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FBXO4 Produkte

(F-Box Protein 4 (FBXO4))

Kategorien

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternative splicing of this gene generates 2 transcript variants. [provided by RefSeq, Jul 2008].

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Ausgewählte FBXO4 Kategorien

FBXO4 Antikörper

High quality antibodies with extensive validation data.

FBXO4 ELISA Kits

Reliable ELISA kits for a wide range of species.

FBXO4 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene FBXO4 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA, IP, IHC
Validierungen
  • (4)
Kat. Nr. ABIN7152437
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IP
Validierungen
  • (3)
Kat. Nr. ABIN525677
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation ELISA, IHC
Validierungen
  • (2)
Kat. Nr. ABIN7152439
Menge 100 μg
Datenblatt Datenblatt

Empfohlene FBXO4 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Sheep
Analytical Method
Validierungen
Kat. Nr. ABIN1774002
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Competition ELISA
Validierungen
Kat. Nr. ABIN1743097
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Dog
Analytical Method
Validierungen
Kat. Nr. ABIN1769106
Menge 96 tests
Datenblatt Datenblatt

Empfohlene FBXO4 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1353823
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr. ABIN3079809
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Mouse
Source Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr. ABIN3126035
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren FBXO4 Produkten

Gong, Zack, Morris, Lin, Hukkelhoven, Raheja, Tan, Turcan, Veeriah, Meng, Viale, Schumacher, Palmedo, Beroukhim, Chan: "Pan-cancer genetic analysis identifies PARK2 as a master regulator of G1/S cyclins." in: Nature genetics, Vol. 46, Issue 6, pp. 588-94, (2014) (PubMed).

Yonekawa, Yang, Counter: "PinX1 localizes to telomeres and stabilizes TRF1 at mitosis." in: Molecular and cellular biology, Vol. 32, Issue 8, pp. 1387-95, (2012) (PubMed).

Barbash, Lee, Diehl: "Phosphorylation-dependent regulation of SCF(Fbx4) dimerization and activity involves a novel component, 14-3-3ɛ" in: Oncogene, (2011) (PubMed).

Pontano, Aggarwal, Barbash, Brown, Bassing, Diehl: "Genotoxic stress-induced cyclin D1 phosphorylation and proteolysis are required for genomic stability." in: Molecular and cellular biology, Vol. 28, Issue 23, pp. 7245-58, (2008) (PubMed).

Barbash, Zamfirova, Lin, Chen, Yang, Nakagawa, Lu, Rustgi, Diehl: "Mutations in Fbx4 inhibit dimerization of the SCF(Fbx4) ligase and contribute to cyclin D1 overexpression in human cancer." in: Cancer cell, Vol. 14, Issue 1, pp. 68-78, (2008) (PubMed).

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Lee, Perrem, Harper, Lu, Zhou: "The F-box protein FBX4 targets PIN2/TRF1 for ubiquitin-mediated degradation and regulates telomere maintenance." in: The Journal of biological chemistry, Vol. 281, Issue 2, pp. 759-68, (2006) (PubMed).

Lin, Barbash, Kumar, Weber, Harper, Klein-Szanto, Rustgi, Fuchs, Diehl: "Phosphorylation-dependent ubiquitination of cyclin D1 by the SCF(FBX4-alphaB crystallin) complex." in: Molecular cell, Vol. 24, Issue 3, pp. 355-66, (2006) (PubMed).

den Engelsman, Keijsers, de Jong, Boelens: "The small heat-shock protein alpha B-crystallin promotes FBX4-dependent ubiquitination." in: The Journal of biological chemistry, Vol. 278, Issue 7, pp. 4699-704, (2003) (PubMed).

Kennedy, Mohler, Shanebeck, Baum, Picha, Otten-Evans, Janeway, Grabstein: "Induction of B cell costimulatory function by recombinant murine CD40 ligand." in: European journal of immunology, Vol. 24, Issue 1, pp. 116-23, (1994) (PubMed).

Synonyme und alternative Namen zu FBXO4

F-box protein 4 (FBXO4), F-box protein 4 (Fbxo4), F-box protein 4 (fbxo4), F-box protein 4 L homeolog (fbxo4.L), 1700096C12Rik, AI851261, AW494535, FBX4, Fbx4, fbx4, FBXO4, si:dkey-46a10.2

Bezeichner auf Proteinebene für FBXO4

  • F-box only protein 4
  • F-box protein Fbx4
  • F-box protein 4
  • F-box only protein 4-like
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