fluid in cases with autopsy-confirmed prion diseases and other neurodegenerative diseases." in: BMC neurology, Vol. 15, pp. 50, (2015) (PubMed).

Viodé, Lejeune, Turlier, Rouquier, Casas, Mengeaud, Redoulès, Schmitt: "Cathepsin S, a new pruritus biomarker in clinical dandruff/seborrhoeic dermatitis evaluation." in: Experimental dermatology, Vol. 23, Issue 4, pp. 274-5, (2014) (PubMed).

Mat?j, Sm?táková, Vašáková, Nováková, Sterclová, Kukal, Olejár: "PAR-2, IL-4R, TGF-? and TNF-? in bronchoalveolar lavage distinguishes extrinsic allergic alveolitis from sarcoidosis." in: Experimental and therapeutic medicine, Vol. 8, Issue 2, pp. 533-538, (2014) (PubMed).

Vasakova, Sterclova, Stranska, Mandakova, Skibova, Matej: "Biomarkers of fibroproliferative healing in fibrosing idiopathic interstitial pneumonias." in: The open respiratory medicine journal, Vol. 6, pp. 160-4, (2013) (PubMed).

Yau, Liu, Fairlie: "Toward drugs for protease-activated receptor 2 (PAR2)." in: Journal of medicinal chemistry, Vol. 56, Issue 19, pp. 7477-97, (2013) (PubMed).

Synonyme und alternative Namen zu F2RL1

Proteinase-activated receptor 2 (par2), F2R like trypsin receptor 1 (F2RL1), coagulation factor II (thrombin) receptor-like 1 (F2rl1), F2R like trypsin receptor 1 (F2rl1), Gpcr11, GPR11, PAR-2, Par-2, par2, PAR2, Par2

Bezeichner auf Proteinebene für F2RL1

  • Proteinase-activated receptor 2
  • G-protein coupled receptor 11
  • coagulation factor II receptor-like 1
  • protease-activated receptor 2
  • proteinase-activated receptor 2
  • thrombin receptor-like 1
  • Protease-activated receptor-2
  • proteinase-activated receptor-2
  • Proteinase-activated receptor-2 G protein-coupled receptor 11
  • Proteinase-activated receptor-2, G protein-coupled receptor 11
  • PAR-2
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