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FBXW4 Produkte

(F-Box and WD Repeat Domain Containing 4 (FBXW4))

Kategorien

This gene is a member of the F-box/WD-40 gene family, which recruit specific target proteins through their WD-40 protein-protein binding domains for ubiquitin mediated degradation. In mouse, a highly similar protein is thought to be responsible for maintaining the apical ectodermal ridge of developing limb buds\; disruption of the mouse gene results in the absence of central digits, underdeveloped or absent metacarpal/metatarsal bones and syndactyly. This phenotype is remarkably similar to split hand-split foot malformation in humans, a clinically heterogeneous condition with a variety of modes of transmission. An autosomal recessive form has been mapped to the chromosomal region where this gene is located, and complex rearrangements involving duplications of this gene and others have been associated with the condition. A pseudogene of this locus has been mapped to one of the introns of the BCR gene on chromosome 22. [provided by RefSeq, Jul 2008].

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Ausgewählte FBXW4 Kategorien

FBXW4 Antikörper

High quality antibodies with extensive validation data.

FBXW4 ELISA Kits

Reliable ELISA kits for a wide range of species.

FBXW4 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene FBXW4 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation ELISA, WB, IHC
Validierungen
  • (2)
Kat. Nr. ABIN7152503
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB
Validierungen
  • (2)
  • (1)
Kat. Nr. ABIN1881340
Menge 400 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation ELISA, WB
Validierungen
  • (1)
Kat. Nr. ABIN562867
Menge 50 μL
Datenblatt Datenblatt

Empfohlene FBXW4 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6966623
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Competition ELISA
Validierungen
Kat. Nr. ABIN1743136
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Sheep
Analytical Method
Validierungen
Kat. Nr. ABIN1774041
Menge 96 tests
Datenblatt Datenblatt

Empfohlene FBXW4 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1353871
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr. ABIN3080125
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Mouse
Source Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr. ABIN3130394
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren FBXW4 Produkten

Everman, Morgan, Lyle, Laughridge, Bamshad, Clarkson, Colby, Gurrieri, Innes, Roberson, Schrander-Stumpel, van Bokhoven, Antonarakis, Schwartz: "Frequency of genomic rearrangements involving the SHFM3 locus at chromosome 10q24 in syndromic and non-syndromic split-hand/foot malformation." in: American journal of medical genetics. Part A, Vol. 140, Issue 13, pp. 1375-83, (2006) (PubMed).

Deloukas, Earthrowl, Grafham, Rubenfield, French, Steward, Sims, Jones, Searle, Scott, Howe, Hunt, Andrews, Gilbert, Swarbreck, Ashurst, Taylor, Battles, Bird, Ainscough, Almeida, Ashwell, Ambrose et al.: "The DNA sequence and comparative analysis of human chromosome 10. ..." in: Nature, Vol. 429, Issue 6990, pp. 375-81, (2004) (PubMed).

de Mollerat, Gurrieri, Morgan, Sangiorgi, Everman, Gaspari, Amiel, Bamshad, Lyle, Blouin, Allanson, Le Marec, Wilson, Braverman, Radhakrishna, Delozier-Blanchet, Abbott, Elghouzzi, Antonarakis et al.: "A genomic rearrangement resulting in a tandem duplication is associated with split hand-split foot malformation 3 (SHFM3) at 10q24. ..." in: Human molecular genetics, Vol. 12, Issue 16, pp. 1959-71, (2003) (PubMed).

Ilyin, Rialland, Pigeon, Guguen-Guillouzo: "cDNA cloning and expression analysis of new members of the mammalian F-box protein family." in: Genomics, Vol. 67, Issue 1, pp. 40-7, (2000) (PubMed).

Synonyme und alternative Namen zu FBXW4

F-box and WD repeat domain containing 4 (fbxw4), F-box and WD repeat domain containing 4 (FBXW4), F-box and WD repeat domain containing 4 (Fbxw4), F-box and WD-40 domain protein 4 (Fbxw4), dac, DAC, Dac, dactylin, dactylyn, FBW4, Fbw4, FBWD4, FBXW4, hag, hagoromo, SHFM3, SHSF3, wu:fk63g06

Bezeichner auf Proteinebene für FBXW4

  • F-box/WD repeat-containing protein 4
  • dactylaplasia
  • fk63g06
  • F-box and WD repeat domain containing 4
  • F-box and WD-40 domain protein 4
  • F-box and WD-40 domain-containing protein 4
  • F-box/WD repeat protein 4
  • dactylin
  • F-box protein Fbw4
  • protein hagoromo
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