FBXW4 Produkte
(F-Box and WD Repeat Domain Containing 4 (FBXW4))
Kategorien
This gene is a member of the F-box/WD-40 gene family, which recruit specific target proteins through their WD-40 protein-protein binding domains for ubiquitin mediated degradation. In mouse, a highly similar protein is thought to be responsible for maintaining the apical ectodermal ridge of developing limb buds\; disruption of the mouse gene results in the absence of central digits, underdeveloped or absent metacarpal/metatarsal bones and syndactyly. This phenotype is remarkably similar to split hand-split foot malformation in humans, a clinically heterogeneous condition with a variety of modes of transmission. An autosomal recessive form has been mapped to the chromosomal region where this gene is located, and complex rearrangements involving duplications of this gene and others have been associated with the condition. A pseudogene of this locus has been mapped to one of the introns of the BCR gene on chromosome 22. [provided by RefSeq, Jul 2008].
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Ausgewählte FBXW4 Kategorien
FBXW4 Antikörper
High quality antibodies with extensive validation data.
FBXW4 ELISA Kits
Reliable ELISA kits for a wide range of species.
FBXW4 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene FBXW4 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
ELISA, WB, IHC
Validierungen
- (2)
Kat. Nr.
ABIN7152503
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB
Validierungen
- (2)
- (1)
Kat. Nr.
ABIN1881340
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
ELISA, WB
Validierungen
- (1)
Kat. Nr.
ABIN562867
Menge
50 μL
Datenblatt
Datenblatt
Empfohlene FBXW4 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6966623
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Competition ELISA
Validierungen
Kat. Nr.
ABIN1743136
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Sheep
Analytical Method
Validierungen
Kat. Nr.
ABIN1774041
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene FBXW4 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1353871
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3080125
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3130394
Menge
1 mg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren FBXW4 Produkten
: "Frequency of genomic rearrangements involving the SHFM3 locus at chromosome 10q24 in syndromic and non-syndromic split-hand/foot malformation." in: American journal of medical genetics. Part A, Vol. 140, Issue 13, pp. 1375-83, (2006) (PubMed).: "The DNA sequence and comparative analysis of human chromosome 10. ..." in: Nature, Vol. 429, Issue 6990, pp. 375-81, (2004) (PubMed).
: "A genomic rearrangement resulting in a tandem duplication is associated with split hand-split foot malformation 3 (SHFM3) at 10q24. ..." in: Human molecular genetics, Vol. 12, Issue 16, pp. 1959-71, (2003) (PubMed).
: "cDNA cloning and expression analysis of new members of the mammalian F-box protein family." in: Genomics, Vol. 67, Issue 1, pp. 40-7, (2000) (PubMed).
Synonyme und alternative Namen zu FBXW4
F-box and WD repeat domain containing 4 (fbxw4), F-box and WD repeat domain containing 4 (FBXW4), F-box and WD repeat domain containing 4 (Fbxw4), F-box and WD-40 domain protein 4 (Fbxw4), dac, DAC, Dac, dactylin, dactylyn, FBW4, Fbw4, FBWD4, FBXW4, hag, hagoromo, SHFM3, SHSF3, wu:fk63g06Bezeichner auf Proteinebene für FBXW4
- F-box/WD repeat-containing protein 4
- dactylaplasia
- fk63g06
- F-box and WD repeat domain containing 4
- F-box and WD-40 domain protein 4
- F-box and WD-40 domain-containing protein 4
- F-box/WD repeat protein 4
- dactylin
- F-box protein Fbw4
- protein hagoromo
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