FBXO32 Produkte
(F-Box Protein 32 (FBXO32))
Kategorien
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2011].
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Ausgewählte FBXO32 Kategorien
FBXO32 Antikörper
High quality antibodies with extensive validation data.
FBXO32 ELISA Kits
Reliable ELISA kits for a wide range of species.
FBXO32 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene FBXO32 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB
Validierungen
- (5)
Kat. Nr.
ABIN3017562
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, IHC, ELISA
Validierungen
- (3)
Kat. Nr.
ABIN7251817
Menge
200 μL
Datenblatt
Datenblatt
Reaktivität
Human, Rat
Applikation
WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro)
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN747698
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene FBXO32 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6966624
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6966625
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6966626
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene FBXO32 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN1353808
Menge
25 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7408129
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3080206
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren FBXO32 Produkten
: "FBXO32 suppresses breast cancer tumorigenesis through targeting KLF4 to proteasomal degradation." in: Oncogene, Vol. 36, Issue 23, pp. 3312-3321, (2017) (PubMed).: "Hindlimb Immobilization, But Not Castration, Induces Reduction of Undercarboxylated Osteocalcin Associated With Muscle Atrophy in Rats." in: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 31, Issue 11, pp. 1967-1978, (2016) (PubMed).
: "Myostatin induces degradation of sarcomeric proteins through a Smad3 signaling mechanism during skeletal muscle wasting." in: Molecular endocrinology (Baltimore, Md.), Vol. 25, Issue 11, pp. 1936-49, (2011) (PubMed).
: "The muscle-specific ubiquitin ligase atrogin-1/MAFbx mediates statin-induced muscle toxicity." in: The Journal of clinical investigation, Vol. 117, Issue 12, pp. 3940-51, (2007) (PubMed).
Synonyme und alternative Namen zu FBXO32
F-box protein 32 (fbxo32), F-box protein 32 (FBXO32), F-box protein 32 (Fbxo32), 4833442G10Rik, AI430017, ATROGIN1, Atrogin1, Fbx32, Gm20361, MAFbx, MGC56479, zgc:56479Bezeichner auf Proteinebene für FBXO32
- F-box only protein 32
- atrogin-1
- F-box protein 32
- F-box only protein 32-like
- atrogin 1
- muscle atrophy F-box protein
- atrophy gene 1
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